Bo Torben Porse

Bo Torben Porse

Professor, Clinical Professor

Member of:

  • Internal Medicine: Haematology

ORCID: 0000-0001-6043-0844

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  1. Published

    Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates

    Gu, X., Ebrahem, Q., Mahfouz, R. Z., Hasipek, M., Enane, F., Radivoyevitch, T., Rapin, N., Przychodzen, B., Hu, Z., Balusu, R., Cotta, C. V., Wald, D., Argueta, C., Landesman, Y., Martelli, M. P., Falini, B., Carraway, H., Porse, B. T., Maciejewski, J., Jha, B. K. & 1 others, Saunthararajah, Y., 2018, In: The Journal of Clinical Investigation. 128, 10, p. 4260-4279 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    BloodSpot 3.0: a database of gene and protein expression data in normal and malignant haematopoiesis

    Gíslason, M. H., Demircan, G. S., Prachar, Marek, Furtwängler, Benjamin, Schwaller, J., Schoof, E., Porse, Bo Torben, Rapin, N. & Bagger, F., 2024, In: Nucleic acids symposium series. 52, D1, p. D1138–D1142 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway

    Hansen, A. M., Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Jakobsen, J. S., Kalvisa, A., Tapia, Marta Cecylia, Gordon, Sandra, Ambri, F., Bagger, F. O., Pandey, D., Helin, K. & Porse, Bo Torben, 2022, In: Science Advances. 8, 11, eabf8627.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Phosphorylation of Serine 248 of C/EBPa Is Dispensable for Myelopoiesis but Its Disruption Leads to a Low Penetrant Myeloid Disorder with Long Latency

    Hasemann, M. S., Schuster, Mikkel Bruhn, Frank, Anne-Katrine, Theilgaard-Mønch, Kim, Pedersen, T. Å., Nerlov, C. & Porse, Bo Torben, 2012, In: P L o S One. 7, 6, p. e38841

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    C/EBPα Is Required for Long-Term Self-Renewal and Lineage Priming of Hematopoietic Stem Cells and for the Maintenance of Epigenetic Configurations in Multipotent Progenitors

    Hasemann, M. S., Lauridsen, F. K. B., Waage, J., Jakobsen, J. S., Frank, Anne-Katrine, Schuster, Mikkel Bruhn, Rapin, N. P. J., Bagger, F. O., Hoppe, P. S., Schroeder, T. & Porse, Bo Torben, Jan 2014, In: P L o S Genetics (Online). 10, 1, p. 1-10 10 p., e1004079.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Mutation of C/EBPalpha predisposes to the development of myeloid leukemia in a retroviral insertional mutagenesis screen.

    Hasemann, M. S., Damgaard, I., Schuster, Mikkel Bruhn, Theilgaard-Mønch, Kim, Sørensen, A. B., Mrsic, A., Krugers, T., Ylstra, B., Pedersen, F. S., Nerlov, C. & Porse, Bo Torben, 2008, In: Blood. 111, 8, p. 4309-21 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression

    Heyes, E., Wilhelmson, Anna, Wenzel, Anne, Manhart, G., Eder, T., Schuster, Mikkel Bruhn, Rzepa, E., Pundhir, Sachin, D’Altri, T., Frank, Anne-Katrine, Gentil, C., Woessmann, J., Schoof, E. M., Meggendorfer, M., Schwaller, J., Haferlach, T., Grebien, F. & Porse, Bo Torben, 2023, In: Nature Communications. 14, 18 p., 6185.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The eha research roadmap: normal hematopoiesis

    Jaffredo, T., Balduini, A., Bigas, A., Bernardi, R., Bonnet, D., Canque, B., Charbord, P., Cumano, A., Delwel, R., Durand, C., Fibbe, W., Forrester, L., De Franceschi, L., Ghevaert, C., Gjertsen, B., Gottgens, B., Graf, T., Heidenreich, O., Hermine, O., Higgs, D. & 21 others, Kleanthous, M., Klump, H., Kouskoff, V., Krause, D., Lacaud, G., Lo Celso, C., Martens, J. H. A., Méndez-Ferrer, S., Menendez, P., Oostendorp, R., Philipsen, S., Porse, Bo Torben, Raaijmakers, M., Robin, C., Stunnenberg, H., Theilgaard-Mønch, Kim, Touw, I., Vainchenker, W., Corrons, J. L. V., Yvernogeau, L. & Schuringa, J. J., 2021, In: HemaSphere. 5, 12, e669.

    Research output: Contribution to journal › Review › Research › peer-review

  9. Published

    Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML

    Jakobsen, J. S., Laursen, L. G., Schuster, Mikkel Bruhn, Pundhir, Sachin, Schoof, E., Ge, Y., d'Altri, T., Vitting-Seerup, K., Rapin, N., Gentil, C., Jendholm, J., Theilgaard-Mønch, Kim, Reckzeh, K., Bullinger, L., Döhner, K., Hokland, P., Fitzgibbon, J. & Porse, Bo Torben, 2019, In: Science Advances. 5, 7, p. 1-16 16 p., eaaw4304.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Amplification of pico-scale DNA mediated by bacterial carrier DNA for small-cell-number transcription factor ChIP-seq

    Jakobsen, J. S., Bagger, F. O., Hasemann, M. S., Schuster, Mikkel Bruhn, Frank, Anne-Katrine, Waage, J., Vitting-Seerup, K. & Porse, Bo Torben, 2015, In: BMC Genomics. 16, p. 46

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Temporal mapping of CEBPA and CEBPB binding during liver regeneration reveals dynamic occupancy and specific regulatory codes for homeostatic and cell cycle gene batteries

