Syndecan-4 and focal adhesion function.
Research output: Contribution to journal › Journal article › Research › peer-review
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Syndecan-4 and focal adhesion function. / Woods, A; Couchman, J R.
In: Current Opinion in Cell Biology, Vol. 13, No. 5, 2001, p. 578-83.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Syndecan-4 and focal adhesion function.
AU - Woods, A
AU - Couchman, J R
N1 - Keywords: Animals; Focal Adhesions; Integrins; Membrane Glycoproteins; Mice; Mice, Knockout; Models, Biological; Neovascularization, Pathologic; Protein Structure, Tertiary; Proteoglycans; Signal Transduction; Syndecan-4; Wound Healing
PY - 2001
Y1 - 2001
N2 - Two groups have now reported the viability of mice that lack syndecan-4. These mice have wound healing/angiogenesis problems, and fibroblasts from these animals differ in adhesion and migration from normal. This is consistent with recent in vitro data indicating a need for signaling via syndecan-4 for focal adhesion formation, and reports that overexpression of proteins that bind syndecan-4 can modify cell adhesion and migration.
AB - Two groups have now reported the viability of mice that lack syndecan-4. These mice have wound healing/angiogenesis problems, and fibroblasts from these animals differ in adhesion and migration from normal. This is consistent with recent in vitro data indicating a need for signaling via syndecan-4 for focal adhesion formation, and reports that overexpression of proteins that bind syndecan-4 can modify cell adhesion and migration.
M3 - Journal article
C2 - 11544026
VL - 13
SP - 578
EP - 583
JO - Current Opinion in Cell Biology
JF - Current Opinion in Cell Biology
SN - 0955-0674
IS - 5
ER -
ID: 5162938