Fibronectin distribution during the development of fetal rat skin.

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Standard

Fibronectin distribution during the development of fetal rat skin. / Gibson, W T; Couchman, J R; Weaver, A C.

In: Journal of Investigative Dermatology, Vol. 81, No. 6, 1983, p. 480-5.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Gibson, WT, Couchman, JR & Weaver, AC 1983, 'Fibronectin distribution during the development of fetal rat skin.', Journal of Investigative Dermatology, vol. 81, no. 6, pp. 480-5.

APA

Gibson, W. T., Couchman, J. R., & Weaver, A. C. (1983). Fibronectin distribution during the development of fetal rat skin. Journal of Investigative Dermatology, 81(6), 480-5.

Vancouver

Gibson WT, Couchman JR, Weaver AC. Fibronectin distribution during the development of fetal rat skin. Journal of Investigative Dermatology. 1983;81(6):480-5.

Author

Gibson, W T ; Couchman, J R ; Weaver, A C. / Fibronectin distribution during the development of fetal rat skin. In: Journal of Investigative Dermatology. 1983 ; Vol. 81, No. 6. pp. 480-5.

Bibtex

@article{08f87940598f11dd8d9f000ea68e967b,
title = "Fibronectin distribution during the development of fetal rat skin.",
abstract = "Fibronectin distribution during fetal rat skin development has been studied immunocytochemically at the light and electron microscope level from 16 days of gestation to birth. The dermal-epidermal junction, the dermis, and connective tissue around developing muscle were shown by light microscopy to be heavily stained throughout this period. The development of hair follicles from about 18 days onward was not associated with any consistent change in fibronectin distribution. The heavy staining of the upper dermis was associated with a high density of mesenchymal cells, and immunoelectron microscopy revealed fibronectin on the surface of many of these cells and in association with the surrounding fine collagen fibrils. At the dermal-epidermal junction, both follicular and interfollicular, fibronectin was localized mainly in the plasma membrane and lamina lucida regions of the basement membrane, and there was also staining associated with the underlying fine collagen fibrils. These observations are further evidence for the proposed role of fibronectin as a mediator of the cell-matrix interactions which are of importance for tissue development and maintenance.",
author = "Gibson, {W T} and Couchman, {J R} and Weaver, {A C}",
note = "Keywords: Animals; Basement Membrane; Cell Membrane; Collagen; Epidermis; Fibronectins; Gestational Age; Immunoenzyme Techniques; Microscopy, Electron; Rats; Rats, Inbred Strains; Skin; Tissue Distribution",
year = "1983",
language = "English",
volume = "81",
pages = "480--5",
journal = "Journal of Investigative Dermatology",
issn = "0022-202X",
publisher = "nature publishing group",
number = "6",

}

RIS

TY - JOUR

T1 - Fibronectin distribution during the development of fetal rat skin.

AU - Gibson, W T

AU - Couchman, J R

AU - Weaver, A C

N1 - Keywords: Animals; Basement Membrane; Cell Membrane; Collagen; Epidermis; Fibronectins; Gestational Age; Immunoenzyme Techniques; Microscopy, Electron; Rats; Rats, Inbred Strains; Skin; Tissue Distribution

PY - 1983

Y1 - 1983

N2 - Fibronectin distribution during fetal rat skin development has been studied immunocytochemically at the light and electron microscope level from 16 days of gestation to birth. The dermal-epidermal junction, the dermis, and connective tissue around developing muscle were shown by light microscopy to be heavily stained throughout this period. The development of hair follicles from about 18 days onward was not associated with any consistent change in fibronectin distribution. The heavy staining of the upper dermis was associated with a high density of mesenchymal cells, and immunoelectron microscopy revealed fibronectin on the surface of many of these cells and in association with the surrounding fine collagen fibrils. At the dermal-epidermal junction, both follicular and interfollicular, fibronectin was localized mainly in the plasma membrane and lamina lucida regions of the basement membrane, and there was also staining associated with the underlying fine collagen fibrils. These observations are further evidence for the proposed role of fibronectin as a mediator of the cell-matrix interactions which are of importance for tissue development and maintenance.

AB - Fibronectin distribution during fetal rat skin development has been studied immunocytochemically at the light and electron microscope level from 16 days of gestation to birth. The dermal-epidermal junction, the dermis, and connective tissue around developing muscle were shown by light microscopy to be heavily stained throughout this period. The development of hair follicles from about 18 days onward was not associated with any consistent change in fibronectin distribution. The heavy staining of the upper dermis was associated with a high density of mesenchymal cells, and immunoelectron microscopy revealed fibronectin on the surface of many of these cells and in association with the surrounding fine collagen fibrils. At the dermal-epidermal junction, both follicular and interfollicular, fibronectin was localized mainly in the plasma membrane and lamina lucida regions of the basement membrane, and there was also staining associated with the underlying fine collagen fibrils. These observations are further evidence for the proposed role of fibronectin as a mediator of the cell-matrix interactions which are of importance for tissue development and maintenance.

M3 - Journal article

C2 - 6358375

VL - 81

SP - 480

EP - 485

JO - Journal of Investigative Dermatology

JF - Journal of Investigative Dermatology

SN - 0022-202X

IS - 6

ER -

ID: 5167786