Nikos Hatzakis

Nikos Hatzakis

Professor


  1. 2001
  2. Oxidation of benzyl alcohols by dimethyldioxirane. The question of concerted versus stepwise mechanisms probed by kinetic isotope effects

    Angelis, Y. S., Hatzakis, Nikos, Smonou, I. & Orfanopoulos, M., 2001, In: Tetrahedron Letters. 42, 22, p. 3753-3756 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2003
  4. Ferulic acid esterase from Humicola Insolens catalyzes enantioselective transesterification of secondary alcohols

    Hatzakis, Nikos, Daphnomili, D. & Smonou, I., 2003, In: Journal of Molecular Catalysis B: Enzymatic. 21, 4-6, p. 309-311 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2004
  6. Enantioselectivity and diastereoselectivity in the transesterification of secondary alcohols mediated by feruloyl esterase from Humicola insolens

    Hatzakis, Nikos & Smonou, I., 2004, In: Tetrahedron Letters. 45, 13, p. 2755-2757 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2005
  8. Functional nano-sized assemblies from amphiphilic biohybrid macromolecules

    Cornelissen, J., Dirks, A., Reynhout, I., Opsteen, J., Hatzakis, Nikos, Sly, J., Rowan, A., van Hest, J. & Nolte, R., 2005, In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.

    Research output: Contribution to journalConference abstract in journalResearch

  9. Preparation of biohybrid amphiphiles via the copper catalysed Huisgen [3 + 2] dipolar cycloaddition reaction

    Dirks, A. J., Van Berkel, S. S., Hatzakis, Nikos, Opsteen, J. A., Van Delft, F. L., Cornelissen, J. J. L. M., Rowan, A. E., Van Hest, J. C. M., Rutjes, F. P. J. T. & Nolte, R. J. M., 7 Sep 2005, In: Chemical Communications. 33, p. 4172-4174 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Asymmetric transesterification of secondary alcohols catalyzed by feruloyl esterase from Humicola insolens

    Hatzakis, Nikos & Smonou, I., 2005, In: Bioorganic Chemistry. 33, 4, p. 325-337 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2006
  12. Bionanoconjugation via click chemistry: The creation of functional hybrids of lipases and gold nanoparticles

    Brennan, J. L., Hatzakis, Nikos, Tshikhudo, T. R., Dirvianskyte, N., Razumas, V., Patkar, S., Vind, J., Svendsen, A., Nolte, R. J. M., Rowan, A. E. & Brust, M., 2006, In: Bioconjugate Chemistry. 17, 6, p. 1373-1375 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Functional biohybrid amphiphiles

    Dirks, A. J., Hatzakis, Nikos, Cornelissen, J. J. L. M. & Nolte, R. J. M., 2006, In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.

    Research output: Contribution to journalConference abstract in journalResearch

  14. Do enzymes sleep and work?

    Engelkamp, H., Hatzakis, Nikos, Hofkens, J., De Schryver, F. C., Nolte, R. J. M. & Rowan, A. E., 2006, In: Chemical Communications. 9, p. 935-940 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    From single to multienzyme assemblies: Do enzymes sleep and work?

    Hatzakis, Nikos, Engelkamp, H., Nolte, R. & Rowan, A., 2006, In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.

    Research output: Contribution to journalJournal articleResearch

  16. Synthesis and single enzyme activity of a clicked lipase-BSA hetero-dimer

    Hatzakis, Nikos, Engelkamp, H., Velonia, K., Hofkens, J., Christianen, P. C. M., Svendsen, A., Patkar, S. A., Vind, J., Maan, J. C., Rowan, A. E. & Nolte, R. J. M., 2006, In: Chemical Communications. 19, p. 2012-2014 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. POLY 391-Assembly strategies for enzyme immobilization

    Lambermon, M., Hendriks, L. J., Schoffelen, S., Vos, M., Hatzakis, Nikos, Carette, N., Rowan, A. E., Cornelissen, J., Michon, T., Sommerdijk, N. A. J. M. & van Hest, J. C. M., 2006, In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.

    Research output: Contribution to journalConference abstract in journalResearch

  18. POLY 553-Biohybrid block copolymer architectures by "click" chemistry

    Opsteen, J. A., Dirks, A. J., van Berkel, S. S., Hatzakis, Nikos, Brinkhuis, R. P., Reijnders, M. E. G. & van Hest, J. C. M., 2006, In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.

