Patients with Unstable Atherosclerosis Have More Echolucent Carotid Plaques Compared with Stable Atherosclerotic Patients: A 3-D Ultrasound Study

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Patients with Unstable Atherosclerosis Have More Echolucent Carotid Plaques Compared with Stable Atherosclerotic Patients : A 3-D Ultrasound Study. / Urbak, Lærke; Sandholt, Benjamin V.; Graebe, Martin; Bang, Lia E.; Bundgaard, Henning; Sillesen, Henrik.

In: Ultrasound in Medicine and Biology, Vol. 46, No. 9, 2020, p. 2164-2172.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Urbak, L, Sandholt, BV, Graebe, M, Bang, LE, Bundgaard, H & Sillesen, H 2020, 'Patients with Unstable Atherosclerosis Have More Echolucent Carotid Plaques Compared with Stable Atherosclerotic Patients: A 3-D Ultrasound Study', Ultrasound in Medicine and Biology, vol. 46, no. 9, pp. 2164-2172. https://doi.org/10.1016/j.ultrasmedbio.2020.04.002

APA

Urbak, L., Sandholt, B. V., Graebe, M., Bang, L. E., Bundgaard, H., & Sillesen, H. (2020). Patients with Unstable Atherosclerosis Have More Echolucent Carotid Plaques Compared with Stable Atherosclerotic Patients: A 3-D Ultrasound Study. Ultrasound in Medicine and Biology, 46(9), 2164-2172. https://doi.org/10.1016/j.ultrasmedbio.2020.04.002

Vancouver

Urbak L, Sandholt BV, Graebe M, Bang LE, Bundgaard H, Sillesen H. Patients with Unstable Atherosclerosis Have More Echolucent Carotid Plaques Compared with Stable Atherosclerotic Patients: A 3-D Ultrasound Study. Ultrasound in Medicine and Biology. 2020;46(9):2164-2172. https://doi.org/10.1016/j.ultrasmedbio.2020.04.002

Author

Urbak, Lærke ; Sandholt, Benjamin V. ; Graebe, Martin ; Bang, Lia E. ; Bundgaard, Henning ; Sillesen, Henrik. / Patients with Unstable Atherosclerosis Have More Echolucent Carotid Plaques Compared with Stable Atherosclerotic Patients : A 3-D Ultrasound Study. In: Ultrasound in Medicine and Biology. 2020 ; Vol. 46, No. 9. pp. 2164-2172.

Bibtex

@article{f2a5aab7f9ce4043bd047ca673608cdf,
title = "Patients with Unstable Atherosclerosis Have More Echolucent Carotid Plaques Compared with Stable Atherosclerotic Patients: A 3-D Ultrasound Study",
abstract = "Using a novel 3-D ultrasound system, we aimed to determine differences in carotid plaque size and echogenicity in two atherosclerotic groups. Seventy patients admitted with acute myocardial infarction (aMI) and 69 patients known with chronic peripheral arterial disease (cPAD) were included. The cPAD group had larger plaque volumes (median: 70.24 mm3, interquartile range [40.12–135.61] vs. 55.41 mm3 [4.24–84.31], p = 0.004), thicker plaques (2.45 mm [1.85–3.25] vs. 1.99 mm [1.55 – 2.64], p = 0.005) and higher gray-scale medians (GSMs) (mean: 71.75, standard deviation: 21.55 vs. 60.99 [24.09], p = 0.006) than the aMI group. After adjustment for traditional risk factors, the difference persisted for thickness and volume. The difference in GSM persisted after adjustment for volume only. Patients with stable atherosclerotic disease had larger and brighter carotid plaques compared with unstable atherosclerotic patients. 3-D ultrasound may prove useful in identifying thromboembolic risk.",
keywords = "Atherosclerotic disease, Atherosclerotic plaque, Carotid artery plaque, Gray-scale median, Three-dimensional ultrasound",
author = "L{\ae}rke Urbak and Sandholt, {Benjamin V.} and Martin Graebe and Bang, {Lia E.} and Henning Bundgaard and Henrik Sillesen",
year = "2020",
doi = "10.1016/j.ultrasmedbio.2020.04.002",
language = "English",
volume = "46",
pages = "2164--2172",
journal = "Ultrasound in Medicine & Biology",
issn = "0301-5629",
publisher = "Elsevier",
number = "9",

}

RIS

TY - JOUR

T1 - Patients with Unstable Atherosclerosis Have More Echolucent Carotid Plaques Compared with Stable Atherosclerotic Patients

T2 - A 3-D Ultrasound Study

AU - Urbak, Lærke

AU - Sandholt, Benjamin V.

AU - Graebe, Martin

AU - Bang, Lia E.

AU - Bundgaard, Henning

AU - Sillesen, Henrik

PY - 2020

Y1 - 2020

N2 - Using a novel 3-D ultrasound system, we aimed to determine differences in carotid plaque size and echogenicity in two atherosclerotic groups. Seventy patients admitted with acute myocardial infarction (aMI) and 69 patients known with chronic peripheral arterial disease (cPAD) were included. The cPAD group had larger plaque volumes (median: 70.24 mm3, interquartile range [40.12–135.61] vs. 55.41 mm3 [4.24–84.31], p = 0.004), thicker plaques (2.45 mm [1.85–3.25] vs. 1.99 mm [1.55 – 2.64], p = 0.005) and higher gray-scale medians (GSMs) (mean: 71.75, standard deviation: 21.55 vs. 60.99 [24.09], p = 0.006) than the aMI group. After adjustment for traditional risk factors, the difference persisted for thickness and volume. The difference in GSM persisted after adjustment for volume only. Patients with stable atherosclerotic disease had larger and brighter carotid plaques compared with unstable atherosclerotic patients. 3-D ultrasound may prove useful in identifying thromboembolic risk.

AB - Using a novel 3-D ultrasound system, we aimed to determine differences in carotid plaque size and echogenicity in two atherosclerotic groups. Seventy patients admitted with acute myocardial infarction (aMI) and 69 patients known with chronic peripheral arterial disease (cPAD) were included. The cPAD group had larger plaque volumes (median: 70.24 mm3, interquartile range [40.12–135.61] vs. 55.41 mm3 [4.24–84.31], p = 0.004), thicker plaques (2.45 mm [1.85–3.25] vs. 1.99 mm [1.55 – 2.64], p = 0.005) and higher gray-scale medians (GSMs) (mean: 71.75, standard deviation: 21.55 vs. 60.99 [24.09], p = 0.006) than the aMI group. After adjustment for traditional risk factors, the difference persisted for thickness and volume. The difference in GSM persisted after adjustment for volume only. Patients with stable atherosclerotic disease had larger and brighter carotid plaques compared with unstable atherosclerotic patients. 3-D ultrasound may prove useful in identifying thromboembolic risk.

KW - Atherosclerotic disease

KW - Atherosclerotic plaque

KW - Carotid artery plaque

KW - Gray-scale median

KW - Three-dimensional ultrasound

U2 - 10.1016/j.ultrasmedbio.2020.04.002

DO - 10.1016/j.ultrasmedbio.2020.04.002

M3 - Journal article

C2 - 32522459

AN - SCOPUS:85086046922

VL - 46

SP - 2164

EP - 2172

JO - Ultrasound in Medicine & Biology

JF - Ultrasound in Medicine & Biology

SN - 0301-5629

IS - 9

ER -

ID: 260999691