Psychopharmacology in children and adolescents: unmet needs and opportunities

Research output: Contribution to journalReviewResearchpeer-review

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Psychopharmacology in children and adolescents : unmet needs and opportunities. / Cortese, Samuele; Purper-Ouakil, Diane; Apter, Alan; Arango, Celso; Baeza, Inmaculada; Banaschewski, Tobias; Buitelaar, Jan; Castro-Fornieles, Josefina; Coghill, David; Cohen, David; Correll, Christoph U.; Grünblatt, Edna; Hoekstra, Pieter J.; James, Anthony; Jeppesen, Pia; Nagy, Péter; Pagsberg, Anne Katrine; Parellada, Mara; Persico, Antonio M.; Roessner, Veit; Santosh, Paramala; Simonoff, Emily; Stevanovic, Dejan; Stringaris, Argyris; Vitiello, Benedetto; Walitza, Susanne; Weizman, Abraham; Wong, Ian C.K.; Zalsman, Gil; Zuddas, Alessandro; Carucci, Sara; Butlen-Ducuing, Florence; Tome, Maria; Bea, Myriam; Getin, Christine; Hovén, Nina; Konradsson-Geuken, Asa; Lamirell, Daphne; Olisa, Nigel; Nafria Escalera, Begonya; Moreno, Carmen.

In: The Lancet Psychiatry, Vol. 11, No. 2, 2024, p. 143-154.

Research output: Contribution to journalReviewResearchpeer-review

Harvard

Cortese, S, Purper-Ouakil, D, Apter, A, Arango, C, Baeza, I, Banaschewski, T, Buitelaar, J, Castro-Fornieles, J, Coghill, D, Cohen, D, Correll, CU, Grünblatt, E, Hoekstra, PJ, James, A, Jeppesen, P, Nagy, P, Pagsberg, AK, Parellada, M, Persico, AM, Roessner, V, Santosh, P, Simonoff, E, Stevanovic, D, Stringaris, A, Vitiello, B, Walitza, S, Weizman, A, Wong, ICK, Zalsman, G, Zuddas, A, Carucci, S, Butlen-Ducuing, F, Tome, M, Bea, M, Getin, C, Hovén, N, Konradsson-Geuken, A, Lamirell, D, Olisa, N, Nafria Escalera, B & Moreno, C 2024, 'Psychopharmacology in children and adolescents: unmet needs and opportunities', The Lancet Psychiatry, vol. 11, no. 2, pp. 143-154. https://doi.org/10.1016/S2215-0366(23)00345-0

APA

Cortese, S., Purper-Ouakil, D., Apter, A., Arango, C., Baeza, I., Banaschewski, T., Buitelaar, J., Castro-Fornieles, J., Coghill, D., Cohen, D., Correll, C. U., Grünblatt, E., Hoekstra, P. J., James, A., Jeppesen, P., Nagy, P., Pagsberg, A. K., Parellada, M., Persico, A. M., ... Moreno, C. (2024). Psychopharmacology in children and adolescents: unmet needs and opportunities. The Lancet Psychiatry, 11(2), 143-154. https://doi.org/10.1016/S2215-0366(23)00345-0

Vancouver

Cortese S, Purper-Ouakil D, Apter A, Arango C, Baeza I, Banaschewski T et al. Psychopharmacology in children and adolescents: unmet needs and opportunities. The Lancet Psychiatry. 2024;11(2):143-154. https://doi.org/10.1016/S2215-0366(23)00345-0

Author

Cortese, Samuele ; Purper-Ouakil, Diane ; Apter, Alan ; Arango, Celso ; Baeza, Inmaculada ; Banaschewski, Tobias ; Buitelaar, Jan ; Castro-Fornieles, Josefina ; Coghill, David ; Cohen, David ; Correll, Christoph U. ; Grünblatt, Edna ; Hoekstra, Pieter J. ; James, Anthony ; Jeppesen, Pia ; Nagy, Péter ; Pagsberg, Anne Katrine ; Parellada, Mara ; Persico, Antonio M. ; Roessner, Veit ; Santosh, Paramala ; Simonoff, Emily ; Stevanovic, Dejan ; Stringaris, Argyris ; Vitiello, Benedetto ; Walitza, Susanne ; Weizman, Abraham ; Wong, Ian C.K. ; Zalsman, Gil ; Zuddas, Alessandro ; Carucci, Sara ; Butlen-Ducuing, Florence ; Tome, Maria ; Bea, Myriam ; Getin, Christine ; Hovén, Nina ; Konradsson-Geuken, Asa ; Lamirell, Daphne ; Olisa, Nigel ; Nafria Escalera, Begonya ; Moreno, Carmen. / Psychopharmacology in children and adolescents : unmet needs and opportunities. In: The Lancet Psychiatry. 2024 ; Vol. 11, No. 2. pp. 143-154.

