Filip Krag Knop
Clinical Professor
Department of Clinical Medicine
Borgmester Ib Juuls Vej 1, 2730 Herlev
Member of:
Internal Medicine: Endocrinology
- Published
MYC mRNA expression throughout the intestine is not associated with body mass index or type 2 diabetes
Ellegaard, A. & Knop, Filip Krag, 2022, In: Endocrinology, Diabetes and Metabolism. 5, 2, 4 p., 00327.Research output: Contribution to journal › Comment/debate › Research
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A glucose-insulin-glucagon coupled model of the isoglycemic intravenous glucose infusion experiment
Subramanian, V., Bagger, J. I., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Frontiers in Physiology. 13, 20 p., 911616.Research output: Contribution to journal › Journal article › Research › peer-review
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A liver secretome gene signature-based approach for determining circulating biomarkers of NAFLD severity
Hagemann, C. A., Legart, C., Møllerhøj, M. B., Madsen, M. R., Hansen, H. H., Kønig, M. J., Helgstrand, Frederik, Hjørne, F. P., Toxværd, A., Langhoff, J. L., Kielgast, U. L., Gluud, Lise Lotte, Ægidius, H., Rigbolt, K. T. G., Vilsbøll, Tina, Jelsing, J. & Knop, Filip Krag, 2022, In: PLoS ONE. 17, 10, 19 p., e0275901.Research output: Contribution to journal › Journal article › Research › peer-review
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Acute changes in plasma glucose increases left ventricular systolic function in insulin-treated patients with type 2 diabetes and controls
Andersen, A., Jørgensen, P. G., Bagger, J., Baldassarre, M. P. A., Christensen, Mikkel Bring, Pedersen-Bjergaard, Ulrik, Lindhardt, T. B., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Diabetes, Obesity and Metabolism. 24, 6, p. 1123-1131Research output: Contribution to journal › Journal article › Research › peer-review
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Acute concomitant GIP receptor antagonism during GLP-1 receptor agonism does not affect appetite, resting energy expenditure or food intake in patients with type 2 diabetes and overweight/obesity
Stensen, S., Krogh, L. L., wbf943, wbf943, Dela, Flemming, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, Mikkel Bring, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 9, p. 1882-1887Research output: Contribution to journal › Journal article › Research › peer-review
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Azithromycin and hydroxychloroquine in hospitalised patients with confirmed COVID-19: a randomised double-blinded placebo-controlled trial
Sivapalan, P. & ProPAC-COVID writing group on behalf of the ProPAC-COVID Study Group, P. W. G. O. B. O. T. P. S. G., 2022, In: European Respiratory Journal. 59, 1, 2100752.Research output: Contribution to journal › Journal article › Research › peer-review
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Beta-Hydroxybutyrate Suppresses Hepatic Production of the Ghrelin Receptor Antagonist LEAP2
Holm, Stephanie Kjærulff, Husted, Anna Sofie, Skov, Louise Julie, Morville, T. H., Hagemann, C. A., Jorsal, T., Dall, M., Jakobsen, A., Klein, A. B., Treebak, Jonas Thue, Knop, Filip Krag, Schwartz, Thue W., Clemmensen, Christoffer & Holst, Birgitte, 2022, In: Endocrinology. 163, 6, 13 p., bqac038.Research output: Contribution to journal › Journal article › Research › peer-review
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Bile acid-farnesoid X receptor-fibroblast growth factor 19 axis in patients with short bowel syndrome: The randomized, glepaglutide phase 2 trial
Hvistendahl, M. K., Naimi, R. M., Hansen, S. H., Rehfeld, Jens Frederik, Kissow, Hannelouise, Pedersen, Jens, Dragsted, Lars Ove, Sonne, D. P., Knop, Filip Krag & Jeppesen, Palle Bekker, 2022, In: Journal of Parenteral and Enteral Nutrition. 46, 4, p. 923-935 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dasiglucagon Effectively Mitigates Postbariatric Postprandial Hypoglycemia: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial
Nielsen, C. K., Øhrstrøm, C. C., Kielgast, U. L., Hansen, D. L., Hartmann, Bolette, Holst, Jens Juul, Lund, Asger Bach, Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes Care. 45, 6, p. 1476–1481Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dyslipidæmi ved psykisk lidelse
