Michael Givskov

Michael Givskov

Professor

Member of:


    1. 2017
    2. Discovery of novel antimycobacterial drug therapy in biofilm of pathogenic nontuberculous mycobacterial keratitis

      Aung, T. T., Chor, W. H. J., Yam, J. K. H., Givskov, Michael, Yang, L. & Beuerman, R. W., 2017, In: Ocular Surface. 15, 4, p. 770-783 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Fusaric acid and analogues as gram-negative bacterial quorum sensing inhibitors

      Thanh Tung, T., Jakobsen, Tim Holm, Dao, T. T., Fuglsang, Anja Thoe, Givskov, Michael, Christensen, Søren Brøgger & Nielsen, J., 2017, In: European Journal of Medicinal Chemistry. 126, p. 1011-1020 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      In Vitro Evaluation of Biofilm Dispersal as a Therapeutic Strategy To Restore Antimicrobial Efficacy

      Roizman, D., Vidaillac, C., Givskov, Michael & Yang, L., 2017, In: Antimicrobial Agents and Chemotherapy. 61, 10, 5 p., e01088-17.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      In vitro and In vivo efficacy of an LpxC inhibitor, CHIR-090, alone or combined with colistin against Pseudomonas aeruginosa biofilm

      Tan, J. H., Vidaillac, C., Yam, J. K. H., Chua, S. L., Givskov, Michael & Yang, L., 2017, In: Antimicrobial Agents and Chemotherapy. 61, 7, 9 p., e02223-16.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Kinase Inhibitors

      Wu, P., Givskov, Michael & Nielsen, Thomas Eiland, 2017, Drug Selectivity: An Evolving Concept in Medicinal Chemistry. Wiley-Interscience, p. 33-53 21 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    7. Published

      Metagenomic and metatranscriptomic analysis of saliva reveals disease-associated microbiota in patients with periodontitis and dental caries

      Midjord-Belstrøm, Daniel, Constancias, F., Liu, Y., Yang, L., Drautz-Moses, D. I., Schuster, S. C., Kohli, G. S., Jakobsen, Tim Holm, Holmstrup, Palle & Givskov, Michael, 2017, In: npj Biofilms and Microbiomes. 3, 8 p., 23.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Regulation of Burkholderia cenocepacia biofilm formation by RpoN and the c-di-GMP effector BerB

      Fazli, M., Rybtke, Morten Levin, Steiner, E., Weidel, E., Berthelsen, J., Groizeleau, J. D. D., Bin, W., Zhi, B. Z., Yaming, Z., Kaever, V., Givskov, Michael, Hartmann, R. W., Eberl, L. & Tolker-Nielsen, Tim, 2017, In: MicrobiologyOpen. 6, 4, 13 p., e00480.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Synergy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Inhibiting P.aeruginosa Quorum Sensing

      Fong, J., Zhang, C., Yang, R., Boo, Z. Z., Tan, S. K., Nielsen, Thomas Eiland, Givskov, Michael, Wu, B., Su, H. & Yang, L., 2017, bioRxiv, 27 p.

      Research output: Working paperPreprint

    10. Published

      The Acquisition of Resistance to Carbapenem and Macrolide-mediated Quorum Sensing Inhibition by Pseudomonas aeruginosa via a Novel Integrative and Conjugative Element ICETn43716385

      Ding, Y., Teo, J., Drautz-Moses, D. I., Schuster, S. C., Givskov, Michael & Yang, L., 2017, bioRxiv, 95 p.

      Research output: Working paperPreprint

    11. Published

      Gauging and visualizing c-di-GMP levels in pseudomonas aeruginosa using fluorescence-based biosensors

      Rybtke, Morten Levin, Chua, S. L., Yam, J. K. H., Givskov, Michael, Yang, L. & Tolker-Nielsen, Tim, Jan 2017, c-di-GMP Signaling: Methods and Protocols. Sauer, K. (ed.). Humana Press, Vol. 1657. p. 87-98 12 p. (Methods in Molecular Biology, Vol. 1657).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    12. Published

      High-throughput screening for compounds that modulate the cellular c-di-GMP level in bacteria

      Groizeleau, J., Andersen, Jens Bo, Givskov, Michael, Berthelsen, J. & Tolker-Nielsen, Tim, Jan 2017, c-di-GMP Signaling: Methods and Protocols. Sauer, K. (ed.). Humana Press, Vol. 1657. p. 455-470 16 p. (Methods in Molecular Biology, Vol. 1657).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    13. Published

      Disulfide Bond-Containing Ajoene Analogues As Novel Quorum Sensing Inhibitors of Pseudomonas aeruginosa

      Fong, J., Yuan, M., Jakobsen, Tim Holm, Mortensen, K. T., Delos Santos, M. M. S., Chua, S. L., Yang, L., Tan, C. H., Nielsen, Thomas Eiland & Givskov, Michael, 12 Jan 2017, In: Journal of Medicinal Chemistry. 60, 1, p. 215-227

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Cholesterol crystals enhance TLR2-and TLR4-mediated pro-inflammatory cytokine responses of monocytes to the proatherogenic oral bacterium Porphyromonas gingivalis

      Køllgaard, T. M. S., Enevold, Christian, Bendtzen, K., Hansen, Peter Riis, Givskov, Michael, Holmstrup, Palle & Nielsen, Claus Henrik, 24 Feb 2017, In: P L o S One. 12, 2, 14 p., 0172773.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Bacterial Biofilm Control by Perturbation of Bacterial Signaling Processes

      Jakobsen, Tim Holm, Tolker-Nielsen, Tim & Givskov, Michael, Sep 2017, In: International Journal of Molecular Sciences. 18, 9, 27 p., 1970.

