Short mandible – a possible risk factor for cleft palate with/without a cleft lip

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Structured Abstract: Objectives: To estimate the influence of a short mandible on the risk of developing a cleft palate with/without a cleft lip (CP). Setting and sample population: The retrospective sample consisted of 115 2-month-old Danish infants with CP, and 70 control infants with unilateral incomplete cleft lip (UICL). Material and Methods: Cephalometric X-rays were obtained. Mandibular length (Lm) was measured and corrected for body length (Lb) to remove influence of varying body length in the sample. Logistic regression was applied to the corrected mandibular length (Lmc) to calculate the risk of having a cleft palate. Results: The mean mandibular length in the group with CP was about 4 mm shorter than in the control group. Odds ratio (OR) was calculated to be 0.58 (95% confidence interval 0.48-0.68), implying that an individual's risk of cleft palate with/without a cleft lip increases about 50% per mm decrease in mandibular length. Conclusions: A special facial type including a short mandible is a possible risk factor for cleft palate, and it was found that the risk of cleft palate increases 58% per mm decreases in mandibular length.

Original languageEnglish
JournalOrthodontics & Craniofacial Research
Volume17
Issue number2
Pages (from-to)106-114
Number of pages9
ISSN1601-6335
DOIs
Publication statusPublished - May 2014

    Research areas

  • Cleft palate, Mandible, Risk factor

ID: 120585360