(-)-(R)-5,5-dimethylmorpholinyl-2-acetic acid ethyl ester hydrochloride, C10H20NO3+.Cl-

Research output: Contribution to journalJournal articleResearchpeer-review

One of the enantiomers of 5,5-dimethylmorpholinyl-2-acetic acid is observed to be a GABAB receptor antagonist. The absolute configuration of the inactive enantiomer is found to be the R configuration. The morpholine ring adopts a chair conformation with the acetic acid moiety in an equatorial position. In the crystal packing, hydrogen bonds are observed between the ammonium group and the chloride ions.

Original languageEnglish
JournalActa Crystallographica Section C: Crystal Structure Communications
Issue number8
Pages (from-to)1088-1091
Number of pages4
Publication statusPublished - 15 Aug 1997

ID: 382748111