[New marker in thrombotic thrombocytopenic purpura]

Research output: Contribution to journalJournal articleResearchpeer-review

Thrombotic microangiopathy can be caused by several conditions which are difficult to diagnose from the clinical presentation alone. Deficient enzyme activity of a newly-discovered enzyme, ADAMTS-13, can lead to thrombotic thrombocytopenic purpura (TTP). Lack of ADAMTS-13 activity causes increased concentrations of high molecular weight von Willebrand factor forms and increased platelet aggregation. Measurement of ADAMTS-13 activity is useful for the diagnosis of TTP and may also be relevant as a prognostic test for recurrent TTP
Udgivelsesdato: 2008/8/11
Original languageDanish
JournalUgeskrift for læger
Issue number33
Pages (from-to)2446-2449
Number of pages3
Publication statusPublished - 2008

ID: 14150547