The cardiovascular challenges in giraffes

Research output: Contribution to journal › Review › Research › peer-review

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The cardiovascular challenges in giraffes. / Aalkjaer, Christian; Wang, Tobias.

In: Journal of Muscle Research and Cell Motility, Vol. 44, 2023, p. 53–60.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Aalkjaer, C & Wang, T 2023, 'The cardiovascular challenges in giraffes', Journal of Muscle Research and Cell Motility, vol. 44, pp. 53–60. https://doi.org/10.1007/s10974-022-09626-0

APA

Aalkjaer, C., & Wang, T. (2023). The cardiovascular challenges in giraffes. Journal of Muscle Research and Cell Motility, 44, 53–60. https://doi.org/10.1007/s10974-022-09626-0

Vancouver

Aalkjaer C, Wang T. The cardiovascular challenges in giraffes. Journal of Muscle Research and Cell Motility. 2023;44:53–60. https://doi.org/10.1007/s10974-022-09626-0

Author

Aalkjaer, Christian ; Wang, Tobias. / The cardiovascular challenges in giraffes. In: Journal of Muscle Research and Cell Motility. 2023 ; Vol. 44. pp. 53–60.

Bibtex

@article{9ed24724d05e428b87e31f69c386fa6b,
title = "The cardiovascular challenges in giraffes",
abstract = "Giraffes are the highest living animals on Earth and therefore are challenged by gravity more than any other species. In particular the cardiovascular system needs to adapt to this challenge. Giraffes have a mean blood pressure around 200 mmHg, which ensures a mean arterial pressure near the head of 100 mmHg when the giraffe is standing with the neck in a near vertical position. This immediately raises several questions. How do giraffes avoid edema in the legs where the arterial pressure is 300 mmHg or higher? How does the heart produce a pressure of 200 mmHg, and what is the energy required for this endeavor? How can the kidney tolerate a pressure of about 200 mmHg and does this mean that giraffes have a high glomerular filtration rate? What is the arterial pressure in the head of giraffes when they drink, and how is perfusion of the brain maintained when they lift their head after drinking? In this short review, we present some answers to these questions.",
keywords = "Edema, Renal function, Vascular structure, Cerebral perfusion, Cardiac output, BLOOD-PRESSURE, SYMPATHETIC INNERVATION, ARTERIAL SYSTEM, KIDNEY",
author = "Christian Aalkjaer and Tobias Wang",
year = "2023",
doi = "10.1007/s10974-022-09626-0",
language = "English",
volume = "44",
pages = "53–60",
journal = "Journal of Muscle Research and Cell Motility",
issn = "0142-4319",
publisher = "Springer",

}

RIS

TY - JOUR

T1 - The cardiovascular challenges in giraffes

AU - Aalkjaer, Christian

AU - Wang, Tobias

PY - 2023

Y1 - 2023

N2 - Giraffes are the highest living animals on Earth and therefore are challenged by gravity more than any other species. In particular the cardiovascular system needs to adapt to this challenge. Giraffes have a mean blood pressure around 200 mmHg, which ensures a mean arterial pressure near the head of 100 mmHg when the giraffe is standing with the neck in a near vertical position. This immediately raises several questions. How do giraffes avoid edema in the legs where the arterial pressure is 300 mmHg or higher? How does the heart produce a pressure of 200 mmHg, and what is the energy required for this endeavor? How can the kidney tolerate a pressure of about 200 mmHg and does this mean that giraffes have a high glomerular filtration rate? What is the arterial pressure in the head of giraffes when they drink, and how is perfusion of the brain maintained when they lift their head after drinking? In this short review, we present some answers to these questions.

AB - Giraffes are the highest living animals on Earth and therefore are challenged by gravity more than any other species. In particular the cardiovascular system needs to adapt to this challenge. Giraffes have a mean blood pressure around 200 mmHg, which ensures a mean arterial pressure near the head of 100 mmHg when the giraffe is standing with the neck in a near vertical position. This immediately raises several questions. How do giraffes avoid edema in the legs where the arterial pressure is 300 mmHg or higher? How does the heart produce a pressure of 200 mmHg, and what is the energy required for this endeavor? How can the kidney tolerate a pressure of about 200 mmHg and does this mean that giraffes have a high glomerular filtration rate? What is the arterial pressure in the head of giraffes when they drink, and how is perfusion of the brain maintained when they lift their head after drinking? In this short review, we present some answers to these questions.

KW - Edema

KW - Renal function

KW - Vascular structure

KW - Cerebral perfusion

KW - Cardiac output

KW - BLOOD-PRESSURE

KW - SYMPATHETIC INNERVATION

KW - ARTERIAL SYSTEM

KW - KIDNEY

U2 - 10.1007/s10974-022-09626-0

DO - 10.1007/s10974-022-09626-0

M3 - Review

C2 - 35879488

VL - 44

SP - 53

EP - 60

JO - Journal of Muscle Research and Cell Motility

JF - Journal of Muscle Research and Cell Motility

SN - 0142-4319

ER -

ID: 316691439