Long-term outcomes for children conceived by assisted reproductive technology

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Long-term outcomes for children conceived by assisted reproductive technology. / Pinborg, Anja; Wennerholm, Ulla Britt; Bergh, Christina.

In: Fertility and Sterility, Vol. 120, No. 3, Part 1, 2023, p. 449-456.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Pinborg, A, Wennerholm, UB & Bergh, C 2023, 'Long-term outcomes for children conceived by assisted reproductive technology', Fertility and Sterility, vol. 120, no. 3, Part 1, pp. 449-456. https://doi.org/10.1016/j.fertnstert.2023.04.022

APA

Pinborg, A., Wennerholm, U. B., & Bergh, C. (2023). Long-term outcomes for children conceived by assisted reproductive technology. Fertility and Sterility, 120(3, Part 1), 449-456. https://doi.org/10.1016/j.fertnstert.2023.04.022

Vancouver

Pinborg A, Wennerholm UB, Bergh C. Long-term outcomes for children conceived by assisted reproductive technology. Fertility and Sterility. 2023;120(3, Part 1):449-456. https://doi.org/10.1016/j.fertnstert.2023.04.022

Author

Pinborg, Anja ; Wennerholm, Ulla Britt ; Bergh, Christina. / Long-term outcomes for children conceived by assisted reproductive technology. In: Fertility and Sterility. 2023 ; Vol. 120, No. 3, Part 1. pp. 449-456.

Bibtex

@article{3af3e3d730c5482997567df6426aabe2,

title = "Long-term outcomes for children conceived by assisted reproductive technology",

abstract = "Worldwide, more than 10 million children have been born after assisted reproduction technology (ART), comprising up to 7.9% of children born in Europe and up to 5.1 % of children born in the US in 2018. The short-term outcome for children born after ART is well-known from numerous publications, with higher rates of preterm birth and low birth weight in children born after fresh embryo transfer and higher rates of large for gestational age and high birth weight in children born after frozen embryo transfer compared with children born after spontaneous conception. Higher rates of birth defects in children born after ART have also been shown consistently over time. Studies on long-term health outcomes after ART are scarcer but suggest an increased risk of altered blood pressure and cardiovascular function in children born after ART. In this review, we summarize long-term health outcomes in children born after ART and discuss whether the increased health risks are associated with intrinsic maternal or paternal factors related to subfertility or ART treatments per se. Finally, we speculate where the future will bring us regarding ART treatment strategies and the safety of the mother and child.",

keywords = "ART, cancer, cardiometabolic disease, frozen embryo transfer, long-term health",

author = "Anja Pinborg and Wennerholm, {Ulla Britt} and Christina Bergh",

note = "Publisher Copyright: {\textcopyright} 2023 The Authors",

year = "2023",

doi = "10.1016/j.fertnstert.2023.04.022",

language = "English",

volume = "120",

pages = "449--456",

journal = "Sexuality, Reproduction and Menopause",

issn = "1546-2501",

publisher = "Elsevier",

number = "3, Part 1",

}

RIS

TY - JOUR

T1 - Long-term outcomes for children conceived by assisted reproductive technology

AU - Pinborg, Anja

AU - Wennerholm, Ulla Britt

AU - Bergh, Christina

PY - 2023

Y1 - 2023

N2 - Worldwide, more than 10 million children have been born after assisted reproduction technology (ART), comprising up to 7.9% of children born in Europe and up to 5.1 % of children born in the US in 2018. The short-term outcome for children born after ART is well-known from numerous publications, with higher rates of preterm birth and low birth weight in children born after fresh embryo transfer and higher rates of large for gestational age and high birth weight in children born after frozen embryo transfer compared with children born after spontaneous conception. Higher rates of birth defects in children born after ART have also been shown consistently over time. Studies on long-term health outcomes after ART are scarcer but suggest an increased risk of altered blood pressure and cardiovascular function in children born after ART. In this review, we summarize long-term health outcomes in children born after ART and discuss whether the increased health risks are associated with intrinsic maternal or paternal factors related to subfertility or ART treatments per se. Finally, we speculate where the future will bring us regarding ART treatment strategies and the safety of the mother and child.

AB - Worldwide, more than 10 million children have been born after assisted reproduction technology (ART), comprising up to 7.9% of children born in Europe and up to 5.1 % of children born in the US in 2018. The short-term outcome for children born after ART is well-known from numerous publications, with higher rates of preterm birth and low birth weight in children born after fresh embryo transfer and higher rates of large for gestational age and high birth weight in children born after frozen embryo transfer compared with children born after spontaneous conception. Higher rates of birth defects in children born after ART have also been shown consistently over time. Studies on long-term health outcomes after ART are scarcer but suggest an increased risk of altered blood pressure and cardiovascular function in children born after ART. In this review, we summarize long-term health outcomes in children born after ART and discuss whether the increased health risks are associated with intrinsic maternal or paternal factors related to subfertility or ART treatments per se. Finally, we speculate where the future will bring us regarding ART treatment strategies and the safety of the mother and child.

KW - ART

KW - cancer

KW - cardiometabolic disease

KW - frozen embryo transfer

KW - long-term health

U2 - 10.1016/j.fertnstert.2023.04.022

DO - 10.1016/j.fertnstert.2023.04.022

M3 - Journal article

C2 - 37086833

AN - SCOPUS:85159233348

VL - 120

SP - 449

EP - 456

JO - Sexuality, Reproduction and Menopause

JF - Sexuality, Reproduction and Menopause

SN - 1546-2501

IS - 3, Part 1

ER -

ID: 360030809