Expression of the vitamin D receptor, 25-hydroxylases, 1alpha-hydroxylase and 24-hydroxylase in the human kidney and renal clear cell cancer
Research output: Contribution to journal › Journal article › Research › peer-review
The vitamin D receptor (VDR), CYP27B1 and CYP24A1 are expressed in the human kidney, but the segmental expression of the 25-hydroxylases is unknown. A comprehensive analysis of CYP2R1, CYP27A1, CYP27B1, VDR and CYP24A1 expression in normal kidney and renal clear cell cancer (CCc) would reveal the segmental location of expression, and clarify whether the reported loss of VDR in CCc is coincident with alterations of vitamin D metabolism.
| Original language | English |
|---|---|
| Journal | Journal of Steroid Biochemistry and Molecular Biology |
| Volume | 121 |
| Issue number | 1-2 |
| Pages (from-to) | 376-82 |
| Number of pages | 7 |
| ISSN | 0960-0760 |
| DOIs | |
| Publication status | Published - 1 Jul 2010 |
ID: 34048132