Rho GTPase function in development: How in vivo models change our view

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Rho GTPase function in development : How in vivo models change our view. / Pedersen, Esben; Brakebusch, Cord.

In: Experimental Cell Research, Vol. 318, No. 14, 29.05.2012, p. 1779-87.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Pedersen, E & Brakebusch, C 2012, 'Rho GTPase function in development: How in vivo models change our view', Experimental Cell Research, vol. 318, no. 14, pp. 1779-87. https://doi.org/10.1016/j.yexcr.2012.05.004

APA

Pedersen, E., & Brakebusch, C. (2012). Rho GTPase function in development: How in vivo models change our view. Experimental Cell Research, 318(14), 1779-87. https://doi.org/10.1016/j.yexcr.2012.05.004

Vancouver

Pedersen E, Brakebusch C. Rho GTPase function in development: How in vivo models change our view. Experimental Cell Research. 2012 May 29;318(14):1779-87. https://doi.org/10.1016/j.yexcr.2012.05.004

Author

Pedersen, Esben ; Brakebusch, Cord. / Rho GTPase function in development : How in vivo models change our view. In: Experimental Cell Research. 2012 ; Vol. 318, No. 14. pp. 1779-87.

Bibtex

@article{408aa93373df437dafcec53afa9dd60a,
title = "Rho GTPase function in development: How in vivo models change our view",
abstract = "Rho GTPase functions have been carefully investigated for many years using cell biological models. In recent years, mouse models with targeted mutations in Rho GTPase genes enabled the study of Rho GTPase function in vivo, partially confirming and partially contradicting expectations based on earlier in vitro experiments. This review sums up recent findings on the role of Rho GTPases in development, underlining the importance of in vivo research for our understanding of Rho GTPases in living organisms, and describing challenges for the future.",
author = "Esben Pedersen and Cord Brakebusch",
note = "Copyright {\textcopyright} 2012 Elsevier Inc. All rights reserved.",
year = "2012",
month = may,
day = "29",
doi = "10.1016/j.yexcr.2012.05.004",
language = "English",
volume = "318",
pages = "1779--87",
journal = "Experimental Cell Research",
issn = "0014-4827",
publisher = "Academic Press",
number = "14",

}

RIS

TY - JOUR

T1 - Rho GTPase function in development

T2 - How in vivo models change our view

AU - Pedersen, Esben

AU - Brakebusch, Cord

N1 - Copyright © 2012 Elsevier Inc. All rights reserved.

PY - 2012/5/29

Y1 - 2012/5/29

N2 - Rho GTPase functions have been carefully investigated for many years using cell biological models. In recent years, mouse models with targeted mutations in Rho GTPase genes enabled the study of Rho GTPase function in vivo, partially confirming and partially contradicting expectations based on earlier in vitro experiments. This review sums up recent findings on the role of Rho GTPases in development, underlining the importance of in vivo research for our understanding of Rho GTPases in living organisms, and describing challenges for the future.

AB - Rho GTPase functions have been carefully investigated for many years using cell biological models. In recent years, mouse models with targeted mutations in Rho GTPase genes enabled the study of Rho GTPase function in vivo, partially confirming and partially contradicting expectations based on earlier in vitro experiments. This review sums up recent findings on the role of Rho GTPases in development, underlining the importance of in vivo research for our understanding of Rho GTPases in living organisms, and describing challenges for the future.

U2 - 10.1016/j.yexcr.2012.05.004

DO - 10.1016/j.yexcr.2012.05.004

M3 - Journal article

C2 - 22659168

VL - 318

SP - 1779

EP - 1787

JO - Experimental Cell Research

JF - Experimental Cell Research

SN - 0014-4827

IS - 14

ER -

ID: 40299588