Nikos Hatzakis
Professor
Department of Chemistry
Universitetsparken 5
2100 København Ø
- 2001
Oxidation of benzyl alcohols by dimethyldioxirane. The question of concerted versus stepwise mechanisms probed by kinetic isotope effects
Angelis, Y. S., Hatzakis, Nikos, Smonou, I. & Orfanopoulos, M., 2001, In: Tetrahedron Letters. 42, 22, p. 3753-3756 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
Ferulic acid esterase from Humicola Insolens catalyzes enantioselective transesterification of secondary alcohols
Hatzakis, Nikos, Daphnomili, D. & Smonou, I., 2003, In: Journal of Molecular Catalysis B: Enzymatic. 21, 4-6, p. 309-311 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
Enantioselectivity and diastereoselectivity in the transesterification of secondary alcohols mediated by feruloyl esterase from Humicola insolens
Hatzakis, Nikos & Smonou, I., 2004, In: Tetrahedron Letters. 45, 13, p. 2755-2757 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
Functional nano-sized assemblies from amphiphilic biohybrid macromolecules
Cornelissen, J., Dirks, A., Reynhout, I., Opsteen, J., Hatzakis, Nikos, Sly, J., Rowan, A., van Hest, J. & Nolte, R., 2005, In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.Research output: Contribution to journal › Conference abstract in journal › Research
Preparation of biohybrid amphiphiles via the copper catalysed Huisgen [3 + 2] dipolar cycloaddition reaction
Dirks, A. J., Van Berkel, S. S., Hatzakis, Nikos, Opsteen, J. A., Van Delft, F. L., Cornelissen, J. J. L. M., Rowan, A. E., Van Hest, J. C. M., Rutjes, F. P. J. T. & Nolte, R. J. M., 7 Sep 2005, In: Chemical Communications. 33, p. 4172-4174 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
Asymmetric transesterification of secondary alcohols catalyzed by feruloyl esterase from Humicola insolens
Hatzakis, Nikos & Smonou, I., 2005, In: Bioorganic Chemistry. 33, 4, p. 325-337 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
Bionanoconjugation via click chemistry: The creation of functional hybrids of lipases and gold nanoparticles
Brennan, J. L., Hatzakis, Nikos, Tshikhudo, T. R., Dirvianskyte, N., Razumas, V., Patkar, S., Vind, J., Svendsen, A., Nolte, R. J. M., Rowan, A. E. & Brust, M., 2006, In: Bioconjugate Chemistry. 17, 6, p. 1373-1375 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional biohybrid amphiphiles
Dirks, A. J., Hatzakis, Nikos, Cornelissen, J. J. L. M. & Nolte, R. J. M., 2006, In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.Research output: Contribution to journal › Conference abstract in journal › Research
Do enzymes sleep and work?
Engelkamp, H., Hatzakis, Nikos, Hofkens, J., De Schryver, F. C., Nolte, R. J. M. & Rowan, A. E., 2006, In: Chemical Communications. 9, p. 935-940 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
From single to multienzyme assemblies: Do enzymes sleep and work?
Hatzakis, Nikos, Engelkamp, H., Nolte, R. & Rowan, A., 2006, In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.Research output: Contribution to journal › Journal article › Research
Synthesis and single enzyme activity of a clicked lipase-BSA hetero-dimer
Hatzakis, Nikos, Engelkamp, H., Velonia, K., Hofkens, J., Christianen, P. C. M., Svendsen, A., Patkar, S. A., Vind, J., Maan, J. C., Rowan, A. E. & Nolte, R. J. M., 2006, In: Chemical Communications. 19, p. 2012-2014 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
POLY 391-Assembly strategies for enzyme immobilization
Lambermon, M., Hendriks, L. J., Schoffelen, S., Vos, M., Hatzakis, Nikos, Carette, N., Rowan, A. E., Cornelissen, J., Michon, T., Sommerdijk, N. A. J. M. & van Hest, J. C. M., 2006, In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.Research output: Contribution to journal › Conference abstract in journal › Research
POLY 553-Biohybrid block copolymer architectures by "click" chemistry
Opsteen, J. A., Dirks, A. J., van Berkel, S. S., Hatzakis, Nikos, Brinkhuis, R. P., Reijnders, M. E. G. & van Hest, J. C. M., 2006, In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.Research output: Contribution to journal › Conference abstract in journal › Research
- 2007
Positional assembly of enzymes in polymersome nanoreactors for cascade reactions
