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Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism. / Satterstrom, F. Kyle; Kosmicki, Jack A.; Wang, Jiebiao; Breen, Michael S.; De Rubeis, Silvia; An, Joon Yong; Peng, Minshi; Collins, Ryan; Grove, Jakob; Klei, Lambertus; Stevens, Christine; Reichert, Jennifer; Mulhern, Maureen S.; Artomov, Mykyta; Gerges, Sherif; Sheppard, Brooke; Xu, Xinyi; Bhaduri, Aparna; Norman, Utku; Brand, Harrison; Schwartz, Grace; Nguyen, Rachel; Guerrero, Elizabeth E.; Dias, Caroline; Aleksic, Branko; Anney, Richard; Barbosa, Mafalda; Bishop, Somer; Brusco, Alfredo; Bybjerg-Grauholm, Jonas; Carracedo, Angel; Chan, Marcus C.Y.; Chiocchetti, Andreas G.; Chung, Brian H.Y.; Coon, Hilary; Cuccaro, Michael L.; Curró, Aurora; Dalla Bernardina, Bernardo; Doan, Ryan; Domenici, Enrico; Dong, Shan; Fallerini, Chiara; Fernández-Prieto, Montserrat; Ferrero, Giovanni Battista; Nordentoft, Merete; Werge, Thomas; Appadurai, Vivek; Bækvad-Hansen, Marie; Hansen, Christine S.; Pedersen, Carsten Bøcker; iPSYCH-Broad Consortium; Autism Sequencing Consortium.
In:
Cell, Vol. 180, No. 3, 2020, p. 568-584.e23.
Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
Satterstrom, FK, Kosmicki, JA, Wang, J, Breen, MS, De Rubeis, S, An, JY, Peng, M, Collins, R, Grove, J, Klei, L, Stevens, C, Reichert, J, Mulhern, MS, Artomov, M, Gerges, S, Sheppard, B, Xu, X, Bhaduri, A, Norman, U, Brand, H, Schwartz, G, Nguyen, R, Guerrero, EE, Dias, C, Aleksic, B, Anney, R, Barbosa, M, Bishop, S, Brusco, A, Bybjerg-Grauholm, J, Carracedo, A, Chan, MCY, Chiocchetti, AG, Chung, BHY, Coon, H, Cuccaro, ML, Curró, A, Dalla Bernardina, B, Doan, R, Domenici, E, Dong, S, Fallerini, C, Fernández-Prieto, M, Ferrero, GB
, Nordentoft, M, Werge, T, Appadurai, V, Bækvad-Hansen, M, Hansen, CS, Pedersen, CB, iPSYCH-Broad Consortium & Autism Sequencing Consortium 2020, '
Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism',
Cell, vol. 180, no. 3, pp. 568-584.e23.
https://doi.org/10.1016/j.cell.2019.12.036APA
Satterstrom, F. K., Kosmicki, J. A., Wang, J., Breen, M. S., De Rubeis, S., An, J. Y., Peng, M., Collins, R., Grove, J., Klei, L., Stevens, C., Reichert, J., Mulhern, M. S., Artomov, M., Gerges, S., Sheppard, B., Xu, X., Bhaduri, A., Norman, U., ... Autism Sequencing Consortium (2020).
Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism.
Cell,
180(3), 568-584.e23.
https://doi.org/10.1016/j.cell.2019.12.036Vancouver
Satterstrom FK, Kosmicki JA, Wang J, Breen MS, De Rubeis S, An JY et al.
Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism.
Cell. 2020;180(3):568-584.e23.
https://doi.org/10.1016/j.cell.2019.12.036Author
Satterstrom, F. Kyle ; Kosmicki, Jack A. ; Wang, Jiebiao ; Breen, Michael S. ; De Rubeis, Silvia ; An, Joon Yong ; Peng, Minshi ; Collins, Ryan ; Grove, Jakob ; Klei, Lambertus ; Stevens, Christine ; Reichert, Jennifer ; Mulhern, Maureen S. ; Artomov, Mykyta ; Gerges, Sherif ; Sheppard, Brooke ; Xu, Xinyi ; Bhaduri, Aparna ; Norman, Utku ; Brand, Harrison ; Schwartz, Grace ; Nguyen, Rachel ; Guerrero, Elizabeth E. ; Dias, Caroline ; Aleksic, Branko ; Anney, Richard ; Barbosa, Mafalda ; Bishop, Somer ; Brusco, Alfredo ; Bybjerg-Grauholm, Jonas ; Carracedo, Angel ; Chan, Marcus C.Y. ; Chiocchetti, Andreas G. ; Chung, Brian H.Y. ; Coon, Hilary ; Cuccaro, Michael L. ; Curró, Aurora ; Dalla Bernardina, Bernardo ; Doan, Ryan ; Domenici, Enrico ; Dong, Shan ; Fallerini, Chiara ; Fernández-Prieto, Montserrat ; Ferrero, Giovanni Battista ; Nordentoft, Merete ; Werge, Thomas ; Appadurai, Vivek ; Bækvad-Hansen, Marie ; Hansen, Christine S. ; Pedersen, Carsten Bøcker ; iPSYCH-Broad Consortium ; Autism Sequencing Consortium. / Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism. In: Cell. 2020 ; Vol. 180, No. 3. pp. 568-584.e23.
