Soft tissue myoepithelial carcinoma—a case report with molecular and electron microscopic analysis
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Soft tissue myoepithelial carcinoma—a case report with molecular and electron microscopic analysis. / Wernheden, Erika; Venzo, Alessandro; Daugaard, Søren; Loya, Anand C.
In: APMIS, Vol. 129, No. 4, 04.2021, p. 232-236.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Soft tissue myoepithelial carcinoma—a case report with molecular and electron microscopic analysis
AU - Wernheden, Erika
AU - Venzo, Alessandro
AU - Daugaard, Søren
AU - Loya, Anand C.
N1 - Publisher Copyright: © 2020 APMIS. Published by John Wiley & Sons Ltd
PY - 2021/4
Y1 - 2021/4
N2 - Myoepithelial tumors are rare neoplasms that primarily occur in the salivary gland but over the last decade have also been described in other locations, including soft tissue. Myoepithelial carcinoma of soft tissue has shown to have a recurrence rate of 39–42% and distant metastases in 32–53% of patients. The only known predictor of malignancy in soft tissue myoepithelial tumors described is cytologic atypia. There are no other validated criteria for differentiating benign and malignant tumors, neither for grading nor for standard of care for these tumor types. Herein, we present a case of myoepithelial carcinoma of inguinal soft tissue in a 37-year male. We also describe the molecular and previously sparingly described detailed electron microscopic features of this case.
AB - Myoepithelial tumors are rare neoplasms that primarily occur in the salivary gland but over the last decade have also been described in other locations, including soft tissue. Myoepithelial carcinoma of soft tissue has shown to have a recurrence rate of 39–42% and distant metastases in 32–53% of patients. The only known predictor of malignancy in soft tissue myoepithelial tumors described is cytologic atypia. There are no other validated criteria for differentiating benign and malignant tumors, neither for grading nor for standard of care for these tumor types. Herein, we present a case of myoepithelial carcinoma of inguinal soft tissue in a 37-year male. We also describe the molecular and previously sparingly described detailed electron microscopic features of this case.
KW - Myoepithelial carcinoma
KW - myoepithelioma
KW - soft tissue neoplasm
U2 - 10.1111/apm.13105
DO - 10.1111/apm.13105
M3 - Journal article
C2 - 33336464
AN - SCOPUS:85099100678
VL - 129
SP - 232
EP - 236
JO - A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica
JF - A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica
SN - 0903-4641
IS - 4
ER -
ID: 280238531