TY - JOUR

T1 - Sinonasal inflammation in COPD

T2 - a systematic review

AU - Håkansson, Kåre

AU - Konge, Lars

AU - Thomsen, Sf

AU - Backer, V

AU - Buchwald, Christian von

PY - 2013

Y1 - 2013

N2 - In this review we demonstrate that patients with chronic obstructive pulmonary disease (COPD) frequently report sinonasal symptoms. Furthermore, we present evidence that smoking on its own can cause nasal disease, and that in COPD patients, nasal inflammation mimics that of the bronchi. All this evidence suggests that COPD related sinonasal disease does exist and that smoking on its own rather than systemic inflammation triggers the condition. However, COPD related sinonasal disease remains to be characterized in terms of symptoms and endoscopic findings. In addition, more studies are needed to quantify the negative impact of sinonasal symptoms on the quality of life in COPD patients.

AB - In this review we demonstrate that patients with chronic obstructive pulmonary disease (COPD) frequently report sinonasal symptoms. Furthermore, we present evidence that smoking on its own can cause nasal disease, and that in COPD patients, nasal inflammation mimics that of the bronchi. All this evidence suggests that COPD related sinonasal disease does exist and that smoking on its own rather than systemic inflammation triggers the condition. However, COPD related sinonasal disease remains to be characterized in terms of symptoms and endoscopic findings. In addition, more studies are needed to quantify the negative impact of sinonasal symptoms on the quality of life in COPD patients.

U2 - 10.1183/09031936.00119712

DO - 10.1183/09031936.00119712

M3 - Journal article

C2 - 23100505

JO - The European Respiratory Journal

JF - The European Respiratory Journal

SN - 0903-1936

ER -