Genetically lowered microsomal epoxide hydrolase activity and tobacco-related cancer in 47,000 individuals
Research output: Contribution to journal › Journal article › Research › peer-review
Two functional polymorphisms of the microsomal epoxide hydrolase (mEH) gene (EPHX1), Tyr113His (rs1051740) and His139Arg (rs2234922), have variably been found to influence susceptibility to various cancer forms. We tested whether genetically lowered mEH activity affects risk of developing cancer in the general population.
| Original language | English |
|---|---|
| Journal | Cancer Epidemiology, Biomarkers & Prevention |
| Volume | 20 |
| Issue number | 8 |
| Pages (from-to) | 1673-82 |
| Number of pages | 10 |
| ISSN | 1055-9965 |
| DOIs | |
| Publication status | Published - 2011 |
- Aged, Cocarcinogenesis, Denmark, Epoxide Hydrolases, Female, Genetic Predisposition to Disease, Genotype, Humans, Male, Middle Aged, Neoplasms, Questionnaires, Smoking
Research areas
ID: 40184301