Intralymfatisk allergenspecifik immunterapi
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Intralymfatisk allergenspecifik immunterapi. / Næraa, Sara Haunstrup; Schollert, Niels-Erik Harbo; Flader Skov, Peter Nytofte; Homøe, Preben.
In: Ugeskrift for Laeger, Vol. 180, No. 22, V09170695, 2018.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Intralymfatisk allergenspecifik immunterapi
AU - Næraa, Sara Haunstrup
AU - Schollert, Niels-Erik Harbo
AU - Flader Skov, Peter Nytofte
AU - Homøe, Preben
PY - 2018
Y1 - 2018
N2 - An emerging method for allergen-specific immunotherapy is intralymphatic placement, which only requires three injections with intervals of four weeks. In this review, we summarise available evidence on clinical safety, biological efficacy and therapeutic outcomes. The treatment appears to be safe with only few and mild adverse reactions. The immunological activation profile is comparable to that known for subcutaneous therapy. Clinically, patients experienced fewer symptoms with less medication use with intralymphatic allergen-specific immunotherapy than with other types of immunotherapy. The number of studies is limited, and the studies have important limitations. More phase 3 studies are needed in order to make a conclusion.
AB - An emerging method for allergen-specific immunotherapy is intralymphatic placement, which only requires three injections with intervals of four weeks. In this review, we summarise available evidence on clinical safety, biological efficacy and therapeutic outcomes. The treatment appears to be safe with only few and mild adverse reactions. The immunological activation profile is comparable to that known for subcutaneous therapy. Clinically, patients experienced fewer symptoms with less medication use with intralymphatic allergen-specific immunotherapy than with other types of immunotherapy. The number of studies is limited, and the studies have important limitations. More phase 3 studies are needed in order to make a conclusion.
M3 - Tidsskriftartikel
C2 - 29808813
VL - 180
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 22
M1 - V09170695
ER -
ID: 222248033