Serum antibodies to Bacteroides species in chronic inflammatory bowel disease

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Serum antibodies to Bacteroides species in chronic inflammatory bowel disease. / Tvede, M; Bondesen, S; Nielsen, O H; Rasmussen, S N.

In: Scandinavian Journal of Gastroenterology, Vol. 18, No. 6, 1983, p. 783-9.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Tvede, M, Bondesen, S, Nielsen, OH & Rasmussen, SN 1983, 'Serum antibodies to Bacteroides species in chronic inflammatory bowel disease', Scandinavian Journal of Gastroenterology, vol. 18, no. 6, pp. 783-9. https://doi.org/10.3109/00365528309182095

APA

Tvede, M., Bondesen, S., Nielsen, O. H., & Rasmussen, S. N. (1983). Serum antibodies to Bacteroides species in chronic inflammatory bowel disease. Scandinavian Journal of Gastroenterology, 18(6), 783-9. https://doi.org/10.3109/00365528309182095

Vancouver

Tvede M, Bondesen S, Nielsen OH, Rasmussen SN. Serum antibodies to Bacteroides species in chronic inflammatory bowel disease. Scandinavian Journal of Gastroenterology. 1983;18(6):783-9. https://doi.org/10.3109/00365528309182095

Author

Tvede, M ; Bondesen, S ; Nielsen, O H ; Rasmussen, S N. / Serum antibodies to Bacteroides species in chronic inflammatory bowel disease. In: Scandinavian Journal of Gastroenterology. 1983 ; Vol. 18, No. 6. pp. 783-9.

Bibtex

@article{1d8e01f9b68e4d68a465cbca0a2f20a3,
title = "Serum antibodies to Bacteroides species in chronic inflammatory bowel disease",
abstract = "It has been proposed that the presence of elevated serum titres against various Bacteroides species among patients with chronic inflammatory bowel disease (CIBD) may yield aetiological, pathogenic, or prognostic information. Using a crossed immunoelectrophoretic method, we investigated circulating antibodies against four Bacteroides species in 122 patients with CIBD (80 with ulcerative colitis (UC) and 42 with Crohn's disease (CD)) and in 32 patients with the irritable colon syndrome. In this cross-sectional study we found raised titre scores (greater than 0) among 26% of the patients with CD, among 46% of the patients with UC, and among 34% of the patients with the irritable colon syndrome. These differences are not significant. There were no correlations between the antibody titres and the duration of the disease, the clinical disease activity, or the site of the disease. Furthermore, the antibody titres yielded no prognostic information as to the necessity of surgery--that is, colectomy and/or small-bowel resection.",
keywords = "Adolescent, Adult, Aged, Antibodies, Bacterial/analysis, Bacteroides/immunology, Bacteroides fragilis/immunology, Chronic Disease, Colitis, Ulcerative/immunology, Colonic Diseases, Functional/immunology, Crohn Disease/immunology, Humans, Immunoelectrophoresis, Middle Aged, Prospective Studies, Time Factors",
author = "M Tvede and S Bondesen and Nielsen, {O H} and Rasmussen, {S N}",
year = "1983",
doi = "10.3109/00365528309182095",
language = "English",
volume = "18",
pages = "783--9",
journal = "Scandinavian Journal of Gastroenterology. Supplement",
issn = "0085-5928",
publisher = "Taylor & Francis",
number = "6",

}

RIS

TY - JOUR

T1 - Serum antibodies to Bacteroides species in chronic inflammatory bowel disease

AU - Tvede, M

AU - Bondesen, S

AU - Nielsen, O H

AU - Rasmussen, S N

PY - 1983

Y1 - 1983

N2 - It has been proposed that the presence of elevated serum titres against various Bacteroides species among patients with chronic inflammatory bowel disease (CIBD) may yield aetiological, pathogenic, or prognostic information. Using a crossed immunoelectrophoretic method, we investigated circulating antibodies against four Bacteroides species in 122 patients with CIBD (80 with ulcerative colitis (UC) and 42 with Crohn's disease (CD)) and in 32 patients with the irritable colon syndrome. In this cross-sectional study we found raised titre scores (greater than 0) among 26% of the patients with CD, among 46% of the patients with UC, and among 34% of the patients with the irritable colon syndrome. These differences are not significant. There were no correlations between the antibody titres and the duration of the disease, the clinical disease activity, or the site of the disease. Furthermore, the antibody titres yielded no prognostic information as to the necessity of surgery--that is, colectomy and/or small-bowel resection.

AB - It has been proposed that the presence of elevated serum titres against various Bacteroides species among patients with chronic inflammatory bowel disease (CIBD) may yield aetiological, pathogenic, or prognostic information. Using a crossed immunoelectrophoretic method, we investigated circulating antibodies against four Bacteroides species in 122 patients with CIBD (80 with ulcerative colitis (UC) and 42 with Crohn's disease (CD)) and in 32 patients with the irritable colon syndrome. In this cross-sectional study we found raised titre scores (greater than 0) among 26% of the patients with CD, among 46% of the patients with UC, and among 34% of the patients with the irritable colon syndrome. These differences are not significant. There were no correlations between the antibody titres and the duration of the disease, the clinical disease activity, or the site of the disease. Furthermore, the antibody titres yielded no prognostic information as to the necessity of surgery--that is, colectomy and/or small-bowel resection.

KW - Adolescent

KW - Adult

KW - Aged

KW - Antibodies, Bacterial/analysis

KW - Bacteroides/immunology

KW - Bacteroides fragilis/immunology

KW - Chronic Disease

KW - Colitis, Ulcerative/immunology

KW - Colonic Diseases, Functional/immunology

KW - Crohn Disease/immunology

KW - Humans

KW - Immunoelectrophoresis

KW - Middle Aged

KW - Prospective Studies

KW - Time Factors

U2 - 10.3109/00365528309182095

DO - 10.3109/00365528309182095

M3 - Journal article

C2 - 6669942

VL - 18

SP - 783

EP - 789

JO - Scandinavian Journal of Gastroenterology. Supplement

JF - Scandinavian Journal of Gastroenterology. Supplement

SN - 0085-5928

IS - 6

ER -

ID: 218748754