Ink-jet printing of pharmaceuticals
Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
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Ink-jet printing of pharmaceuticals. / Takala, M.; Helkiö, H.; Sundholm, J.; Genina, N.; Kiviluoma, P.; Widmaier, T.; Sandler, N.; Kuosmanen, P.
Proceedings of the International Conference of DAAAM Baltic. DAAAM International, 2012. p. 233-239 (Proceedings of the International Conference of DAAAM Baltic).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
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TY - GEN
T1 - Ink-jet printing of pharmaceuticals
AU - Takala, M.
AU - Helkiö, H.
AU - Sundholm, J.
AU - Genina, N.
AU - Kiviluoma, P.
AU - Widmaier, T.
AU - Sandler, N.
AU - Kuosmanen, P.
PY - 2012/1/1
Y1 - 2012/1/1
N2 - Traditional tablet manufacturing process has multiple powder handling and mixing phases. It is time consuming and limits individualized dosing. Furthermore, uniformity of the dose is difficult to achieve. Modern ink-jet printing technology has been successfully applied to polymer electronics and biomaterial applications. It has many advantages that could be utilized in drug manufacturing process, such as faster production cycle with fewer processing steps, precise dosing, on-demand individualized dosing and possibility for on-line quality control. This study examines how well current printer technologies function in printing different types of drug solutions on paper-like substrate. Preliminary tests were carried out with paracetamol and riboflavin-water solutions. The study denoted that printing medicines and bio-polymer coating was possible, the accuracy of dose was very satisfying and personalized dosing was easy to achieve. Further studies with specially manufactured printers are still needed to determine the suitability of the ink-jet printing process in commercial drug manufacturing.
AB - Traditional tablet manufacturing process has multiple powder handling and mixing phases. It is time consuming and limits individualized dosing. Furthermore, uniformity of the dose is difficult to achieve. Modern ink-jet printing technology has been successfully applied to polymer electronics and biomaterial applications. It has many advantages that could be utilized in drug manufacturing process, such as faster production cycle with fewer processing steps, precise dosing, on-demand individualized dosing and possibility for on-line quality control. This study examines how well current printer technologies function in printing different types of drug solutions on paper-like substrate. Preliminary tests were carried out with paracetamol and riboflavin-water solutions. The study denoted that printing medicines and bio-polymer coating was possible, the accuracy of dose was very satisfying and personalized dosing was easy to achieve. Further studies with specially manufactured printers are still needed to determine the suitability of the ink-jet printing process in commercial drug manufacturing.
KW - Paracetamol
KW - Personalized dosing
KW - Piezoelectric
KW - Print head
KW - Riboflavin
KW - Thermal
UR - http://www.scopus.com/inward/record.url?scp=84920547023&partnerID=8YFLogxK
M3 - Article in proceedings
AN - SCOPUS:84920547023
T3 - Proceedings of the International Conference of DAAAM Baltic
SP - 233
EP - 239
BT - Proceedings of the International Conference of DAAAM Baltic
PB - DAAAM International
T2 - 8th International DAAAM Baltic Conference: Industrial Engineering
Y2 - 19 April 2012 through 21 April 2012
ER -
ID: 241206263