René Villadsen
Associate Professor
Morphogenesis and Differentiation Program
Blegdamsvej 3
2200 København N.
- 2000
- Published
Complete loss of wild-type TP53 in a nontransformed human epithelial cell line is preceded by a phase during which a heterozygous TP53 mutant effectively outgrows the homozygous wild-type cells
Villadsen, René, Nielsen, K. V., Bolund, L. & Briand, P., 1 Jan 2000, In: Cancer Genetics and Cytogenetics. 116, 1, p. 28-34 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
The plasticity of human breast carcinoma cells is more than epithelial to mesenchymal conversion
Petersen, Ole William, Nielsen, H. L., Gudjonsson, T., Villadsen, René, Rønnov-Jessen, Lone & Bissell, M. J., 2001, In: Breast Cancer Research (Online Edition). 3, p. 213-217Research output: Contribution to journal › Review › Research
- 2002
- Published
Differential expression of a chloride intracellular channel gene, CLIC4, in transforming growth factor-β1-mediated conversion of fibroblasts to myofibroblasts
Rønnov-Jessen, Lone, Villadsen, René, Edwards, J. C. & Petersen, Ole William, 2002, In: American Journal of Pathology. 161, 2, p. 471-480 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of EPSTI1, a novel gene induced by epithelial-stromal interaction in human breast cancer
Nielsen, H. L., Rønnov-Jessen, Lone, Villadsen, René & Petersen, Ole William, 2002, In: Genomics. 79, 5, p. 703-10 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties
Gudjonsson, T., Villadsen, René, Nielsen, H. L., Rønnov-Jessen, Lone, Bissell, M. J. & Petersen, Ole William, 2002, In: Genes Dev. vol. 16(6), p. 693-706Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition
Gudjonsson, T., Rønnov-Jessen, Lone, Villadsen, René, Rank, F. E., Bissell, M. J. & Petersen, Ole William, 2002, In: Journal of Cell Science. 115, p. 39-50Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Epithelial progenitor cell lines as models of normal breast morphogenesis and neoplasia
Petersen, Ole William, Gudjonsson, T., Villadsen, René, Bissell, M. J. & Rønnov-Jessen, Lone, 2003, In: Cell Proliferation. 36 Suppl 1, p. 33-44 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epithelial to Mesenchymal Transition in Human Breast Cancer Can Provide a Nonmalignant Stroma
Petersen, Ole William, Nielsen, H. L., Gudjonsson, T., Villadsen, René, Rank, F. E., Niebuhr, E., Bisell, M. J. & Rønnov-Jessen, Lone, 2003, In: American Journal og Pathology. Vol. 162, p. 391-402Research output: Contribution to journal › Journal article › Research › peer-review
- Published
To create the correct microenvironment: Three-dimensional heterotypic collagen assays for human breast epithelial morphogenesis and neoplasia
Gudjonsson, T., Rønnov-Jessen, Lone, Villadsen, René, Bissell, M. J. & Petersen, Ole William, 2003, In: Methods. Vol. 30, p. 247-255Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Collagen gel contraction serves to rapidly distinguish epithelial- and mesenchymal-derived cells irrespective of alpha-smooth muscle actin expression
Nielsen, H. L., Gudjonsson, T., Villadsen, René, Rønnov-Jessen, Lone & Petersen, Ole William, 2004, In: In Vitro Cellular & Developmental Biology - Animal. 39, 7, p. 297-303 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immortalization protocols used in cell culture models of human breast morphogenesis
Gudjonsson, T., Villadsen, René, Rønnov-Jessen, Lone & Petersen, O. W., 2004, In: Cellular and molecular life sciences : CMLS. 61, 19-20, p. 2523-34 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Annexin A8 Is Up-Regulated During Mouse Mammary Gland Involution and Predicts Poor Survival in Breast Cancer
Stein, T., Price, K. N., Morris, J. S., Heath, V. J., Ferrier, R. K., Bell, A. K., Pringle, M., Villadsen, René, Petersen, Ole William, Sauter, G., Bryson, G., Mallon, E. A. & Gusterson, B. A., 2005, In: Clinical Cancer Research. 11, p. 6872-6879Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maintenance of Cell Type Diversification in the Human Breast
Rubner Fridriksdottir, A. J., Villadsen, René, Gudjonsson, T. & Petersen, Ole William, 2005, In: Journal of Mammary Gland Biology and Neoplasia. 10, 1, p. 61-74Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In search of a stem cell hierarchy in the human breast and its relevance to breast cancer evolution