      Research output: Contribution to journalReviewResearchpeer-review

    16. Published

      A Linker for the Solid-Phase Synthesis of Hydroxamic Acids and Identification of HDAC6 Inhibitors

      Bang, C. G., Jensen, J. F., O'Hanlon Cohrt, E., Olsen, L. B., Siyum, S. G., Mortensen, K. T., Skovgaard, T., Berthelsen, J., Yang, L., Givskov, Michael, Qvortrup, K. & Nielsen, Thomas Eiland, Oct 2017, In: ACS Combinatorial Science. 19, 10, p. 657-669 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Reduced intracellular c-di-GMP content increases expression of quorum sensing-regulated genes in Pseudomonas aeruginosa

      Chua, S. L., Liu, Y., Li, Y., Ting, H. J., Kohli, G. S., Cai, Z., Suwanchaikasem, P., Goh, K. K. K., Ng, S. P., Tolker-Nielsen, Tim, Yang, L. & Givskov, Michael, Oct 2017, In: Frontiers in Cellular and Infection Microbiology. 7, 8 p., 451.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. 2018
    19. Published

      Acquisition of resistance to carbapenem and macrolide-mediated quorum sensing inhibition by Pseudomonas aeruginosa via ICETn4371 6385

      Ding, Y., Teo, J. W. P., Drautz-Moses, D. I., Schuster, S. C., Givskov, Michael & Yang, L., 2018, In: Communications Biology. 1, 10 p., 57.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      CDy14: A novel biofilm probe targeting exopolysaccharide Psl

      Kwon, H. Y., Kim, J. Y., Lee, J. Y., Yam, J. K. H., Hultqvist, Louise Dahl, Xu, W., Rybtke, Morten Levin, Tolker-Nielsen, Tim, Kim, J. J., Kang, N. Y., Yang, L., Park, S. J., Givskov, Michael & Chang, Y. T., 2018, In: Chemical Communications. 54, 84, p. 11865-11868 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Characterization of a novel multidrug resistance plasmid pSGB23 isolated from Salmonella enterica subspecies enterica serovar Saintpaul

      Ding, Y., Zwe, Y. H., Chin, S. F., Kohli, G. S., Drautz-Moses, D. I., Givskov, Michael, Schlundt, J., Schuster, S. C., Yuk, H. G. & Yang, L., 2018, In: Gut Pathogens. 10, 5 p., 20.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Imaging N-acyl homoserine lactone quorum sensing in vivo

      Hultqvist, Louise Dahl, Alhede, M., Jakobsen, Tim Holm, Givskov, Michael & Bjarnsholt, Thomas, 2018, Quorum Sensing: Methods and Protocols. Leoni, L. & Rampion, G. (eds.). Humana Press, Vol. 1673. p. 203-212 10 p. (Methods in Molecular Biology; No. 1673).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    23. Published

      Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin

      Woetmann, Anders , Alhede, M., Dabelsteen, Sally, Bjarnsholt, Thomas, Rybtke, Morten Levin, Nastasi, C., Krejsgaard, T., Andersen, Mads Hald, Bonefeld, Charlotte Menne, Geisler, Carsten, Givskov, Michael & Ødum, Niels, 2018, In: OncoTarget. 9, 28, p. 19481-19489 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Matrix Polysaccharides and SiaD Diguanylate Cyclase Alter Community Structure and Competitiveness of Pseudomonas aeruginosa during Dual-Species Biofilm Development with Staphylococcus aureus

      Chew, S. C., Yam, J. K. H., Matysik, A., Seng, Z. J., Klebensberger, J., Givskov, Michael, Doyle, P., Rice, S. A., Yang, L. & Kjelleberg, S., 2018, In: mBio. 9, 6, 16 p., e00585-18.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Qualitative and Quantitative Determination of Quorum Sensing Inhibition In Vitro

      Jakobsen, Tim Holm, Alhede, M., Hultqvist, Louise Dahl, Bjarnsholt, Thomas & Givskov, Michael, 2018, Quorum Sensing: Methods and Protocols. Springer, Vol. 1673. p. 275-285 11 p. (Methods in molecular biology (Clifton, N.J.)).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    26. Published

      Repurposing the anticancer drug cisplatin with the aim of developing novel Pseudomonas aeruginosa infection control agents

      Yuan, M., Chua, S. L., Liu, Y., Drautz-Moses, D. I., Hoong Yam, J. K., Aung, T. T., Beuerman, R. W., Santillan Salido, M. M., Schuster, S. C., Tan, C. H., Givskov, Michael, Yang, L. & Nielsen, Thomas Eiland, 2018, In: Beilstein Journal of Organic Chemistry. 14, p. 3059-3069 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      The Bacterial Toxin CNF1 Induces Activation and Maturation of Human Monocyte-Derived Dendritic Cells

      Gall Mas, Laura, Fabbri, A., Namini, Martin Rich Javadi, Givskov, Michael, Fiorentini, C. & Krejsgaard, T., 2018, In: International Journal of Molecular Sciences . 19, 5, 11 p., 1408.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 5838523