Safety and clinical effect of subcutaneous human interleukin-21 in patients with metastatic melanoma or renal cell carcinoma: a phase I trial

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Safety and clinical effect of subcutaneous human interleukin-21 in patients with metastatic melanoma or renal cell carcinoma: a phase I trial. / Schmidt, Henrik; Brown, Janet; Mouritzen, Ulrik; Selby, Peter; Fode, Kirsten; Svane, Inge Marie; Cook, Graham P; Mollerup, David Hal; Geertsen, Poul F.

In: Clinical Cancer Research, Vol. 16, No. 21, 01.11.2010, p. 5312-9.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Schmidt, H, Brown, J, Mouritzen, U, Selby, P, Fode, K, Svane, IM, Cook, GP, Mollerup, DH & Geertsen, PF 2010, 'Safety and clinical effect of subcutaneous human interleukin-21 in patients with metastatic melanoma or renal cell carcinoma: a phase I trial', Clinical Cancer Research, vol. 16, no. 21, pp. 5312-9. https://doi.org/10.1158/1078-0432.CCR-10-1809

APA

Schmidt, H., Brown, J., Mouritzen, U., Selby, P., Fode, K., Svane, I. M., Cook, G. P., Mollerup, D. H., & Geertsen, P. F. (2010). Safety and clinical effect of subcutaneous human interleukin-21 in patients with metastatic melanoma or renal cell carcinoma: a phase I trial. Clinical Cancer Research, 16(21), 5312-9. https://doi.org/10.1158/1078-0432.CCR-10-1809

Vancouver

Schmidt H, Brown J, Mouritzen U, Selby P, Fode K, Svane IM et al. Safety and clinical effect of subcutaneous human interleukin-21 in patients with metastatic melanoma or renal cell carcinoma: a phase I trial. Clinical Cancer Research. 2010 Nov 1;16(21):5312-9. https://doi.org/10.1158/1078-0432.CCR-10-1809

Author

Schmidt, Henrik ; Brown, Janet ; Mouritzen, Ulrik ; Selby, Peter ; Fode, Kirsten ; Svane, Inge Marie ; Cook, Graham P ; Mollerup, David Hal ; Geertsen, Poul F. / Safety and clinical effect of subcutaneous human interleukin-21 in patients with metastatic melanoma or renal cell carcinoma: a phase I trial. In: Clinical Cancer Research. 2010 ; Vol. 16, No. 21. pp. 5312-9.

Bibtex

@article{4210c3503e20446587dd14619d4b5e3d,
title = "Safety and clinical effect of subcutaneous human interleukin-21 in patients with metastatic melanoma or renal cell carcinoma: a phase I trial",
abstract = "This phase I study in patients with metastatic melanoma (MM) and renal cell carcinoma (RCC) evaluated the safety and maximum tolerated dose (MTD), pharmacokinetics, pharmacodynamics, and preliminary antitumor activity of s.c. treatment of human recombinant interleukin 21 (IL-21).",
author = "Henrik Schmidt and Janet Brown and Ulrik Mouritzen and Peter Selby and Kirsten Fode and Svane, {Inge Marie} and Cook, {Graham P} and Mollerup, {David Hal} and Geertsen, {Poul F}",
note = "{\textcopyright}2010 AACR.",
year = "2010",
month = nov,
day = "1",
doi = "http://dx.doi.org/10.1158/1078-0432.CCR-10-1809",
language = "English",
volume = "16",
pages = "5312--9",
journal = "Clinical Cancer Research",
issn = "1078-0432",
publisher = "American Association for Cancer Research (A A C R)",
number = "21",

}

RIS

TY - JOUR

T1 - Safety and clinical effect of subcutaneous human interleukin-21 in patients with metastatic melanoma or renal cell carcinoma: a phase I trial

AU - Schmidt, Henrik

AU - Brown, Janet

AU - Mouritzen, Ulrik

AU - Selby, Peter

AU - Fode, Kirsten

AU - Svane, Inge Marie

AU - Cook, Graham P

AU - Mollerup, David Hal

AU - Geertsen, Poul F

N1 - ©2010 AACR.

PY - 2010/11/1

Y1 - 2010/11/1

N2 - This phase I study in patients with metastatic melanoma (MM) and renal cell carcinoma (RCC) evaluated the safety and maximum tolerated dose (MTD), pharmacokinetics, pharmacodynamics, and preliminary antitumor activity of s.c. treatment of human recombinant interleukin 21 (IL-21).

AB - This phase I study in patients with metastatic melanoma (MM) and renal cell carcinoma (RCC) evaluated the safety and maximum tolerated dose (MTD), pharmacokinetics, pharmacodynamics, and preliminary antitumor activity of s.c. treatment of human recombinant interleukin 21 (IL-21).

U2 - http://dx.doi.org/10.1158/1078-0432.CCR-10-1809

DO - http://dx.doi.org/10.1158/1078-0432.CCR-10-1809

M3 - Journal article

VL - 16

SP - 5312

EP - 5319

JO - Clinical Cancer Research

JF - Clinical Cancer Research

SN - 1078-0432

IS - 21

ER -

ID: 34133708