Mohr, G. H., Barcella, C. A., Coello, K., Baandrup, Lone & Knop, Filip Krag, 2022, In: Ugeskrift for Laeger. 184, 10, 10 p., V05210439.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of short-acting exenatide added three times daily to insulin therapy on bone metabolism in type 1 diabetes
Johansen, N. J., Dejgaard, T. F., Lund, A., Schlüntz, Camilla, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Andersen, H. U. & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 2, p. 221-227Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endogenous Glucose-Dependent Insulinotropic Polypeptide Contributes to Sitagliptin-Mediated Improvement in Beta Cell Function in Patients with Type 2 Diabetes
Stensen, S., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Vilsbøll, Tina, Holst, Jens Juul, Hartmann, Bolette, Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Diabetes. 71, 10, p. 2209-2221Research output: Contribution to journal › Journal article › Research › peer-review
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Enterohepatic, gluco-metabolic, and gut microbial characterization of individuals with bile acid malabsorption
Kårhus, M. L., Sonne, David Peick, Thomasen, M., Ellegaard, A., Holst, Jens Juul, Rehfeld, Jens Frederik, Chávez-Talavera, O., Tailleux, A., Staels, B., Nielsen, Dennis Sandris, Dragsted, Lars Ove, Vilsbøll, Tina, Brønden, A. & Knop, Filip Krag, 2022, In: Gastro Hep Advances. 1, 3, p. 299-312 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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FGF21 suppresses alcohol consumption through an amygdalo-striatal circuit
Flippo, K. H., Trammell, Sam, Gillum, M. P., Aklan, I., Perez, M. B., Yavuz, Y., Smith, N. K., Jensen-Cody, S. O., Zhou, B., Claflin, K. E., Beierschmitt, A., Fink-Jensen, Anders, Knop, Filip Krag, Palmour, R. M., Grueter, B. A., Atasoy, D. & Potthoff, M. J., 2022, In: Cell Metabolism. 34, 2, p. 317-328.e6Research output: Contribution to journal › Journal article › Research › peer-review
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Fibroblast growth factor 21 is the main alcohol responsive peptide hormone in humans and individuals with alcohol use disorder exihibit increased plasma concentrations after alcohol intake
Lanng, A., Gasbjerg, Lærke Smidt, Sucksdorff, A., Svenningsen, J., Trammell, Sam, Vilsbøll, Tina, Gillum, M. & Knop, Filip Krag, 2022, In: Journal of Hepatology. 77, S1, p. S121-S121 1 p., THU006.Research output: Contribution to journal › Conference abstract in journal › Research
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GIP affects hepatic fat and brown adipose tissue thermogenesis, but not white adipose tissue transcriptome in T1D
Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergman, N. C., Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Havelund, J. F., Gorshkov, V., Kjeldsen, F., Færgeman, N. J. K., Madsen, M. R., Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 12, p. 3261–3274Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric Aspiration Improves Postprandial Glucose Tolerance Without Causing a Compensatory Increase in Appetite and Food Intake
Gether, I. M., Jensen, M. M., Nexøe-Larsen, C. C., Jorsal, T., Gasbjerg, Lærke Smidt, Naver, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Obesity Surgery. 32, p. 1385–1390Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon Clearance is Preserved in Type 2 Diabetes
Grøndahl, M. F. G., Lund, A., Bagger, J. I., Petersen, Tonny Studsgaard, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina, Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Diabetes. 71, 1, db210024.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucose-dependent insulinotropic polypeptide (GIP) induces lipolysis during stable basal insulin substitution and hyperglycemia in men with type 1 diabetes: a randomized, double-blind, placebo-controlled, crossover clinical trial
Heimburger, S. M., Nielsen, C. N., Calanna, S., Holst, Jens Juul, Vilsbøll, Tina, Knop, Filip Krag & Christensen, Mikkel Bring, 2022, In: Diabetes, Obesity and Metabolism. 24, 1, p. 142-147Research output: Contribution to journal › Journal article › Research › peer-review
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Glukagonlignende peptid 1-receptoragonister til behandling af type 2-diabetes
Andersen, A., Christensen, A. S., Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Ugeskrift for Laeger. 181, 2, V10180725.Research output: Contribution to journal › Journal article › Research › peer-review
