Flagellotropic phages

Research

Flagellotropic phages: common yet diverse host interaction strategies

Research output: Contribution to journal › Review › Research › peer-review

Standard

Flagellotropic phages : common yet diverse host interaction strategies. / Gambino, Michela; Sørensen, Martine C.H.

In: Current Opinion in Microbiology, Vol. 78, 102451, 2024.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Gambino, M & Sørensen, MCH 2024, 'Flagellotropic phages: common yet diverse host interaction strategies', Current Opinion in Microbiology, vol. 78, 102451. https://doi.org/10.1016/j.mib.2024.102451

APA

Gambino, M., & Sørensen, M. C. H. (2024). Flagellotropic phages: common yet diverse host interaction strategies. Current Opinion in Microbiology, 78, [102451]. https://doi.org/10.1016/j.mib.2024.102451

Vancouver

Gambino M, Sørensen MCH. Flagellotropic phages: common yet diverse host interaction strategies. Current Opinion in Microbiology. 2024;78. 102451. https://doi.org/10.1016/j.mib.2024.102451

Author

Gambino, Michela ; Sørensen, Martine C.H. / Flagellotropic phages : common yet diverse host interaction strategies. In: Current Opinion in Microbiology. 2024 ; Vol. 78.

Bibtex

@article{e4da85c41bff451ba0f1ccb888ca33ab,

title = "Flagellotropic phages: common yet diverse host interaction strategies",

abstract = "Many bacteriophages (phages) interact with flagella and rely on bacterial motility for successful infection of their hosts. Yet, limited information is available on how phages have evolved to recognize and bind both flagella and subsequent surface receptors for phage DNA injection. Here, we present an update on the current knowledge of flagellotropic phages using a few well-studied phages as examples to unravel the molecular details of bacterial host recognition. We discuss the recent advances in the role of globular exposed flagellin domains and flagella glycosylation in phage binding to the flagella. In addition, we present diverse types of surface receptors and phage components responsible for the interaction with the host. Finally, we point to questions remaining to be answered and new approaches to study this unique group of phages.",

author = "Michela Gambino and S{\o}rensen, {Martine C.H.}",

note = "Publisher Copyright: {\textcopyright} 2024 The Authors",

year = "2024",

doi = "10.1016/j.mib.2024.102451",

language = "English",

volume = "78",

journal = "Current Opinion in Microbiology",

issn = "1369-5274",

publisher = "Elsevier Ltd. * Current Opinion Journals",

}

RIS

TY - JOUR

T1 - Flagellotropic phages

T2 - common yet diverse host interaction strategies

AU - Gambino, Michela

AU - Sørensen, Martine C.H.

PY - 2024

Y1 - 2024

N2 - Many bacteriophages (phages) interact with flagella and rely on bacterial motility for successful infection of their hosts. Yet, limited information is available on how phages have evolved to recognize and bind both flagella and subsequent surface receptors for phage DNA injection. Here, we present an update on the current knowledge of flagellotropic phages using a few well-studied phages as examples to unravel the molecular details of bacterial host recognition. We discuss the recent advances in the role of globular exposed flagellin domains and flagella glycosylation in phage binding to the flagella. In addition, we present diverse types of surface receptors and phage components responsible for the interaction with the host. Finally, we point to questions remaining to be answered and new approaches to study this unique group of phages.

AB - Many bacteriophages (phages) interact with flagella and rely on bacterial motility for successful infection of their hosts. Yet, limited information is available on how phages have evolved to recognize and bind both flagella and subsequent surface receptors for phage DNA injection. Here, we present an update on the current knowledge of flagellotropic phages using a few well-studied phages as examples to unravel the molecular details of bacterial host recognition. We discuss the recent advances in the role of globular exposed flagellin domains and flagella glycosylation in phage binding to the flagella. In addition, we present diverse types of surface receptors and phage components responsible for the interaction with the host. Finally, we point to questions remaining to be answered and new approaches to study this unique group of phages.

U2 - 10.1016/j.mib.2024.102451

DO - 10.1016/j.mib.2024.102451

M3 - Review

C2 - 38452595

AN - SCOPUS:85187010680

VL - 78

JO - Current Opinion in Microbiology

JF - Current Opinion in Microbiology

SN - 1369-5274

M1 - 102451

ER -

ID: 385586996