MRI-guided region-of-interest delineation is comparable to manual delineation in dopamine transporter SPECT quantification in patients: a reproducibility study
Research output: Contribution to journal › Journal article › Research › peer-review
A particularly sensitive step in the quantification of SPECT images of the dopamine transporter (DAT) is a correct delineation of the region of interest (ROI). In this study, we primarily compared the reproducibility of the following different approaches for ROI delineation in SPECT images of the DAT: the use of manual delineation (MD) on high-count striatal slides directly on the SPECT image, ROI delineation based on individual MR images (MRD), and oversized striatal ROIs-that is, the striatal volume of interest (SVI), as described previously. We also assessed the ability of the different approaches to identify striatal pathology in patients with parkinsonism.
Original language | English |
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Journal | Journal of Nuclear Medicine Technology |
Volume | 38 |
Issue number | 2 |
Pages (from-to) | 61-8 |
Number of pages | 8 |
ISSN | 0091-4916 |
DOIs | |
Publication status | Published - 1 Jun 2010 |
ID: 34094241