    Research output: Contribution to journalConference abstract in journalResearch

  19. 2007
  20. Positional assembly of enzymes in polymersome nanoreactors for cascade reactions

    Vriezema, D. M., Garcia, P. M. L., Oltra, N. S., Hatzakis, Nikos, Kuiper, S. M., Nolte, R. J. M., Rowan, A. E. & van Hest, J. C. M., 2007, In: Angewandte Chemie International Edition. 46, 39, p. 7378-7382 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  21. 2008
  22. Published

    β-Cyclodextrin-appended giant amphiphile: Aggregation to vesicle polymersomes and immobilisation of enzymes

    Felici, M., Marzá-Pérez, M., Hatzakis, Nikos, Nolte, R. J. M. & Feiters, M. C., 2008, In: Chemistry - A European Journal. 14, 32, p. 9914-9920 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The enzyme mechanism of nitrite reductase studied at single-molecule level

    Kuznetsova, S., Zauner, G., Aartsma, T., Engelkamp, H., Hatzakis, Nikos, Rowan, A., Nolte, R., Christianen, P. & Canters, G., 2008, In: Proceedings of the National Academy of Sciences USA (PNAS). 105, 9, p. 3250-3255

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2009
  25. Published

    How curved membranes recruit amphipathic helices and protein anchoring motifs

    Hatzakis, Nikos, Bhatia, V. K., Larsen, J., Madsen, Kenneth Lindegaard, Bolinger, P., Kunding, A. H., Castillo Leon, J. J., Gether, Ulrik, Hedegård, Per & Stamou, Dimitrios, 2009, In: Nature Chemical Biology. 5, 11, p. 835-841 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2010
  27. Published

    A unifying mechanism accounts for sensing of membrane curvature by BAR domains, amphipathic helices and membrane-anchored proteins

    Bhatia, V. K., Hatzakis, Nikos & Stamou, Dimitrios, Jun 2010, In: Seminars in Cell and Developmental Biology. 21, 4, p. 381-390 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Influence of Lipid Heterogeneity and Phase Behavior on Phospholipase A(2) Action at the Single Molecule Level

    Gudmand, M. J., Rocha, S., Hatzakis, Nikos, Peneva, K., Müllen , K., Stamou, Dimitrios, Uji-I, H., Hofkens , J., Bjørnholm, T. & Heimburg, Thomas Rainer, 5 May 2010, In: Biophysical Journal. 98, 9, p. 1873-82 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Influence of Lipid Heterogeneity and Phase Behavior on Phospholipase A2 Action at the Single Molecule Level: Biophysical Journal

    Hatzakis, Nikos, 2010, In: Biophysical Society. Annual Meeting. Abstracts.

    Research output: Contribution to journalConference abstract in journalResearch

  30. Published

    Optically Induced Linking of Protein and Nanoparticles to Gold Surfaces

    Moth-Poulsen, K., Kofod-Hansen, V., S. Kamounah, F., Hatzakis, Nikos, Stamou, Dimitrios, Schaumburg, K. & Christensen, Jørn Bolstad, 2010, In: Bioconjugate Chemistry. 21, p. 1056 1061 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2011
  32. Published

    A discrete number of activity states constitute an efficient mechanism to regulate enzymatic activity

    Hatzakis, Nikos, Wei, L., Jorgensen, S. K., Kunding, A., Hedegard, P. & Stamou, Dimitrios, 2011, In: European Biophysics Journal With Biophysics Letters. 40, suppl 1, p. S217 1 p.

    Research output: Contribution to journalJournal articleResearch

  33. Published

    Regulation of Enzymatic Activity Occurs by Selection of Discrete Activity States

    Hatzakis, Nikos, Wei, L., Jorgensen, S. K., Kunding, A. H., Hedegard, P. & Stamou, Dimitrios, 2011, In: Biophysical Journal. 100, 3 suppl 1, p. 194a 1 p.

    Research output: Contribution to journalJournal articleResearch

  34. Published

    Synergy between membrane-curvature and liquid ordered phase-state effectively sorts amphiphilic protein-anchoring motifs

    Larsen, J., Jensen, M. B., Hatzakis, Nikos, Bhatia, V. K. & Stamou, Dimitrios, 2011, In: European Biophysics Journal. 40, Suppl 1, p. S200 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  35. Published

    Observation of inhomogeneity in the lipid composition of individual nanoscale liposomes

    Larsen, J., Hatzakis, Nikos & Stamou, Dimitrios, 20 Jul 2011, In: Journal of the American Chemical Society. 133, 28, p. 10685-10687 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

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