Bibtex

@article{18a4a400b5744c4385fef8e8daab4732,
title = "Psychopharmacology in children and adolescents: unmet needs and opportunities",
abstract = "Psychopharmacological treatment is an important component of the multimodal intervention approach to treating mental health conditions in children and adolescents. Currently, there are many unmet needs but also opportunities, alongside possible risks to consider, regarding the pharmacological treatment of mental health conditions in children and adolescents. In this Position Paper, we highlight and address these unmet needs and opportunities, including the perspectives of clinicians and researchers from the European College of Neuropsychopharmacology–Child and Adolescent Network, alongside those of experts by lived experience from national and international associations, via a survey involving 644 participants from 13 countries, and of regulators, through representation from the European Medicines Agency. We present and discuss the evidence base for medications currently used for mental disorders in children and adolescents, medications in the pipeline, opportunities in the development of novel medications, crucial priorities for the conduct of future clinical studies, challenges and opportunities in terms of the regulatory and legislative framework, and innovations in the way research is conducted, reported, and promoted.",
author = "Samuele Cortese and Diane Purper-Ouakil and Alan Apter and Celso Arango and Inmaculada Baeza and Tobias Banaschewski and Jan Buitelaar and Josefina Castro-Fornieles and David Coghill and David Cohen and Correll, {Christoph U.} and Edna Gr{\"u}nblatt and Hoekstra, {Pieter J.} and Anthony James and Pia Jeppesen and P{\'e}ter Nagy and Pagsberg, {Anne Katrine} and Mara Parellada and Persico, {Antonio M.} and Veit Roessner and Paramala Santosh and Emily Simonoff and Dejan Stevanovic and Argyris Stringaris and Benedetto Vitiello and Susanne Walitza and Abraham Weizman and Wong, {Ian C.K.} and Gil Zalsman and Alessandro Zuddas and Sara Carucci and Florence Butlen-Ducuing and Maria Tome and Myriam Bea and Christine Getin and Nina Hov{\'e}n and Asa Konradsson-Geuken and Daphne Lamirell and Nigel Olisa and {Nafria Escalera}, Begonya and Carmen Moreno",
note = "Publisher Copyright: {\textcopyright} 2024 Elsevier Ltd",
year = "2024",
doi = "10.1016/S2215-0366(23)00345-0",
language = "English",
volume = "11",
pages = "143--154",
journal = "The Lancet Psychiatry",
issn = "2215-0366",
publisher = "TheLancet Publishing Group",
number = "2",

}

RIS

TY - JOUR

T1 - Psychopharmacology in children and adolescents

T2 - unmet needs and opportunities

AU - Cortese, Samuele

AU - Purper-Ouakil, Diane

AU - Apter, Alan

AU - Arango, Celso

AU - Baeza, Inmaculada

AU - Banaschewski, Tobias

AU - Buitelaar, Jan

AU - Castro-Fornieles, Josefina

AU - Coghill, David

AU - Cohen, David

AU - Correll, Christoph U.

AU - Grünblatt, Edna

AU - Hoekstra, Pieter J.

AU - James, Anthony

AU - Jeppesen, Pia

AU - Nagy, Péter

AU - Pagsberg, Anne Katrine

AU - Parellada, Mara

AU - Persico, Antonio M.

AU - Roessner, Veit

AU - Santosh, Paramala

AU - Simonoff, Emily

AU - Stevanovic, Dejan

AU - Stringaris, Argyris

AU - Vitiello, Benedetto

AU - Walitza, Susanne

AU - Weizman, Abraham

AU - Wong, Ian C.K.

AU - Zalsman, Gil

AU - Zuddas, Alessandro

AU - Carucci, Sara

AU - Butlen-Ducuing, Florence

AU - Tome, Maria

AU - Bea, Myriam

AU - Getin, Christine

AU - Hovén, Nina

AU - Konradsson-Geuken, Asa

AU - Lamirell, Daphne

AU - Olisa, Nigel

AU - Nafria Escalera, Begonya

AU - Moreno, Carmen

N1 - Publisher Copyright: © 2024 Elsevier Ltd

PY - 2024

Y1 - 2024

N2 - Psychopharmacological treatment is an important component of the multimodal intervention approach to treating mental health conditions in children and adolescents. Currently, there are many unmet needs but also opportunities, alongside possible risks to consider, regarding the pharmacological treatment of mental health conditions in children and adolescents. In this Position Paper, we highlight and address these unmet needs and opportunities, including the perspectives of clinicians and researchers from the European College of Neuropsychopharmacology–Child and Adolescent Network, alongside those of experts by lived experience from national and international associations, via a survey involving 644 participants from 13 countries, and of regulators, through representation from the European Medicines Agency. We present and discuss the evidence base for medications currently used for mental disorders in children and adolescents, medications in the pipeline, opportunities in the development of novel medications, crucial priorities for the conduct of future clinical studies, challenges and opportunities in terms of the regulatory and legislative framework, and innovations in the way research is conducted, reported, and promoted.

AB - Psychopharmacological treatment is an important component of the multimodal intervention approach to treating mental health conditions in children and adolescents. Currently, there are many unmet needs but also opportunities, alongside possible risks to consider, regarding the pharmacological treatment of mental health conditions in children and adolescents. In this Position Paper, we highlight and address these unmet needs and opportunities, including the perspectives of clinicians and researchers from the European College of Neuropsychopharmacology–Child and Adolescent Network, alongside those of experts by lived experience from national and international associations, via a survey involving 644 participants from 13 countries, and of regulators, through representation from the European Medicines Agency. We present and discuss the evidence base for medications currently used for mental disorders in children and adolescents, medications in the pipeline, opportunities in the development of novel medications, crucial priorities for the conduct of future clinical studies, challenges and opportunities in terms of the regulatory and legislative framework, and innovations in the way research is conducted, reported, and promoted.

U2 - 10.1016/S2215-0366(23)00345-0

DO - 10.1016/S2215-0366(23)00345-0

M3 - Review

C2 - 38071998

AN - SCOPUS:85181653674

VL - 11

SP - 143

EP - 154

JO - The Lancet Psychiatry

JF - The Lancet Psychiatry

SN - 2215-0366

IS - 2

ER -

ID: 381069337