Enterococcus phage Nonaheksakonda infecting clinical isolates of Enterococcus faecalis represents a new lineage in the family Siphoviridae
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Enterococcus phage Nonaheksakonda was isolated from wastewater, using a vancomycin-resistant strain of the opportunistic pathogen Enterococcus faecalis (VRE) as a host. Nonaheksakonda is a lytic phage infecting E. faecalis V583 and clinical isolates with at least four different multi-locus sequence types (MLSTs). The genome is a 41.9-kb double-stranded DNA molecule (34.6% GC) with 74 coding sequences. Comparative analysis revealed only one close relative, Enterococcus phage heks. All other phages had low protein similarity and shared less than 54% nucleotide sequence identity with phage Nonaheksakonda. The most similar phages were all classified and unclassified efquatroviruses. We propose that the phages Nonaheksakonda and heks represent a novel genus within the family Siphoviridae, order Caudovirales, for which we propose the name "Nonaheksakondavirus".
Original language | English |
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Journal | Archives of Virology |
Volume | 166 |
Pages (from-to) | 593-599 |
Number of pages | 7 |
ISSN | 0304-8608 |
DOIs | |
Publication status | Published - 2021 |
- COMPLETE GENOME SEQUENCE, BACTERIOPHAGE, RESISTANCE, PREDICTION, COMMENSALS, VIRULENCE, GENES
Research areas
ID: 255692425