Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people
Research output: Contribution to journal › Journal article › Research › peer-review
A meta-analysis of 21 genome-wide association studies identified 11 novel genetic loci implicated in fasting glucose homeostasis. We aimed to evaluate the impact of these variants on insulin release and insulin sensitivity estimated from OGTTs.
| Original language | English |
|---|---|
| Journal | Diabetologia |
| Volume | 53 |
| Issue number | 8 |
| Pages (from-to) | 1647-55 |
| Number of pages | 9 |
| ISSN | 0012-186X |
| DOIs | |
| Publication status | Published - 1 Aug 2010 |
- Denmark, Diacylglycerol Kinase, Female, Genetic Loci, Genetic Predisposition to Disease, Genome-Wide Association Study, Genotype, Glucose, Humans, Insulin-Secreting Cells, Male, Middle Aged, Receptors, Adrenergic, alpha-2, Transcription Factors
Research areas
ID: 33501934