Induction of oxygen free radical generation in human monocytes by lipoprotein(a)
Research output: Contribution to journal › Journal article › Research › peer-review
The mechanism behind the association of elevated plasma lipoprotein(a) [Lp(a)] levels with atherosclerotic disease is unknown. In the present study, Lp(a) induced generation of oxygen free radicals by monocytes from selected healthy individuals in vitro. This observation may provide a link between Lp(a) and generation of oxidized LDL, which can promote multiple atherogenic cellular responses.
| Original language | English |
|---|---|
| Journal | European Journal of Clinical Investigation |
| Volume | 24 |
| Issue number | 7 |
| Pages (from-to) | 497-9 |
| Number of pages | 2 |
| ISSN | 0014-2972 |
| Publication status | Published - 1994 |
Bibliographical note
Keywords: Chemiluminescent Measurements; Female; Humans; Lipoprotein(a); Male; Monocytes; Reactive Oxygen Species; Respiratory Burst
ID: 18106831