Estimating drop-out probabilities of STR alleles accounting for stutters, detection threshold truncation and degradation

Research output: Contribution to journalJournal articleResearchpeer-review

Allelic drop-out continues to be a challenge to forensic geneticists when interpreting crime scene evidence and calculating the evidential weight. Methods exist for estimating the probability of allelic drop-out, where the most promising methods use the signal intensities as input for quantifying the drop-out probability. Using data from real crime cases, we demonstrate that taking degradation of the biological material and truncation of the data due to a detection threshold into account is superior to previous approaches. An additional correction for stuttering effects showed limited improvement.

Original languageEnglish
JournalForensic Science International: Genetics Supplement Series
Volume4
Issue number1
Pages (from-to)e51-e52
ISSN1875-1768
DOIs
Publication statusPublished - 2013

    Research areas

  • Allelic drop-out, Degradation, Forensic genetics, Stutter correction, Truncation

ID: 301362879