Vriezema, D. M., Garcia, P. M. L., Oltra, N. S., Hatzakis, Nikos, Kuiper, S. M., Nolte, R. J. M., Rowan, A. E. & van Hest, J. C. M., 2007, In: Angewandte Chemie International Edition. 46, 39, p. 7378-7382 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- 2008
- Published
β-Cyclodextrin-appended giant amphiphile: Aggregation to vesicle polymersomes and immobilisation of enzymes
Felici, M., Marzá-Pérez, M., Hatzakis, Nikos, Nolte, R. J. M. & Feiters, M. C., 2008, In: Chemistry - A European Journal. 14, 32, p. 9914-9920 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The enzyme mechanism of nitrite reductase studied at single-molecule level
Kuznetsova, S., Zauner, G., Aartsma, T., Engelkamp, H., Hatzakis, Nikos, Rowan, A., Nolte, R., Christianen, P. & Canters, G., 2008, In: Proceedings of the National Academy of Sciences USA (PNAS). 105, 9, p. 3250-3255Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
How curved membranes recruit amphipathic helices and protein anchoring motifs
Hatzakis, Nikos, Bhatia, V. K., Larsen, J., Madsen, Kenneth Lindegaard, Bolinger, P., Kunding, A. H., Castillo Leon, J. J., Gether, Ulrik, Hedegård, Per & Stamou, Dimitrios, 2009, In: Nature Chemical Biology. 5, 11, p. 835-841 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
A unifying mechanism accounts for sensing of membrane curvature by BAR domains, amphipathic helices and membrane-anchored proteins
Bhatia, V. K., Hatzakis, Nikos & Stamou, Dimitrios, Jun 2010, In: Seminars in Cell and Developmental Biology. 21, 4, p. 381-390 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Lipid Heterogeneity and Phase Behavior on Phospholipase A(2) Action at the Single Molecule Level
Gudmand, M. J., Rocha, S., Hatzakis, Nikos, Peneva, K., Müllen , K., Stamou, Dimitrios, Uji-I, H., Hofkens , J., Bjørnholm, T. & Heimburg, Thomas Rainer, 5 May 2010, In: Biophysical Journal. 98, 9, p. 1873-82 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Lipid Heterogeneity and Phase Behavior on Phospholipase A2 Action at the Single Molecule Level: Biophysical Journal
Hatzakis, Nikos, 2010, In: Biophysical Society. Annual Meeting. Abstracts.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Optically Induced Linking of Protein and Nanoparticles to Gold Surfaces
Moth-Poulsen, K., Kofod-Hansen, V., S. Kamounah, F., Hatzakis, Nikos, Stamou, Dimitrios, Schaumburg, K. & Christensen, Jørn Bolstad, 2010, In: Bioconjugate Chemistry. 21, p. 1056 1061 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
A discrete number of activity states constitute an efficient mechanism to regulate enzymatic activity
Hatzakis, Nikos, Wei, L., Jorgensen, S. K., Kunding, A., Hedegard, P. & Stamou, Dimitrios, 2011, In: European Biophysics Journal With Biophysics Letters. 40, suppl 1, p. S217 1 p.Research output: Contribution to journal › Journal article › Research
- Published
Regulation of Enzymatic Activity Occurs by Selection of Discrete Activity States
Hatzakis, Nikos, Wei, L., Jorgensen, S. K., Kunding, A. H., Hedegard, P. & Stamou, Dimitrios, 2011, In: Biophysical Journal. 100, 3 suppl 1, p. 194a 1 p.Research output: Contribution to journal › Journal article › Research
- Published
Synergy between membrane-curvature and liquid ordered phase-state effectively sorts amphiphilic protein-anchoring motifs
Larsen, J., Jensen, M. B., Hatzakis, Nikos, Bhatia, V. K. & Stamou, Dimitrios, 2011, In: European Biophysics Journal. 40, Suppl 1, p. S200 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Observation of inhomogeneity in the lipid composition of individual nanoscale liposomes
Larsen, J., Hatzakis, Nikos & Stamou, Dimitrios, 20 Jul 2011, In: Journal of the American Chemical Society. 133, 28, p. 10685-10687 3 p.Research output: Contribution to journal › Letter › Research › peer-review
ID: 6090
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Insights in enzyme functional dynamics and activity regulation by single molecule studies
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Single enzyme experiments reveal a long-lifetime proton leak state in a heme-copper oxidase
Research output: Contribution to journal › Journal article › Research › peer-review
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Links of conformational sampling to functional plasticity and clinical phenotypes by single molecule studies
Research output: Contribution to journal › Conference abstract in journal › Research
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