Hypersensitivity reactions to human albumin—A case series and diagnostic algorithm

Research output: Contribution to journal › Letter › Research › peer-review

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Hypersensitivity reactions to human albumin—A case series and diagnostic algorithm. / Basu, Millie Nguyen; Melchiors, Birgitte Bech; Mortz, Charlotte G.; Garvey, Lene H.

In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 79, No. 3, 2024, p. 752-754.

Research output: Contribution to journal › Letter › Research › peer-review

Harvard

Basu, MN, Melchiors, BB, Mortz, CG & Garvey, LH 2024, 'Hypersensitivity reactions to human albumin—A case series and diagnostic algorithm', Allergy: European Journal of Allergy and Clinical Immunology, vol. 79, no. 3, pp. 752-754. https://doi.org/10.1111/all.15971

APA

Basu, M. N., Melchiors, B. B., Mortz, C. G., & Garvey, L. H. (2024). Hypersensitivity reactions to human albumin—A case series and diagnostic algorithm. Allergy: European Journal of Allergy and Clinical Immunology, 79(3), 752-754. https://doi.org/10.1111/all.15971

Vancouver

Basu MN, Melchiors BB, Mortz CG, Garvey LH. Hypersensitivity reactions to human albumin—A case series and diagnostic algorithm. Allergy: European Journal of Allergy and Clinical Immunology. 2024;79(3):752-754. https://doi.org/10.1111/all.15971

Author

Basu, Millie Nguyen ; Melchiors, Birgitte Bech ; Mortz, Charlotte G. ; Garvey, Lene H. / Hypersensitivity reactions to human albumin—A case series and diagnostic algorithm. In: Allergy: European Journal of Allergy and Clinical Immunology. 2024 ; Vol. 79, No. 3. pp. 752-754.

Bibtex

@article{e13e959971a94a10b29c75664afc6544,
title = "Hypersensitivity reactions to human albumin—A case series and diagnostic algorithm",
abstract = "Albumin is a protein produced by the liver and comprises 60% of proteins in human plasma. Human albumin (HA) is used in clinical practice for its oncotic and plasma-expanding properties. Non-allergic reactions precipitated by aggregation or denaturation of HA are described in the literature.1, 2 However, IgE-mediated allergic reactions to human albumin are extremely rare and only a handful of cases have been reported.3-5 Different diagnostic investigations are described, and standardization is lacking. We report a series of cases comprising five patients with hypersensitivity to HA and suggest a diagnostic algorithm.",
author = "Basu, {Millie Nguyen} and Melchiors, {Birgitte Bech} and Mortz, {Charlotte G.} and Garvey, {Lene H.}",
year = "2024",
doi = "10.1111/all.15971",
language = "English",
volume = "79",
pages = "752--754",
journal = "Allergy: European Journal of Allergy and Clinical Immunology",
issn = "0105-4538",
publisher = "Wiley Online",
number = "3",

}

RIS

TY - JOUR

T1 - Hypersensitivity reactions to human albumin—A case series and diagnostic algorithm

AU - Basu, Millie Nguyen

AU - Melchiors, Birgitte Bech

AU - Mortz, Charlotte G.

AU - Garvey, Lene H.

PY - 2024

Y1 - 2024

N2 - Albumin is a protein produced by the liver and comprises 60% of proteins in human plasma. Human albumin (HA) is used in clinical practice for its oncotic and plasma-expanding properties. Non-allergic reactions precipitated by aggregation or denaturation of HA are described in the literature.1, 2 However, IgE-mediated allergic reactions to human albumin are extremely rare and only a handful of cases have been reported.3-5 Different diagnostic investigations are described, and standardization is lacking. We report a series of cases comprising five patients with hypersensitivity to HA and suggest a diagnostic algorithm.

AB - Albumin is a protein produced by the liver and comprises 60% of proteins in human plasma. Human albumin (HA) is used in clinical practice for its oncotic and plasma-expanding properties. Non-allergic reactions precipitated by aggregation or denaturation of HA are described in the literature.1, 2 However, IgE-mediated allergic reactions to human albumin are extremely rare and only a handful of cases have been reported.3-5 Different diagnostic investigations are described, and standardization is lacking. We report a series of cases comprising five patients with hypersensitivity to HA and suggest a diagnostic algorithm.

U2 - 10.1111/all.15971

DO - 10.1111/all.15971

M3 - Letter

C2 - 38102983

AN - SCOPUS:85179947658

VL - 79

SP - 752

EP - 754

JO - Allergy: European Journal of Allergy and Clinical Immunology

JF - Allergy: European Journal of Allergy and Clinical Immunology

SN - 0105-4538

IS - 3

ER -

ID: 385693942