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Hemoglobin A1c and Fructosamine Evaluated in Patients with Type 2 Diabetes Receiving Peritoneal Dialysis Using Long-Term Continuous Glucose Monitoring
Bomholt, T., Feldt-Rasmussen, Bo, Butt, Rizwan Ahmed, Borg, Rikke, Sarwary, M. H., Elung-Jensen, T., Almdal, Thomas Peter, Knop, Filip Krag, Nørgaard, Kirsten, Ranjan, A. G., Larsson, A., Rix, M. & Hornum, Mads, 2022, In: Nephron. 146, 2, p. 146-152Research output: Contribution to journal › Journal article › Research › peer-review
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Hypoglycaemia and rebound hyperglycaemia increase left ventricular systolic function in patients with type 1 diabetes
Andreasen, C. R., Andersen, A., Hagelqvist, P. G., Lauritsen, J. V., Jørgensen, P. G., Engberg, S., Faber, Jens, Hartmann, Bolette, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Diabetes, Obesity and Metabolism. 24, 10, p. 2027-2037Research output: Contribution to journal › Journal article › Research › peer-review
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Incidental finding of non-alcoholic steatohepatitis-cirrhosis
Adrian, T., Hornum, Mads, Knop, Filip Krag & Gluud, Lise Lotte, 2022, In: Endocrinology, Diabetes and Metabolism Case Reports. 2022, 1, 5 p., 22-0350.Research output: Contribution to journal › Journal article › Research › peer-review
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LEAP2 reduces postprandial glucose excursions and ad libitum food intake in healthy men
Hagemann, C. A., Jensen, M. S., Holm, Stephanie Kjærulff, Gasbjerg, Lærke Smidt, Byberg, Sarah, Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Birgitte & Knop, Filip Krag, 2022, In: Cell Reports Medicine. 3, 4, 100582.Research output: Contribution to journal › Journal article › Research › peer-review
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Liraglutide versus colesevelam for treating bile acid diarrhoea – Authors' reply
Kårhus, M. L. & Knop, Filip Krag, 2022, In: The Lancet Gastroenterology and Hepatology. 7, 12, p. 1075-1076 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Long-acting amylin analogues for the management of obesity
Mathiesen, D. S., Bagger, J. I. & Knop, Filip Krag, 2022, In: Current Opinion in Endocrinology, Diabetes and Obesity. 29, 2, p. 183-190 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mapping prohormone processing by proteases in human enteroendocrine cells using genetically engineered organoid models
Beumer, J., Bauzá-Martinez, J., Veth, T. S., Geurts, V., Boot, C., Gilliam-Vigh, H., Poulsen, Steen Seier, Knop, Filip Krag, Wu, W. & Clevers, H., 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 46, 11 p., e2212057119.Research output: Contribution to journal › Journal article › Research › peer-review
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Neurotensin secretion after Roux-en-Y gastric bypass, sleeve gastrectomy, and truncal vagotomy with pyloroplasty
Svane, M. S., Øhrstrøm, C. C., Plamboeck, A., Jørgensen, Nils Bruun, Bojsen-Møller, K. N., Dirksen, C., Martinussen, C., Vilsbøll, Tina, Hartmann, Bolette, Deacon, Carolyn F., Kristiansen, V. B., Knop, Filip Krag, Svendsen, Lars Bo, Madsbad, Sten, Holst, Jens Juul & Veedfald, Simon, 2022, In: Neurogastroenterology and Motility. 34, 1, e14210.Research output: Contribution to journal › Journal article › Research › peer-review
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Prevalence of non-alcoholic fatty liver disease in patients with chronic kidney disease: a cross-sectional study
Adrian, T., Sørensen, I. M. H., Knop, Filip Krag, Bro, S., Ballegaard, E. L. F., Nordestgaard, Børge, Fuchs, A., Kofoed, Klaus Fuglsang, Kühl, J. T., Sigvardsen, P. E., Hornum, Mads & Feldt-Rasmussen, Bo, 2022, In: Nephrology Dialysis Transplantation. 37, 10, p. 1927-1934 gfab266.Research output: Contribution to journal › Journal article › Research › peer-review
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Protocol for a 30-day randomised, parallel-group, non-inferiority, controlled trial investigating the effects of discontinuing renin-angiotensin system inhibitors in patients with and without COVID-19: The RASCOVID-19 trial
