Thomas Mandel Clausen

Thomas Mandel Clausen

Guest Researcher

Member of:

  • VAR2CSA team

ORCID: 0000-0001-7543-9622

Publication year:
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  1. Published

    The specificity of the malarial VAR2CSA protein for chondroitin sulfate depends on 4-O-sulfation and ligand accessibility

    Spliid, C. B., Toledo, A. G., Sanderson, P., Mao, Y., Gatto, F., Gustavsson, Tobias, Choudhary, Swati, Saldanha, A. L., Vogelsang, R. P., Gögenur, Ismail, Theander, Thor Grundtvig, Leach, F. E., Amster, I. J., Esko, J. D., Salanti, Ali & Clausen, Thomas Mandel, 2021, In: The Journal of Biological Chemistry. 297, 6, 15 p., 101391.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Beware, commercial chondroitinases vary in activity and substrate specificity

    Spliid, C. B., Toledo, A. G., Salanti, Ali, Esko, J. D. & Clausen, Thomas Mandel, 2021, In: Glycobiology. 31, 2, p. 103-115 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Molecular dissection of placental malaria protein VAR2CSA interaction with a chemo-enzymatically synthesized chondroitin sulfate library

    Sugiura, N., Clausen, Thomas Mandel, Shioiri, T., Gustavsson, Tobias, Watanabe, H. & Salanti, Ali, Dec 2016, In: Glycoconjugate Journal. 33, 6, p. 985-994 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Identification of global inhibitors of cellular glycosylation

    Sørensen, D. M., Büll, C., Madsen, T. D., Lira-Navarrete, E., Clausen, T. M., Clark, A. E., Garretson, A. F., Karlsson, R., Pijnenborg, J. F. A., Yin, X., Miller, R. L., Chanda, S. K., Boltje, T. J., Schjoldager, K. T., Vakhrushev, S. Y., Halim, A., Esko, J. D., Carlin, A. F., Hurtado-Guerrero, R., Weigert, R. & 2 others, Clausen, Henrik & Narimatsu, Yoshiki, 2023, In: Nature Communications. 14, 1, 19 p., 948.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    An affinity chromatography and glycoproteomics workflow to profile the chondroitin sulfate proteoglycans that interact with malarial VAR2CSA in the placenta and in cancer

    Toledo, A. G., Pihl, J., Spliid, C. B., Persson, A., Nilsson, J., Pereira, M. A., Gustavsson, Tobias, Choudhary, Swati, Zarni Oo, H., Black, P. C., Daugaard, M., Esko, J. D., Larson, G., Salanti, Ali & Clausen, Thomas Mandel, 2020, In: Glycobiology. 30, 12, p. 989-1002 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding

    Wang, Kaituo, Dagil, Robert, Lavstsen, Thomas, Misra, S. K., Spliid, C. B., Wang, Y., Gustavsson, Tobias, Sandoval, D. R., Vidal-Calvo, E. E., Choudhary, Swati, Agerbæk, Mette Ørskov, Lindorff-Larsen, Kresten, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sharp, J. S., Clausen, Thomas Mandel, Gourdon, Pontus Emanuel & Salanti, Ali, 2021, In: Nature Communications. 12, 1, 10 p., 2956.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate

    Weiss, R. J., Spahn, P. N., Chiang, A. W. T., Liu, Q., Li, J., Hamill, K. M., Rother, S., Clausen, Thomas Mandel, Hoeksema, M. A., Timm, B. M., Godula, K., Glass, C. K., Tor, Y., Gordts, P. L. S. M., Lewis, N. E. & Esko, J. D., 2021, In: Nature Chemical Biology. 17, p. 684–692

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Clofazimine broadly inhibits coronaviruses including SARS-CoV-2

    Yuan, S., Yin, X., Meng, X., Chan, J. F. W., Ye, Z. W., Riva, L., Pache, L., Chan, C. C. Y., Lai, P. M., Chan, C. C. S., Poon, V. K. M., Lee, A. C. Y., Matsunaga, N., Pu, Y., Yuen, C. K., Cao, J., Liang, R., Tang, K., Sheng, L., Du, Y. & 25 others, Xu, W., Lau, C. Y., Sit, K. Y., Au, W. K., Wang, R., Zhang, Y. Y., Tang, Y. D., Clausen, Thomas Mandel, Pihl, J., Oh, J., Sze, K. H., Zhang, A. J., Chu, H., Kok, K. H., Wang, D., Cai, X. H., Esko, J. D., Hung, I. F. N., Li, R. A., Chen, H., Sun, H., Jin, D. Y., Sun, R., Chanda, S. K. & Yuen, K. Y., 2021, In: Nature. 593, p. 418–423

    Research output: Contribution to journal › Journal article › Research › peer-review

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