Heterogeneity and plasticity of epidermal stem cells

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Heterogeneity and plasticity of epidermal stem cells. / Schepeler, Troels; Page, Mahalia E; Jensen, Kim Bak.

In: Development (Cambridge, England), Vol. 141, No. 13, 07.2014, p. 2559-2567.

Research output: Contribution to journalReviewResearchpeer-review

Harvard

Schepeler, T, Page, ME & Jensen, KB 2014, 'Heterogeneity and plasticity of epidermal stem cells', Development (Cambridge, England), vol. 141, no. 13, pp. 2559-2567. https://doi.org/10.1242/dev.104588

APA

Schepeler, T., Page, M. E., & Jensen, K. B. (2014). Heterogeneity and plasticity of epidermal stem cells. Development (Cambridge, England), 141(13), 2559-2567. https://doi.org/10.1242/dev.104588

Vancouver

Schepeler T, Page ME, Jensen KB. Heterogeneity and plasticity of epidermal stem cells. Development (Cambridge, England). 2014 Jul;141(13):2559-2567. https://doi.org/10.1242/dev.104588

Author

Schepeler, Troels ; Page, Mahalia E ; Jensen, Kim Bak. / Heterogeneity and plasticity of epidermal stem cells. In: Development (Cambridge, England). 2014 ; Vol. 141, No. 13. pp. 2559-2567.

Bibtex

@article{daa4ad51cc21491fa7291c099984a6b1,
title = "Heterogeneity and plasticity of epidermal stem cells",
abstract = "The epidermis is an integral part of our largest organ, the skin, and protects us against the hostile environment. It is a highly dynamic tissue that, during normal steady-state conditions, undergoes constant turnover. Multiple stem cell populations residing in autonomously maintained compartments facilitate this task. In this Review, we discuss stem cell behaviour during normal tissue homeostasis, regeneration and disease within the pilosebaceous unit, an integral structure of the epidermis that is responsible for hair growth and lubrication of the epithelium. We provide an up-to-date view of the pilosebaceous unit, encompassing the heterogeneity and plasticity of multiple discrete stem cell populations that are strongly influenced by external cues to maintain their identity and function.",
author = "Troels Schepeler and Page, {Mahalia E} and Jensen, {Kim Bak}",
note = "{\textcopyright} 2014. Published by The Company of Biologists Ltd.",
year = "2014",
month = jul,
doi = "10.1242/dev.104588",
language = "English",
volume = "141",
pages = "2559--2567",
journal = "Development",
issn = "0950-1991",
publisher = "The Company of Biologists",
number = "13",

}

RIS

TY - JOUR

T1 - Heterogeneity and plasticity of epidermal stem cells

AU - Schepeler, Troels

AU - Page, Mahalia E

AU - Jensen, Kim Bak

N1 - © 2014. Published by The Company of Biologists Ltd.

PY - 2014/7

Y1 - 2014/7

N2 - The epidermis is an integral part of our largest organ, the skin, and protects us against the hostile environment. It is a highly dynamic tissue that, during normal steady-state conditions, undergoes constant turnover. Multiple stem cell populations residing in autonomously maintained compartments facilitate this task. In this Review, we discuss stem cell behaviour during normal tissue homeostasis, regeneration and disease within the pilosebaceous unit, an integral structure of the epidermis that is responsible for hair growth and lubrication of the epithelium. We provide an up-to-date view of the pilosebaceous unit, encompassing the heterogeneity and plasticity of multiple discrete stem cell populations that are strongly influenced by external cues to maintain their identity and function.

AB - The epidermis is an integral part of our largest organ, the skin, and protects us against the hostile environment. It is a highly dynamic tissue that, during normal steady-state conditions, undergoes constant turnover. Multiple stem cell populations residing in autonomously maintained compartments facilitate this task. In this Review, we discuss stem cell behaviour during normal tissue homeostasis, regeneration and disease within the pilosebaceous unit, an integral structure of the epidermis that is responsible for hair growth and lubrication of the epithelium. We provide an up-to-date view of the pilosebaceous unit, encompassing the heterogeneity and plasticity of multiple discrete stem cell populations that are strongly influenced by external cues to maintain their identity and function.

U2 - 10.1242/dev.104588

DO - 10.1242/dev.104588

M3 - Review

C2 - 24961797

VL - 141

SP - 2559

EP - 2567

JO - Development

JF - Development

SN - 0950-1991

IS - 13

ER -

ID: 118031559