Wounds in chronic leg oedema
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Wounds in chronic leg oedema. / Burian, Ewa Anna; Karlsmark, Tonny; Nørregaard, Susan; Kirketerp-Møller, Klaus; Kirsner, Robert Scott; Franks, Peter John; Quéré, Isabelle; Moffatt, Christine Joy.
In: International Wound Journal, Vol. 19, No. 2, 2022, p. 411-425.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Wounds in chronic leg oedema
AU - Burian, Ewa Anna
AU - Karlsmark, Tonny
AU - Nørregaard, Susan
AU - Kirketerp-Møller, Klaus
AU - Kirsner, Robert Scott
AU - Franks, Peter John
AU - Quéré, Isabelle
AU - Moffatt, Christine Joy
N1 - Publisher Copyright: © 2021 The Authors. International Wound Journal published by Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd.
PY - 2022
Y1 - 2022
N2 - Wounds and chronic oedema are common disorders, but rarely studied together. The objective of this cross-sectional study was to investigate the point-prevalence and risk factors of wounds on the leg, in chronic leg oedema. Forty sites in nine countries were included. Of 7077 patients with chronic leg oedema, 12.70% had wounds. Independent risk factors were: peripheral arterial disease (odds ratio (OR) 4.87, 95% confidence intervals (CI) 3.63-6.52), cellulitis within the past 12 months (OR 2.69, 95% CI 2.25-3.21), secondary lymphoedema (OR 2.64, 95% CI 1.93-3.60), being male (OR 2.08, 95% CI 1.78-2.44), being over 85 years of age (OR 1.80, 95% CI 1.23-2.62), underweight (OR 1.79, 95% CI 1.14-2.79), bed bound (OR 1.79, 95% CI 1.01-3.16), chair bound (OR 1.52, 95% CI 1.18-1.97), diabetes (OR 1.47, 95% CI 1.23-1.77), and walking with aid (OR 1·41, 95% CI 1.17-1.69). 43.22% of those with wounds had clinically defined well-controlled oedema, associated with a significantly lower risk of wounds (OR 0.50, 95% CI 0.42-0.58, P <.001). Hard/fibrotic tissue (OR 1.71, 95% CI 1.19-2.48), and a positive Stemmers sign (OR 1.57, 95% CI 1.05-2.35) were associated with wounds. The study reinforces the importance of measures to control oedema, as controlled swelling was associated with a 50% lower risk of wounds.
AB - Wounds and chronic oedema are common disorders, but rarely studied together. The objective of this cross-sectional study was to investigate the point-prevalence and risk factors of wounds on the leg, in chronic leg oedema. Forty sites in nine countries were included. Of 7077 patients with chronic leg oedema, 12.70% had wounds. Independent risk factors were: peripheral arterial disease (odds ratio (OR) 4.87, 95% confidence intervals (CI) 3.63-6.52), cellulitis within the past 12 months (OR 2.69, 95% CI 2.25-3.21), secondary lymphoedema (OR 2.64, 95% CI 1.93-3.60), being male (OR 2.08, 95% CI 1.78-2.44), being over 85 years of age (OR 1.80, 95% CI 1.23-2.62), underweight (OR 1.79, 95% CI 1.14-2.79), bed bound (OR 1.79, 95% CI 1.01-3.16), chair bound (OR 1.52, 95% CI 1.18-1.97), diabetes (OR 1.47, 95% CI 1.23-1.77), and walking with aid (OR 1·41, 95% CI 1.17-1.69). 43.22% of those with wounds had clinically defined well-controlled oedema, associated with a significantly lower risk of wounds (OR 0.50, 95% CI 0.42-0.58, P <.001). Hard/fibrotic tissue (OR 1.71, 95% CI 1.19-2.48), and a positive Stemmers sign (OR 1.57, 95% CI 1.05-2.35) were associated with wounds. The study reinforces the importance of measures to control oedema, as controlled swelling was associated with a 50% lower risk of wounds.
UR - http://www.scopus.com/inward/record.url?scp=85109989434&partnerID=8YFLogxK
U2 - 10.1111/iwj.13642
DO - 10.1111/iwj.13642
M3 - Journal article
C2 - 34258856
AN - SCOPUS:85109989434
VL - 19
SP - 411
EP - 425
JO - International Wound Journal
JF - International Wound Journal
SN - 1742-4801
IS - 2
ER -
ID: 320674842