Reproducibility of [123I]PE2I binding to dopamine transporters with SPECT
Research output: Contribution to journal › Journal article › Research
The iodinated cocaine derivative [(123)I]PE2I is a new selective ligand for in vivo studies of the dopamine transporter (DAT) with SPECT. Recently, a bolus/infusion (B/I) protocol for [(123)I]PE2I measurements of DAT density was established [Pinborg LH et al. J Nucl Med 2005;46:1119-271]. The aims of this study were, firstly, to evaluate the test-retest variability using the B/I protocol and, secondly, to evaluate the B/I approach in a new group of healthy subjects using two outcome parameters, BP(1) (C(ROI)/C(plasma)) and BP(2) (C(ROI)/C(REF)).
Original language | English |
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Journal | European Journal of Nuclear Medicine and Molecular Imaging |
Volume | 34 |
Issue number | 1 |
Pages (from-to) | 101-9 |
Number of pages | 9 |
ISSN | 1619-7070 |
DOIs | |
Publication status | Published - 1 Jan 2007 |
ID: 34094258