Sygdomme og tilstande der påvirker spytkirtlerne og deres funktion
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Sygdomme og tilstande der påvirker spytkirtlerne og deres funktion. / Pedersen, Anne Marie Lynge; Skarstein, Kathrine; Çevik-Aras, Hülya ; Kullaa, Arja M. ; Laine, Hanna ; Liaaen Jensen, Janicke .
In: Norske Tannlegeforenings Tidende, Vol. 134, No. 1, 2024, p. 28-37.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Sygdomme og tilstande der påvirker spytkirtlerne og deres funktion
AU - Pedersen, Anne Marie Lynge
AU - Skarstein, Kathrine
AU - Çevik-Aras, Hülya
AU - Kullaa, Arja M.
AU - Laine, Hanna
AU - Liaaen Jensen, Janicke
PY - 2024
Y1 - 2024
N2 - Salivary gland hypofunction (objective evidence of diminished sa-livary output) and xerostomia (the subjective sensation of dry mouth)are common conditions. Patients with salivary gland hypofunctionand altered saliva composition are at increased risk for developingcaries, oral fungal infections, oral mucosal changes and debilitatingsymptoms, swallowing problems, and diminished or altered taste.The most prominent cause of xerostomia and salivary gland hy-pofunction is the intake of medications interfering with the nervousregulation of salivary secretion. Radiotherapy for cancer in the headand neck region often leads to permanent and severe xerostomia and salivary gland hypofunction due to degeneration of the salivary glandtissue involved in the radiation field. Sjögren’s syndrome, an autoim-mune disease affecting exocrine glands, causes permanent xerosto-mia and hyposalivation due to immune-mediated structural changesin the salivary glands. Ageing may also be associated with structuralchanges in the salivary glands that can influence the functions of sa-liva. This article reviews the aetiopathogenesis, clinical manifesta-tions, diagnosis, and management of conditions with salivary glandhypofunction, common salivary gland diseases (mucous cysts andsialoliths) and salivary gland tumours.
AB - Salivary gland hypofunction (objective evidence of diminished sa-livary output) and xerostomia (the subjective sensation of dry mouth)are common conditions. Patients with salivary gland hypofunctionand altered saliva composition are at increased risk for developingcaries, oral fungal infections, oral mucosal changes and debilitatingsymptoms, swallowing problems, and diminished or altered taste.The most prominent cause of xerostomia and salivary gland hy-pofunction is the intake of medications interfering with the nervousregulation of salivary secretion. Radiotherapy for cancer in the headand neck region often leads to permanent and severe xerostomia and salivary gland hypofunction due to degeneration of the salivary glandtissue involved in the radiation field. Sjögren’s syndrome, an autoim-mune disease affecting exocrine glands, causes permanent xerosto-mia and hyposalivation due to immune-mediated structural changesin the salivary glands. Ageing may also be associated with structuralchanges in the salivary glands that can influence the functions of sa-liva. This article reviews the aetiopathogenesis, clinical manifesta-tions, diagnosis, and management of conditions with salivary glandhypofunction, common salivary gland diseases (mucous cysts andsialoliths) and salivary gland tumours.
U2 - 10.56373/2024-1-6
DO - 10.56373/2024-1-6
M3 - Review
VL - 134
SP - 28
EP - 37
JO - Norske Tannlegeforenings Tidende
JF - Norske Tannlegeforenings Tidende
SN - 0029-2303
IS - 1
ER -
ID: 377707137