Syndecan proteoglycans and cell adhesion.
Research output: Contribution to journal › Journal article › Research › peer-review
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Syndecan proteoglycans and cell adhesion. / Woods, A; Oh, E S; Couchman, J R.
In: Matrix Biology, Vol. 17, No. 7, 1998, p. 477-83.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Syndecan proteoglycans and cell adhesion.
AU - Woods, A
AU - Oh, E S
AU - Couchman, J R
N1 - Keywords: Amino Acid Sequence; Animals; Cell Adhesion; Cell Membrane; Cytoplasm; Cytoskeleton; Heparitin Sulfate; Humans; Membrane Glycoproteins; Molecular Sequence Data; Proteoglycans; Syndecans
PY - 1998
Y1 - 1998
N2 - It is now becoming clear that a family of transmembrane proteoglycans, the syndecans, have important roles in cell adhesion. They participate through binding of matrix ligand to their glycosaminoglycan chains, clustering, and the induction of signaling cascades to modify the internal microfilament organization. Syndecans can modulate the type of adhesive responses induced by other matrix ligand-receptor interactions, such as those involving the integrins, and so contribute to the control of cell morphology, adhesion and migration.
AB - It is now becoming clear that a family of transmembrane proteoglycans, the syndecans, have important roles in cell adhesion. They participate through binding of matrix ligand to their glycosaminoglycan chains, clustering, and the induction of signaling cascades to modify the internal microfilament organization. Syndecans can modulate the type of adhesive responses induced by other matrix ligand-receptor interactions, such as those involving the integrins, and so contribute to the control of cell morphology, adhesion and migration.
M3 - Journal article
C2 - 9881599
VL - 17
SP - 477
EP - 483
JO - Matrix Biology
JF - Matrix Biology
SN - 0945-053X
IS - 7
ER -
ID: 5164472