In silico product design of pharmaceuticals
Research output: Contribution to journal › Journal article › Research › peer-review
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In silico product design of pharmaceuticals. / Boetker, Johan; Raijada, Dhara; Aho, Johanna; Khorasani, Milad; Søgaard, Søren Vinter; Arnfast, Lærke; Bohr, Adam; Edinger, Magnus; Water, Jorrit; Rantanen, Jukka.
In: Asian Journal of Pharmaceutical Sciences, Vol. 11, No. 4, 2016, p. 492–499.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - In silico product design of pharmaceuticals
AU - Boetker, Johan
AU - Raijada, Dhara
AU - Aho, Johanna
AU - Khorasani, Milad
AU - Søgaard, Søren Vinter
AU - Arnfast, Lærke
AU - Bohr, Adam
AU - Edinger, Magnus
AU - Water, Jorrit
AU - Rantanen, Jukka
PY - 2016
Y1 - 2016
N2 - Abstract The increasing demand for personalized medicine necessitates the production of easily customizable dosage forms. As the number of possible dosage forms may scale towards infinity, their uniqueness require a versatile production platform and numerical simulation in order to be manufactured efficiently. A mathematical description of these systems is the only feasible approach to manage such diverse properties of different products. However, experimental verification is still essential for evaluation of processability and related concomitant phenomena, such as possible solid state changes that may occur during production and storage.
AB - Abstract The increasing demand for personalized medicine necessitates the production of easily customizable dosage forms. As the number of possible dosage forms may scale towards infinity, their uniqueness require a versatile production platform and numerical simulation in order to be manufactured efficiently. A mathematical description of these systems is the only feasible approach to manage such diverse properties of different products. However, experimental verification is still essential for evaluation of processability and related concomitant phenomena, such as possible solid state changes that may occur during production and storage.
KW - Personalized medicine
KW - simulation
KW - rheology
KW - imaging
KW - continuous manufacturing
KW - extrusion
U2 - 10.1016/j.ajps.2016.02.010
DO - 10.1016/j.ajps.2016.02.010
M3 - Tidsskriftartikel
VL - 11
SP - 492
EP - 499
JO - Asian Journal of Pharmaceutical Sciences
JF - Asian Journal of Pharmaceutical Sciences
SN - 1818-0876
IS - 4
ER -
ID: 160046488