Genetic profiling of intrahepatic cholangiocarcinoma
Research output: Contribution to journal › Review › Research › peer-review
Intrahepatic cholangiocarcinoma (ICC) is a treatment-refractory disease with a dismal outcome. Limited success in the clinical management and a persistent increase in the incidence world-wide have made ICC one of the most lethal and fastest growing malignancies. However, recent advancements in genome-wide technologies combined with the application of integrative multidimensional analytical approaches have begun to provide both detailed insight into the underlying biological traits of ICC and identified new therapeutic opportunities.
Original language | English |
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Journal | Current Opinion in Gastroenterology |
Volume | 28 |
Issue number | 3 |
Pages (from-to) | 266-72 |
Number of pages | 7 |
ISSN | 0267-1379 |
DOIs | |
Publication status | Published - May 2012 |
Externally published | Yes |
- Anti-Inflammatory Agents, Cholangiocarcinoma, DNA Mutational Analysis, Drug Therapy, Combination, Female, Gene Expression Profiling, Genes, ras, Genome-Wide Association Study, Humans, Liver Neoplasms, Male, Mutation, Patient Selection, Prognosis, Pyrazoles, Pyrimidines, Risk Factors
Research areas
ID: 97138638