Bibtex
@article{aff1333faaae491986b379fbc296dc9b,
title = "Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism",
abstract = "Large-scale sequencing of patients with autism allows identification of over 100 putative ASD-associated genes, the majority of which are neuronally expressed, and investigation of distinct genetic influences on ASD compared with other neurodevelopmental disorders.",
keywords = "autism spectrum disorder, cell type, cytoskeleton, excitatory neurons, excitatory-inhibitory balance, exome sequencing, genetics, inhibitory neurons, liability, neurodevelopment",
author = "Satterstrom, {F. Kyle} and Kosmicki, {Jack A.} and Jiebiao Wang and Breen, {Michael S.} and {De Rubeis}, Silvia and An, {Joon Yong} and Minshi Peng and Ryan Collins and Jakob Grove and Lambertus Klei and Christine Stevens and Jennifer Reichert and Mulhern, {Maureen S.} and Mykyta Artomov and Sherif Gerges and Brooke Sheppard and Xinyi Xu and Aparna Bhaduri and Utku Norman and Harrison Brand and Grace Schwartz and Rachel Nguyen and Guerrero, {Elizabeth E.} and Caroline Dias and Branko Aleksic and Richard Anney and Mafalda Barbosa and Somer Bishop and Alfredo Brusco and Jonas Bybjerg-Grauholm and Angel Carracedo and Chan, {Marcus C.Y.} and Chiocchetti, {Andreas G.} and Chung, {Brian H.Y.} and Hilary Coon and Cuccaro, {Michael L.} and Aurora Curr{\'o} and {Dalla Bernardina}, Bernardo and Ryan Doan and Enrico Domenici and Shan Dong and Chiara Fallerini and Montserrat Fern{\'a}ndez-Prieto and Ferrero, {Giovanni Battista} and Merete Nordentoft and Thomas Werge and Vivek Appadurai and Marie B{\ae}kvad-Hansen and Hansen, {Christine S.} and Pedersen, {Carsten B{\o}cker} and {iPSYCH-Broad Consortium} and {Autism Sequencing Consortium}",
year = "2020",
doi = "10.1016/j.cell.2019.12.036",
language = "English",
volume = "180",
pages = "568--584.e23",
journal = "Cell",
issn = "0092-8674",
publisher = "Cell Press",
number = "3",
}
RIS
TY - JOUR
T1 - Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism
AU - Satterstrom, F. Kyle
AU - Kosmicki, Jack A.
AU - Wang, Jiebiao
AU - Breen, Michael S.
AU - De Rubeis, Silvia
AU - An, Joon Yong
AU - Peng, Minshi
AU - Collins, Ryan
AU - Grove, Jakob
AU - Klei, Lambertus
AU - Stevens, Christine
AU - Reichert, Jennifer
AU - Mulhern, Maureen S.
AU - Artomov, Mykyta
AU - Gerges, Sherif
AU - Sheppard, Brooke
AU - Xu, Xinyi
AU - Bhaduri, Aparna
AU - Norman, Utku
AU - Brand, Harrison
AU - Schwartz, Grace
AU - Nguyen, Rachel
AU - Guerrero, Elizabeth E.
AU - Dias, Caroline
AU - Aleksic, Branko
AU - Anney, Richard
AU - Barbosa, Mafalda
AU - Bishop, Somer
AU - Brusco, Alfredo
AU - Bybjerg-Grauholm, Jonas
AU - Carracedo, Angel
AU - Chan, Marcus C.Y.
AU - Chiocchetti, Andreas G.
AU - Chung, Brian H.Y.
AU - Coon, Hilary
AU - Cuccaro, Michael L.
AU - Curró, Aurora
AU - Dalla Bernardina, Bernardo
AU - Doan, Ryan
AU - Domenici, Enrico
AU - Dong, Shan
AU - Fallerini, Chiara
AU - Fernández-Prieto, Montserrat
AU - Ferrero, Giovanni Battista
AU - Nordentoft, Merete
AU - Werge, Thomas
AU - Appadurai, Vivek
AU - Bækvad-Hansen, Marie
AU - Hansen, Christine S.
AU - Pedersen, Carsten Bøcker
AU - iPSYCH-Broad Consortium
AU - Autism Sequencing Consortium
PY - 2020
Y1 - 2020
N2 - Large-scale sequencing of patients with autism allows identification of over 100 putative ASD-associated genes, the majority of which are neuronally expressed, and investigation of distinct genetic influences on ASD compared with other neurodevelopmental disorders.
AB - Large-scale sequencing of patients with autism allows identification of over 100 putative ASD-associated genes, the majority of which are neuronally expressed, and investigation of distinct genetic influences on ASD compared with other neurodevelopmental disorders.
KW - autism spectrum disorder
KW - cell type
KW - cytoskeleton
KW - excitatory neurons
KW - excitatory-inhibitory balance
KW - exome sequencing
KW - genetics
KW - inhibitory neurons
KW - liability
KW - neurodevelopment
U2 - 10.1016/j.cell.2019.12.036
DO - 10.1016/j.cell.2019.12.036
M3 - Journal article
C2 - 31981491
AN - SCOPUS:85078664833
VL - 180
SP - 568-584.e23
JO - Cell
JF - Cell
SN - 0092-8674
IS - 3
ER -
