Reliability of clinical ICD-10 schizophrenia diagnoses
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Concern has been expressed as to the reliability of clinical ICD-10 diagnosis of schizophrenia. This study was designed to assess the diagnostic reliability of the clinical ICD-10 diagnosis of schizophrenia in a random sample of Danish in- and outpatients with a history of psychosis. A sample of 100 subjects was assessed using the operational criteria OPCRIT checklist for psychotic and affective illness. The most recent principal and clinical ICD-10 diagnosis was compared with diagnoses generated by the OPCRIT instrument. Data documented very high sensitivity (93%) and positive predictive value (87%) of ICD-10 schizophrenia and an overall good agreement between clinical and OPCRIT-derived diagnoses (kappa=0.60). An even higher positive predictive value was obtained when diagnoses were amalgamated into a diagnostic entity of schizophrenia-spectrum disorders (98%). Near perfect agreement was seen between OPCRIT-derived ICD-10 and DSM-IV diagnoses (kappa=0.87). Thus, this study demonstrates high reliability of the clinical diagnosis of schizophrenia and even more so of the diagnosis of schizophrenia-spectrum disorder.
Original language | English |
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Journal | Nordic Journal of Psychiatry |
Volume | 59 |
Issue number | 3 |
Pages (from-to) | 209-12 |
Number of pages | 4 |
ISSN | 0803-9488 |
DOIs | |
Publication status | Published - 2005 |
- Adult, Denmark, Female, Humans, International Classification of Diseases, Male, Predictive Value of Tests, Psychiatric Status Rating Scales, Psychotic Disorders, Reproducibility of Results, Schizophrenia, Schizophrenic Psychology, Sensitivity and Specificity, Comparative Study, Journal Article, Research Support, Non-U.S. Gov't
Research areas
ID: 187623978