    Jakobsen, J. S., Waage, J., Rapin, N., Bisgaard, Hanne Cathrine, Larsen, F. S. & Porse, Bo Torben, Apr 2013, In: Genome Research. 23, 4, p. 592-603 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Immunophenotypical characterization of human neutrophil differentiation

    Jensen, H. M., Jendholm, J., Fossum, A., Porse, Bo Torben, Borregaad, N. & Theilgaard-Mønch, Kim, 7 Jun 2011, In: Journal of Leukocyte Biology. p. 629-634 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Inhibition of Upf2-Dependent Nonsense-Mediated Decay Leads to Behavioral and Neurophysiological Abnormalities by Activating the Immune Response

    Johnson, J. L., Stoica, L., Liu, Y., Zhu, P. J., Bhattacharya, A., Buffington, S., Huq, R., Eissa, N. T., Larsson, O., Porse, B. T., Domingo, D., Nawaz, U., Carroll, R., Jolly, L., Scerri, T. S., Kim, H-G., Brignell, A., Coleman, M. J., Braden, R., Kini, U. & 11 others, Jackson, V., Baxter, A., Bahlo, M., Scheffer, I. E., Amor, D. J., Hildebrand, M. S., Bonnen, P. E., Beeton, C., Gecz, J., Morgan, A. T. & Costa-Mattioli, M., 2019, In: Neuron. 104, 4, p. 665-679 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    LEP promoter methylation in the initiation and progression of clonal cytopenia of undetermined significance and myelodysplastic syndrome

    Kaastrup, K., Gillberg, Linn, Mikkelsen, Stine Ulrik, mxz703, mxz703, Schöllkopf, C., Mortensen, B. K., Porse, Bo Torben, Hansen, Jakob Werner & Grønbæk, Kirsten, 2023, In: Clinical Epigenetics. 15, 13 p., 91.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    ERG Functionally Overlaps with Other Ets Proteins in Promoting TH9 Cell Expression of IL9 during Allergic Lung Inflammation

    Kharwadkar, R., Ulrich, B. J., Chu, M., Koh, B., Hufford, M. M., Fu, Y., Birdsey, G. M., Porse, Bo Torben, Randi, A. M. & Kaplan, M. H., 2023, In: Journal of Immunology. 210, 5, p. 537-546

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Peptidyl transferase antibiotics perturb the relative positioning of the 3'-terminal adenosine of P/P'-site-bound tRNA and 23S rRNA in the ribosome

    Kirillov, S. V., Porse, Bo Torben & Garrett, R. A., 1999, In: RNA: A publication of the RNA Society. 5, 8, p. 1003-13 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Movement of the 3'-end of tRNA through the peptidyl transferase centre and its inhibition by antibiotics

    Kirillov, S., Porse, Bo Torben, Vester, B., Woolley, P. & Garrett, Roger Antony, 1997, In: FEBS Letters. 406, 3, p. 223-233 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.

    Kirstetter, P., Anderson, K., Porse, Bo Torben, Jacobsen, S. E. W. & Nerlov, C., 2006, In: Nature Immunology. 7, 10, p. 1048-56 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells.

    Kirstetter, P., Schuster, Mikkel Bruhn, Bereshchenko, O., Moore, S., Dvinge, H., Kurz, E., Theilgaard-Mønch, Kim, Månsson, R., Pedersen, T. A., Pabst, T., Schrock, E., Porse, Bo Torben, Jacobsen, S. E. W., Bertone, P., Tenen, D. G. & Nerlov, C., 2008, In: Cancer Cell. 13, 4, p. 299-310 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Integrative analysis of histone ChIP-seq and transcription data using Bayesian mixture models

    Klein, H., Schäfer, M., Porse, Bo Torben, Hasemann, M. S., Ickstadt, K. & Dugas, M., 22 Jan 2014, In: Bioinformatics.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation

    Knudsen, K. J., Rehn, M. C., Hasemann, M. S., Rapin, N. P. J., Bagger, F. O., Ohlsson, E. K., Willer, A., Frank, Anne-Katrine, Søndergaard, E., Jendholm, L. J., Thorén, L. A. M., Lee, J., Rak, J., Theilgaard-Mønch, Kim & Porse, Bo Torben, 2015, In: Genes & Development. 29, p. 1915-1929 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Differences in Cell Cycle Status Underlie Transcriptional Heterogeneity in the HSC Compartment

    Lauridsen, F. K., Jensen, T. L., Rapin, N., Aslan, D., Wilhelmson, Anna, Pundhir, Sachin, Rehn, M., Paul, F., Giladi, A., Hasemann, M. S., Serup, Palle, Amit, I. & Porse, Bo Torben, 2018, In: Cell Reports. 24, 3, p. 766-780 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    microRNA-9 targets the long non-coding RNA MALAT1 for degradation in the nucleus

    Leucci, E., Patella, F., Waage, J., Holmstrøm, K., Lindow, M., Porse, Bo Torben, Kauppinen, S. & Lund, Anders H., 29 Aug 2013, In: Scientific Reports. 3, p. 2535

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    A conserved chloramphenicol binding site at the entrance to the ribosomal peptide exit tunnel.

    Long, K. S. & Porse, Bo Torben, 2003, In: Nucleic Acids Research. 31, 24, p. 7208-15 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    A sparsomycin-resistant mutant of Halobacterium salinarium lacks a modification at nucleotide U2603 in the peptidyl transferase centre of 23 S rRNA

    Lázaro, E., Rodriguez-Fonseca, C., Porse, Bo Torben, Ureña, D., Garrett, Roger Antony & Ballesta, J. P. G., 16 Aug 1996, In: Journal of Molecular Biology. 261, 2, p. 231-238 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 4985646