Villadsen, René, Nov 2005, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 113, 11-12, p. 903-21 19 p.Research output: Contribution to journal › Review › Research › peer-review
- 2007
- Published
Evidence for a stem cell hierarchy in the adult human breast
Villadsen, René, Fridriksdottir, A. J., Rønnov-Jessen, Lone, Gudjonsson, T., Rank, F., LaBarge, M. A., Bissell, M. J. & Petersen, Ole William, 2007, In: Journal of Cell Biology. 177, 1, p. 87-101 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Dissection of a stem cell hierarchy in the human breast
Rubner Fridriksdottir, A. J., Villadsen, René, Kim, Jiyoung, Rønnov-Jessen, Lone & Petersen, Ole William, 2008, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. p. 412 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- 2009
- Published
Human mammary progenitor cell fate decisions are productsof interactions with combinatorial microenvironments
LaBarge, M. A., Nelson, C. M., Villadsen, René, Rubner Fridriksdottir, A. J., Ruth, J. R., Stampfer, M. R., Petersen, Ole William & Bissell, M. J., 2009, In: Integrative Biology. 1, p. 70-79 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Epithelial-stromal interaction 1 (EPSTI1) substitutes for peritumoral fibroblasts in the tumor microenvironment
De Neergaard, M., Kim, Jiyoung, Villadsen, René, Fridriksdóttir, A. J. R., Rank, F., Timmermans-Wielenga, V., Langerød, A., Børresen-Dale, A., Petersen, Ole William & Rønnov-Jessen, Lone, 2010, In: American Journal of Pathology. 176, 3, p. 1229-1240 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Endothelial induced EMT in breast epithelial cells with stem cell properties
Sigurdsson, V., Hilmarsdottir, B., Sigmundsdottir, H., Fridriksdottir, A. J. R., Ringnér, M., Villadsen, René, Borg, A., Agnarsson, B. A., Petersen, Ole William, Magnusson, M. K. & Gudjonsson, T., 2011, In: P L o S One. 6, 9, p. e23833Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells
Vaapil, M., Helczynska, K., Villadsen, René, Petersen, Ole William, Johansson, E., Beckman, S., Larsson, C., Påhlman, S. & Jögi, A., 2012, In: P L o S One. 7, 9, p. e46543Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity
Kim, Jiyoung, Villadsen, René, Sørlie, T., Fogh, L., Grønlund, S. Z., Fridriksdóttir, A. J. R., Kuhn, I., Rank, F., Wielenga, V. T., Solvang, H., Edwards, P. A. W., Børresen-Dale, A., Rønnov-Jessen, Lone, Bissell, M. J. & Petersen, Ole William, 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 16, p. 6124-6129 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia
Garbe, J. C., Pepin, F., Pelissier, F. A., Sputova, K., Fridriksdottir, A. J., Guo, D. E., Villadsen, René, Park, M., Petersen, Ole William, Borowsky, A. D., Stampfer, M. R. & Labarge, M. A., Jul 2012, In: Cancer Research. 72, 14, p. 3687-701 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
A Marker of Endocrine Receptor-Positive Cells, CEACAM6, Is Shared by Two Major Classes of Breast Cancer: Luminal and HER2-Enriched
Balk-Møller, E., Kim, Jiyoung, Hopkinson, B., Timmermans-Wielenga, V., Petersen, Ole William & Villadsen, René, Apr 2014, In: American Journal of Pathology. 184, 4, p. 1198-1208 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture
Fridriksdóttir, A. J. R., Kim, Jiyoung, Villadsen, René, Klitgaard, M. C., Hopkinson, B. M., Petersen, Ole William & Rønnov-Jessen, Lone, 2015, In: Nature Communications. 6, 12 p., 8786.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Evidence of two distinct functionally specialized fibroblast lineages in breast stroma
Morsing, M., Klitgaard, M. C., Jafari Kermani, Abbas, Villadsen, René, Kassem, Moustapha Saad El-Deen, Petersen, Ole William & Rønnov-Jessen, Lone, 2016, In: Breast Cancer Research (Online). 18, 11 p., 108.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4354
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Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
242
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Evidence of two distinct functionally specialized fibroblast lineages in breast stroma
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
218
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Warburg Effect Metabolism Drives Neoplasia in a Drosophila Genetic Model of Epithelial Cancer
Research output: Contribution to journal › Journal article › Research › peer-review
Published