Estimating drop-out probabilities of STR alleles accounting for stutters, detection threshold truncation and degradation
Research output: Contribution to journal › Journal article › Research › peer-review
Allelic drop-out continues to be a challenge to forensic geneticists when interpreting crime scene evidence and calculating the evidential weight. Methods exist for estimating the probability of allelic drop-out, where the most promising methods use the signal intensities as input for quantifying the drop-out probability. Using data from real crime cases, we demonstrate that taking degradation of the biological material and truncation of the data due to a detection threshold into account is superior to previous approaches. An additional correction for stuttering effects showed limited improvement.
Original language | English |
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Journal | Forensic Science International: Genetics Supplement Series |
Volume | 4 |
Issue number | 1 |
Pages (from-to) | e51-e52 |
ISSN | 1875-1768 |
DOIs | |
Publication status | Published - 2013 |
- Allelic drop-out, Degradation, Forensic genetics, Stutter correction, Truncation
Research areas
ID: 301362879