Is epidermal growth factor involved in development of duodenal polyps in familial polyposis coli?

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Standard

Is epidermal growth factor involved in development of duodenal polyps in familial polyposis coli? / Poulsen, Steen Seier.

In: The American Journal of Gastroenterology, Vol. 83, No. 4, 04.1988, p. 404-6.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Poulsen, SS 1988, 'Is epidermal growth factor involved in development of duodenal polyps in familial polyposis coli?', The American Journal of Gastroenterology, vol. 83, no. 4, pp. 404-6.

APA

Poulsen, S. S. (1988). Is epidermal growth factor involved in development of duodenal polyps in familial polyposis coli? The American Journal of Gastroenterology, 83(4), 404-6.

Vancouver

Poulsen SS. Is epidermal growth factor involved in development of duodenal polyps in familial polyposis coli? The American Journal of Gastroenterology. 1988 Apr;83(4):404-6.

Author

Poulsen, Steen Seier. / Is epidermal growth factor involved in development of duodenal polyps in familial polyposis coli?. In: The American Journal of Gastroenterology. 1988 ; Vol. 83, No. 4. pp. 404-6.

Bibtex

@article{ddb862f83cdf45f8bf587eb040222c9a,
title = "Is epidermal growth factor involved in development of duodenal polyps in familial polyposis coli?",
abstract = "Duodenal adenomas are a frequent extracolonic manifestation in patients with familial polyposis coli (FPC). Epidermal growth factor (EGF), a polypeptide that stimulates cellular growth and differentiation, is localized in Paneth cells in the small intestine. In two patients with FPC, we found EGF immunoreactivity in duodenal adenomas. Numerous EGF immunoreactive Paneth cells were localized, not as usually, in the bottom of the crypts, but scattered along the crypts alone or in clusters. We do not know whether EGF is involved in the development of duodenal polyps in FPC patients, or whether the present findings represent secondary changes in duodenal polyps.",
keywords = "Adenoma, Adenomatous Polyposis Coli, Adult, Duodenal Neoplasms, Duodenum, Epidermal Growth Factor, Female, Humans, Hyperplasia, Intestinal Mucosa, Intestinal Polyps, Male, Neoplasms, Multiple Primary",
author = "Poulsen, {Steen Seier}",
year = "1988",
month = apr,
language = "English",
volume = "83",
pages = "404--6",
journal = "The American Journal of Gastroenterology",
issn = "0002-9270",
publisher = "nature publishing group",
number = "4",

}

RIS

TY - JOUR

T1 - Is epidermal growth factor involved in development of duodenal polyps in familial polyposis coli?

AU - Poulsen, Steen Seier

PY - 1988/4

Y1 - 1988/4

N2 - Duodenal adenomas are a frequent extracolonic manifestation in patients with familial polyposis coli (FPC). Epidermal growth factor (EGF), a polypeptide that stimulates cellular growth and differentiation, is localized in Paneth cells in the small intestine. In two patients with FPC, we found EGF immunoreactivity in duodenal adenomas. Numerous EGF immunoreactive Paneth cells were localized, not as usually, in the bottom of the crypts, but scattered along the crypts alone or in clusters. We do not know whether EGF is involved in the development of duodenal polyps in FPC patients, or whether the present findings represent secondary changes in duodenal polyps.

AB - Duodenal adenomas are a frequent extracolonic manifestation in patients with familial polyposis coli (FPC). Epidermal growth factor (EGF), a polypeptide that stimulates cellular growth and differentiation, is localized in Paneth cells in the small intestine. In two patients with FPC, we found EGF immunoreactivity in duodenal adenomas. Numerous EGF immunoreactive Paneth cells were localized, not as usually, in the bottom of the crypts, but scattered along the crypts alone or in clusters. We do not know whether EGF is involved in the development of duodenal polyps in FPC patients, or whether the present findings represent secondary changes in duodenal polyps.

KW - Adenoma

KW - Adenomatous Polyposis Coli

KW - Adult

KW - Duodenal Neoplasms

KW - Duodenum

KW - Epidermal Growth Factor

KW - Female

KW - Humans

KW - Hyperplasia

KW - Intestinal Mucosa

KW - Intestinal Polyps

KW - Male

KW - Neoplasms, Multiple Primary

M3 - Journal article

C2 - 2831708

VL - 83

SP - 404

EP - 406

JO - The American Journal of Gastroenterology

JF - The American Journal of Gastroenterology

SN - 0002-9270

IS - 4

ER -

ID: 47488382