Synthesis and Antimicrobial Properties of a Ciprofloxacin and PAMAM-dendrimer Conjugate
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- molecules-25-01389-v2
Final published version, 975 KB, PDF document
Infections caused by bacteria resistant to antibiotics are an increasing problem. Multivalent antibiotics could be a solution. In the present study, a covalent conjugate between Ciprofloxacin and a G0-PAMAM dendrimer has been synthesized and tested against clinically relevant Gram-positive and Gram-negative bacteria. The conjugate has antimicrobial activity and there is a positive dendritic effect compared to Ciprofloxacin itself.
Original language | English |
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Article number | 1389 |
Journal | Molecules |
Volume | 25 |
Issue number | 6 |
Pages (from-to) | 1-13 |
ISSN | 1420-3049 |
DOIs | |
Publication status | Published - 2020 |
- Antimicrobial compounds, Ciprofloxacin, Dendrimers
Research areas
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ID: 240005690