Ny markør ved trombotisk trombocytopenisk purpura.
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Ny markør ved trombotisk trombocytopenisk purpura. / Gøtze, Jens Peter; Hillarp, Andreas; Lindblom, Anders; Björk, Peter; Strandberg, Karin; Nielsen, Lars Bo.
In: Ugeskrift for læger, Vol. 170, No. 33, 2008, p. 2446-9.Research output: Contribution to journal › Journal article › peer-review
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TY - JOUR
T1 - Ny markør ved trombotisk trombocytopenisk purpura.
AU - Gøtze, Jens Peter
AU - Hillarp, Andreas
AU - Lindblom, Anders
AU - Björk, Peter
AU - Strandberg, Karin
AU - Nielsen, Lars Bo
N1 - Keywords: ADAM Proteins; Biological Markers; Diagnosis, Differential; Humans; Purpura, Thrombotic Thrombocytopenic; von Willebrand Factor
PY - 2008
Y1 - 2008
N2 - Thrombotic microangiopathy can be caused by several conditions which are difficult to diagnose from the clinical presentation alone. Deficient enzyme activity of a newly-discovered enzyme, ADAMTS-13, can lead to thrombotic thrombocytopenic purpura (TTP). Lack of ADAMTS-13 activity causes increased concentrations of high molecular weight von Willebrand factor forms and increased platelet aggregation. Measurement of ADAMTS-13 activity is useful for the diagnosis of TTP and may also be relevant as a prognostic test for recurrent TTP. Udgivelsesdato: 2008-Aug-11
AB - Thrombotic microangiopathy can be caused by several conditions which are difficult to diagnose from the clinical presentation alone. Deficient enzyme activity of a newly-discovered enzyme, ADAMTS-13, can lead to thrombotic thrombocytopenic purpura (TTP). Lack of ADAMTS-13 activity causes increased concentrations of high molecular weight von Willebrand factor forms and increased platelet aggregation. Measurement of ADAMTS-13 activity is useful for the diagnosis of TTP and may also be relevant as a prognostic test for recurrent TTP. Udgivelsesdato: 2008-Aug-11
M3 - Tidsskriftartikel
C2 - 18761827
VL - 170
SP - 2446
EP - 2449
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 33
ER -
ID: 8466128