Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases

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Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases. / Lim, Hooi Ching; Couchman, John Robert.

In: BBA General Subjects, Vol. 1840, No. 8, 18.01.2014, p. 2482–2490.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Lim, HC & Couchman, JR 2014, 'Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases', BBA General Subjects, vol. 1840, no. 8, pp. 2482–2490. https://doi.org/10.1016/j.bbagen.2014.01.018

APA

Lim, H. C., & Couchman, J. R. (2014). Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases. BBA General Subjects, 1840(8), 2482–2490. https://doi.org/10.1016/j.bbagen.2014.01.018

Vancouver

Lim HC, Couchman JR. Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases. BBA General Subjects. 2014 Jan 18;1840(8):2482–2490. https://doi.org/10.1016/j.bbagen.2014.01.018

Author

Lim, Hooi Ching ; Couchman, John Robert. / Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases. In: BBA General Subjects. 2014 ; Vol. 1840, No. 8. pp. 2482–2490.

Bibtex

@article{f0f82adc9de1474a8cebfec0e0f45c76,

title = "Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases",

abstract = "While syndecan-2 is usually considered a mesenchymal transmembrane proteoglycan, it can be upregulated in some tumour cells, such as the malignant breast carcinoma cell line, MDA-MB231. Depletion of this syndecan by siRNA, but not other syndecans, has a marked effect on cell morphology, increasing spreading, microfilament bundle and focal adhesion formation, with reduced cell migration.",

author = "Lim, {Hooi Ching} and Couchman, {John Robert}",

year = "2014",

month = jan,

day = "18",

doi = "10.1016/j.bbagen.2014.01.018",

language = "English",

volume = "1840",

pages = "2482–2490",

journal = "B B A - General Subjects",

issn = "0304-4165",

publisher = "Elsevier",

number = "8",

}

RIS

TY - JOUR

T1 - Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases

AU - Lim, Hooi Ching

AU - Couchman, John Robert

PY - 2014/1/18

Y1 - 2014/1/18

N2 - While syndecan-2 is usually considered a mesenchymal transmembrane proteoglycan, it can be upregulated in some tumour cells, such as the malignant breast carcinoma cell line, MDA-MB231. Depletion of this syndecan by siRNA, but not other syndecans, has a marked effect on cell morphology, increasing spreading, microfilament bundle and focal adhesion formation, with reduced cell migration.

AB - While syndecan-2 is usually considered a mesenchymal transmembrane proteoglycan, it can be upregulated in some tumour cells, such as the malignant breast carcinoma cell line, MDA-MB231. Depletion of this syndecan by siRNA, but not other syndecans, has a marked effect on cell morphology, increasing spreading, microfilament bundle and focal adhesion formation, with reduced cell migration.

U2 - 10.1016/j.bbagen.2014.01.018

DO - 10.1016/j.bbagen.2014.01.018

M3 - Journal article

C2 - 24447566

VL - 1840

SP - 2482

EP - 2490

JO - B B A - General Subjects

JF - B B A - General Subjects

SN - 0304-4165

IS - 8

ER -

ID: 109872808