Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania

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Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania. / Mohammed, Asia; Ndaro, Arnold; Kalinga, Akili; Manjurano, Alphaxard; Mosha, Jackline F; Mosha, Dominick F; van Zwetselaar, Marco; Koenderink, Jan B; Mosha, Frank W; Alifrangis, Michael; Reyburn, Hugh; Roper, Cally; Kavishe, Reginald A.

In: Malaria Journal, Vol. 12, No. 1, 14.11.2013, p. 415.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Mohammed, A, Ndaro, A, Kalinga, A, Manjurano, A, Mosha, JF, Mosha, DF, van Zwetselaar, M, Koenderink, JB, Mosha, FW, Alifrangis, M, Reyburn, H, Roper, C & Kavishe, RA 2013, 'Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania', Malaria Journal, vol. 12, no. 1, pp. 415. https://doi.org/10.1186/1475-2875-12-415

APA

Mohammed, A., Ndaro, A., Kalinga, A., Manjurano, A., Mosha, J. F., Mosha, D. F., van Zwetselaar, M., Koenderink, J. B., Mosha, F. W., Alifrangis, M., Reyburn, H., Roper, C., & Kavishe, R. A. (2013). Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania. Malaria Journal, 12(1), 415. https://doi.org/10.1186/1475-2875-12-415

Vancouver

Mohammed A, Ndaro A, Kalinga A, Manjurano A, Mosha JF, Mosha DF et al. Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania. Malaria Journal. 2013 Nov 14;12(1):415. https://doi.org/10.1186/1475-2875-12-415

Author

Mohammed, Asia ; Ndaro, Arnold ; Kalinga, Akili ; Manjurano, Alphaxard ; Mosha, Jackline F ; Mosha, Dominick F ; van Zwetselaar, Marco ; Koenderink, Jan B ; Mosha, Frank W ; Alifrangis, Michael ; Reyburn, Hugh ; Roper, Cally ; Kavishe, Reginald A. / Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania. In: Malaria Journal. 2013 ; Vol. 12, No. 1. pp. 415.

Bibtex

@article{130b2fc9c8094ee6bad1653ea88bea13,
title = "Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania",
abstract = "Plasmodium falciparum resistance to anti-malarial drugs remains a major obstacle to the control of malaria. In 2001 Tanzania replaced chloroquine (CQ) with sulphadoxine-pyrimethamine (SP) as first-line drug, which in turn was replaced by artemisinin combination therapy in 2006. SP has however, continued to be used in intermittent preventive treatment of malaria in pregnancy (IPTp) despite reports of high levels of resistance to SP due to the lack of alternatives to SP for IPTp. Recent reports have indicated recovery of CQ-susceptibility in Malawi, Kenya, Mozambique, and Tanzania based on the prevalence of wild types at codon 76 of the Pfcrt gene in indigenous P. falciparum populations. The current prevalence of this Pfcrt-76 CQ resistance marker from six regions of Tanzania mainland is hereby reported.",
author = "Asia Mohammed and Arnold Ndaro and Akili Kalinga and Alphaxard Manjurano and Mosha, {Jackline F} and Mosha, {Dominick F} and {van Zwetselaar}, Marco and Koenderink, {Jan B} and Mosha, {Frank W} and Michael Alifrangis and Hugh Reyburn and Cally Roper and Kavishe, {Reginald A}",
year = "2013",
month = nov,
day = "14",
doi = "10.1186/1475-2875-12-415",
language = "English",
volume = "12",
pages = "415",
journal = "Malaria Journal",
issn = "1475-2875",
publisher = "BioMed Central",
number = "1",

}

RIS

TY - JOUR

T1 - Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania

AU - Mohammed, Asia

AU - Ndaro, Arnold

AU - Kalinga, Akili

AU - Manjurano, Alphaxard

AU - Mosha, Jackline F

AU - Mosha, Dominick F

AU - van Zwetselaar, Marco

AU - Koenderink, Jan B

AU - Mosha, Frank W

AU - Alifrangis, Michael

AU - Reyburn, Hugh

AU - Roper, Cally

AU - Kavishe, Reginald A

PY - 2013/11/14

Y1 - 2013/11/14

N2 - Plasmodium falciparum resistance to anti-malarial drugs remains a major obstacle to the control of malaria. In 2001 Tanzania replaced chloroquine (CQ) with sulphadoxine-pyrimethamine (SP) as first-line drug, which in turn was replaced by artemisinin combination therapy in 2006. SP has however, continued to be used in intermittent preventive treatment of malaria in pregnancy (IPTp) despite reports of high levels of resistance to SP due to the lack of alternatives to SP for IPTp. Recent reports have indicated recovery of CQ-susceptibility in Malawi, Kenya, Mozambique, and Tanzania based on the prevalence of wild types at codon 76 of the Pfcrt gene in indigenous P. falciparum populations. The current prevalence of this Pfcrt-76 CQ resistance marker from six regions of Tanzania mainland is hereby reported.

AB - Plasmodium falciparum resistance to anti-malarial drugs remains a major obstacle to the control of malaria. In 2001 Tanzania replaced chloroquine (CQ) with sulphadoxine-pyrimethamine (SP) as first-line drug, which in turn was replaced by artemisinin combination therapy in 2006. SP has however, continued to be used in intermittent preventive treatment of malaria in pregnancy (IPTp) despite reports of high levels of resistance to SP due to the lack of alternatives to SP for IPTp. Recent reports have indicated recovery of CQ-susceptibility in Malawi, Kenya, Mozambique, and Tanzania based on the prevalence of wild types at codon 76 of the Pfcrt gene in indigenous P. falciparum populations. The current prevalence of this Pfcrt-76 CQ resistance marker from six regions of Tanzania mainland is hereby reported.

U2 - 10.1186/1475-2875-12-415

DO - 10.1186/1475-2875-12-415

M3 - Journal article

C2 - 24225406

VL - 12

SP - 415

JO - Malaria Journal

JF - Malaria Journal

SN - 1475-2875

IS - 1

ER -

ID: 80636422