Identification and characterization of a small-molecule inhibitor of death-associated protein kinase 1
Research output: Contribution to journal › Journal article › Research › peer-review
A novel imidazo-pyramidazine inhibitor of DAPK1 that undergoes class-specific interactions and extends into the substrate recognition site has been identified. This inhibitor is a good starting point for the development of selective and potent inhibitors of DAPK1, with potential use against stroke and ischemia.
| Original language | English |
|---|---|
| Journal | ChemBioChem |
| Volume | 16 |
| Issue number | 1 |
| Pages (from-to) | 59-63 |
| Number of pages | 5 |
| ISSN | 1439-4227 |
| DOIs | |
| Publication status | Published - 2 Jan 2015 |
ID: 138769080