Kliim-Hansen, V., Gasbjerg, Lærke Smidt, Ellegaard, A. M., Lorentsson, H. J. N., Lynggaard, M. B., Hagemann, C. A., Legart, C., Mathiesen, D. S., Sivapalan, P., Jensen , Jens-Ulrik Stæhr , Vilsbøll, Tina, Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: BMJ Open. 12, 11, e062895.Research output: Contribution to journal › Journal article › Research › peer-review
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Safety and efficacy of liraglutide versus colesevelam for the treatment of bile acid diarrhoea: A randomised, double-blind, active-comparator, non-inferiority clinical trial
Kårhus, M. L., Brønden, A., Forman, Julie Lyng, Haaber, A., Knudsen, E., Langholz, Ebbe, Dragsted, Lars Ove, Hansen, S. H., Krakauer, M., Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2022, In: The Lancet Gastroenterology and Hepatology. 7, 10, p. 922-931 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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THERAPY OF ENDOCRINE DISEASE: Amylin and calcitonin - physiology and pharmacology
Mathiesen, D. S., Lund, A., Holst, Jens Juul, Knop, Filip Krag, Lutz, T. A. & Bagger, J. I., 2022, In: European Journal of Endocrinology. 186, 6, p. R93-R111Research output: Contribution to journal › Review › Research › peer-review
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The Accuracy of Hemoglobin A1c and Fructosamine Evaluated by Long-Term Continuous Glucose Monitoring in Patients with Type 2 Diabetes Undergoing Hemodialysis
Bomholt, T., Rix, M., Almdal, Thomas Peter, Knop, Filip Krag, Rosthøj, Susanne, Heinrich, N. S., Jørgensen, M. B., Larsson, A., Hilsted, Linda, Feldt-Rasmussen, Bo & Hornum, Mads, 2022, In: Blood Purification. 51, p. 608–616 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Glucagon Receptor Antagonist LY2409021 has No Effect on Postprandial Glucose in Type 2 Diabetes
Hædersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Forman, Julie Lyng, van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 186, 2, p. 207-221 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Liver-Alpha Cell Axis in Health and in Disease
Richter, Michael Martin, Galsgaard, Katrine Douglas, Elmelund, E., Knop, Filip Krag, Suppli, M. P., Holst, Jens Juul, Winther-Sørensen, Marie, Kjeldsen, Sasha Alexandra Sampson & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Diabetes. 71, +, p. 1852–1861Research output: Contribution to journal › Review › Research › peer-review
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The effect of curcumin on hepatic fat content in individuals with obesity
Hellmann, P. H., Bagger, J. I., Carlander, K. R., Forman, Julie Lyng, Chabanova, E., Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 11, p. 2192-2202 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The glucagon receptor antagonist LY2409021 does not affect gastrointestinal-mediated glucose disposal or the incretin effect in individuals with and without type 2 diabetes
Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Maagensen, H., Forman, Julie Lyng, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 187, 4, p. 507-518 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The impact of statins and RAS inhibitors on the association between delayed antidiabetic treatment and the risk of cardiovascular event in patients with a first HbAlc between 48-57 mmol/mol
Falkentoft, A. C., Gerds, Thomas Alexander, Knop, Filip Krag, Fosbøl, E., Køber, Lars Valeur, Torp-Pedersen, Christian, Schou, M., Bruun, Niels Eske & Ruwald, A. C., 2022, In: European Heart Journal. 43, Supplement 1, p. 2419 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Vitamin D Supplementation Improves Fasting Insulin Levels and HDL Cholesterol in Infertile Men
Holt, R., Petersen, Jørgen Holm, Dinsdale, E., Knop, Filip Krag, Juul, Anders, Jørgensen, N. & Jensen, M. B., 2022, In: Journal of Clinical Endocrinology & Metabolism. 107, 1, p. 98-108Research output: Contribution to journal › Journal article › Research › peer-review
ID: 40100368
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L-cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling
Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease
Research output: Contribution to journal › Journal article › Research › peer-review
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Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Research output: Contribution to journal › Journal article › Research › peer-review
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