TY - JOUR

T1 - Predictors of Postoperative Atrial Fibrillation After Abdominal Surgery and Insights from Other Surgery Types

AU - Madsen, Christoffer Valdorff

AU - Jorgensen, Lars Nannestad

AU - Leerhoy, Bonna

AU - Gogenur, Ismail

AU - Ekeloef, Sarah

AU - Sajadieh, Ahmad

AU - Dominguez, Helena

PY - 2020

Y1 - 2020

N2 - Postoperative atrial fibrillation (POAF) in relation to abdominal surgery can cause clinical deterioration, prolonged hospitalization, admittance to intensive care units, stroke and increased mortality. The current review focus on patients developing POAF in relation to abdominal surgery and aims to present the current knowledge on predictors of this condition. Furthermore, predictors identified in other surgical populations that may be transferable and guide future research within the field of abdominal surgery will be presented. A systematic literature search of patients undergoing abdominal surgery and developing POAF was performed on PubMed and Embase. All types of study interventions, comparators and designs were included. All studies included reported POAF as primary or secondary outcome. All peer-reviewed English full-text manuscripts regardless of publication date were included. We included five studies out of the 149 unique records identified. Age, congestive heart failure, hypertension, vascular disease and surgical approach are risk factors associated with the development of POAF. Furthermore, inflammation biomarkers, dobutamine stress echocardiography and cardiac single-photon emission computed tomography can predict POAF. Insights from other surgical cohorts reveal that other biomarkers (ie, brain natriuretic peptide (BNP) and N-terminal pro-BNP), electrocardiography and echocardiography can be used to predict POAF and may be applied in future research projects within the field of abdominal surgery. In conclusion, very scarce evidence is currently available in predicting POAF after abdominal surgery. However, predicting POAF seems possible and feasible, why the authors encourage readers to initiate new research to close the current knowledge gap and improve clinical management.

AB - Postoperative atrial fibrillation (POAF) in relation to abdominal surgery can cause clinical deterioration, prolonged hospitalization, admittance to intensive care units, stroke and increased mortality. The current review focus on patients developing POAF in relation to abdominal surgery and aims to present the current knowledge on predictors of this condition. Furthermore, predictors identified in other surgical populations that may be transferable and guide future research within the field of abdominal surgery will be presented. A systematic literature search of patients undergoing abdominal surgery and developing POAF was performed on PubMed and Embase. All types of study interventions, comparators and designs were included. All studies included reported POAF as primary or secondary outcome. All peer-reviewed English full-text manuscripts regardless of publication date were included. We included five studies out of the 149 unique records identified. Age, congestive heart failure, hypertension, vascular disease and surgical approach are risk factors associated with the development of POAF. Furthermore, inflammation biomarkers, dobutamine stress echocardiography and cardiac single-photon emission computed tomography can predict POAF. Insights from other surgical cohorts reveal that other biomarkers (ie, brain natriuretic peptide (BNP) and N-terminal pro-BNP), electrocardiography and echocardiography can be used to predict POAF and may be applied in future research projects within the field of abdominal surgery. In conclusion, very scarce evidence is currently available in predicting POAF after abdominal surgery. However, predicting POAF seems possible and feasible, why the authors encourage readers to initiate new research to close the current knowledge gap and improve clinical management.

KW - postoperative atrial fibrillation

KW - surgery

KW - biomarkers

KW - electrocardiogram

KW - echocardiography

KW - complications

KW - BRAIN NATRIURETIC PEPTIDE

KW - CARDIAC-SURGERY

KW - NONCARDIAC SURGERY

KW - DIASTOLIC DYSFUNCTION

KW - BYPASS-SURGERY

KW - P-WAVE

KW - ONSET

KW - RISK

KW - MANAGEMENT

KW - GUIDELINES

U2 - 10.2147/RRCC.S197407

DO - 10.2147/RRCC.S197407

M3 - Review

VL - 2020

SP - 31

EP - 38

JO - Research Reports in Clinical Cardiology

JF - Research Reports in Clinical Cardiology

SN - 1179-8475

IS - 11

ER -