Exploring protective and risk factors in the home environment in high-risk families – results from the Danish High Risk and Resilience Study—VIA 7
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Exploring protective and risk factors in the home environment in high-risk families – results from the Danish High Risk and Resilience Study—VIA 7. / Thorup, Anne Amalie Elgaard; Gantriis, Ditte Lou; Greve, Aja Neergaard; Henriksen, Maria Toft; Zahle, Kate Kold; Stadsgaard, Henriette; Ellersgaard, Ditte; Burton, Birgitte Klee; Christiani, Camilla Jerlang; Spang, Katrine; Hemager, Nicoline; Jepsen, Jens Richardt Møllegaard; Plessen, Kerstin J.; Nordentoft, Merete; Mors, Ole; Bliksted, Vibeke.
In: BMC Psychiatry, Vol. 22, 100, 2022.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Exploring protective and risk factors in the home environment in high-risk families – results from the Danish High Risk and Resilience Study—VIA 7
AU - Thorup, Anne Amalie Elgaard
AU - Gantriis, Ditte Lou
AU - Greve, Aja Neergaard
AU - Henriksen, Maria Toft
AU - Zahle, Kate Kold
AU - Stadsgaard, Henriette
AU - Ellersgaard, Ditte
AU - Burton, Birgitte Klee
AU - Christiani, Camilla Jerlang
AU - Spang, Katrine
AU - Hemager, Nicoline
AU - Jepsen, Jens Richardt Møllegaard
AU - Plessen, Kerstin J.
AU - Nordentoft, Merete
AU - Mors, Ole
AU - Bliksted, Vibeke
N1 - Publisher Copyright: © 2022, The Author(s).
PY - 2022
Y1 - 2022
N2 - Background: Exposure to inadequate home environment may put the healthy development of familial high-risk children at risk. This study aimed to investigate associations between risk factors and an adequate home environment of children having a parent diagnosed with schizophrenia or bipolar disorder. Methods: From a cohort of 522 children, data from 463 7-year-old children was included. Of these 172 children had familial risk for schizophrenia, 109 children had familial risk for bipolar disorder, and 190 were population-based controls. As part of a comprehensive battery, all participants were assessed with the Middle Childhood-Home Observation for Measurement of the Environment Inventory (MC-HOME Inventory) measuring the quality of the home environment. Results: When analyzing all families together, we found that having a parent diagnosed with schizophrenia would have a negative impact on the home environment (ß = -1.08; 95% CI (-2.16;-0.01); p = 0.05), while familial risk for bipolar disorder did not show significant predictive value. Being a single caregiver and child having experienced severe life events from ages 4 to 7 showed significant negative impact, while child having a mental illness diagnosis did not. Being a female caregiver, good social functioning of the caregiver, high child IQ and not being a single caregiver were found to predict positive values for the home environment. We found similar results when analyzing caregivers with and without a diagnosis separately. Conclusions: Knowledge of what predicts good home environment should be used to inform development of early interventions for families at risk.
AB - Background: Exposure to inadequate home environment may put the healthy development of familial high-risk children at risk. This study aimed to investigate associations between risk factors and an adequate home environment of children having a parent diagnosed with schizophrenia or bipolar disorder. Methods: From a cohort of 522 children, data from 463 7-year-old children was included. Of these 172 children had familial risk for schizophrenia, 109 children had familial risk for bipolar disorder, and 190 were population-based controls. As part of a comprehensive battery, all participants were assessed with the Middle Childhood-Home Observation for Measurement of the Environment Inventory (MC-HOME Inventory) measuring the quality of the home environment. Results: When analyzing all families together, we found that having a parent diagnosed with schizophrenia would have a negative impact on the home environment (ß = -1.08; 95% CI (-2.16;-0.01); p = 0.05), while familial risk for bipolar disorder did not show significant predictive value. Being a single caregiver and child having experienced severe life events from ages 4 to 7 showed significant negative impact, while child having a mental illness diagnosis did not. Being a female caregiver, good social functioning of the caregiver, high child IQ and not being a single caregiver were found to predict positive values for the home environment. We found similar results when analyzing caregivers with and without a diagnosis separately. Conclusions: Knowledge of what predicts good home environment should be used to inform development of early interventions for families at risk.
KW - Bipolar disorder
KW - Familial high-risk
KW - Home environment
KW - Risk factors
KW - Schizophrenia
U2 - 10.1186/s12888-022-03733-5
DO - 10.1186/s12888-022-03733-5
M3 - Journal article
C2 - 35139818
AN - SCOPUS:85124263083
VL - 22
JO - B M C Psychiatry
JF - B M C Psychiatry
SN - 1471-244X
M1 - 100
ER -
ID: 299556050