Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism
Research output: Contribution to journal › Journal article › Research › peer-review
Large-scale sequencing of patients with autism allows identification of over 100 putative ASD-associated genes, the majority of which are neuronally expressed, and investigation of distinct genetic influences on ASD compared with other neurodevelopmental disorders.
| Original language | English |
|---|---|
| Journal | Cell |
| Volume | 180 |
| Issue number | 3 |
| Pages (from-to) | 568-584.e23 |
| ISSN | 0092-8674 |
| DOIs | |
| Publication status | Published - 2020 |
- autism spectrum disorder, cell type, cytoskeleton, excitatory neurons, excitatory-inhibitory balance, exome sequencing, genetics, inhibitory neurons, liability, neurodevelopment
Research areas
Links
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250485/pdf/nihms-1569306.pdf
Accepted author manuscript
ID: 260243575