Effects of the vasopressin agonist terlipressin on plasma cAMP and ENaC excretion in the urine in patients with cirrhosis and water retention

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Effects of the vasopressin agonist terlipressin on plasma cAMP and ENaC excretion in the urine in patients with cirrhosis and water retention. / Krag, Aleksander; Pedersen, Erling B; Møller, Søren; Bendtsen, Flemming; Pedersen, Erling.

In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 71, No. 2, 04.2011, p. 112-6.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Krag, A, Pedersen, EB, Møller, S, Bendtsen, F & Pedersen, E 2011, 'Effects of the vasopressin agonist terlipressin on plasma cAMP and ENaC excretion in the urine in patients with cirrhosis and water retention', Scandinavian Journal of Clinical & Laboratory Investigation, vol. 71, no. 2, pp. 112-6. https://doi.org/10.3109/00365513.2010.537369, https://doi.org/10.3109/00365513.2010.537369

APA

Krag, A., Pedersen, E. B., Møller, S., Bendtsen, F., & Pedersen, E. (2011). Effects of the vasopressin agonist terlipressin on plasma cAMP and ENaC excretion in the urine in patients with cirrhosis and water retention. Scandinavian Journal of Clinical & Laboratory Investigation, 71(2), 112-6. https://doi.org/10.3109/00365513.2010.537369, https://doi.org/10.3109/00365513.2010.537369

Vancouver

Krag A, Pedersen EB, Møller S, Bendtsen F, Pedersen E. Effects of the vasopressin agonist terlipressin on plasma cAMP and ENaC excretion in the urine in patients with cirrhosis and water retention. Scandinavian Journal of Clinical & Laboratory Investigation. 2011 Apr;71(2):112-6. https://doi.org/10.3109/00365513.2010.537369, https://doi.org/10.3109/00365513.2010.537369

Author

Krag, Aleksander ; Pedersen, Erling B ; Møller, Søren ; Bendtsen, Flemming ; Pedersen, Erling. / Effects of the vasopressin agonist terlipressin on plasma cAMP and ENaC excretion in the urine in patients with cirrhosis and water retention. In: Scandinavian Journal of Clinical & Laboratory Investigation. 2011 ; Vol. 71, No. 2. pp. 112-6.

Bibtex

@article{e669fcc281c74ec3828221d7922825fb,
title = "Effects of the vasopressin agonist terlipressin on plasma cAMP and ENaC excretion in the urine in patients with cirrhosis and water retention",
abstract = "Terlipressin is a vasopressin analogue used for its potent V1a effects in cirrhotic patients. Recent data suggest that terlipressin has affinity to renal V2 receptors and modulates Aquaporin 2 (AQP2) expression and free water clearance. Stimulation of renal V2 receptors may also affect sodium transport via the Epithelial Sodium Channel (ENaC). Furthermore, endothelial V2 receptors may indirectly affect proximal sodium handling by increasing plasma cAMP.",
author = "Aleksander Krag and Pedersen, {Erling B} and S{\o}ren M{\o}ller and Flemming Bendtsen and Erling Pedersen",
year = "2011",
month = apr,
doi = "10.3109/00365513.2010.537369",
language = "English",
volume = "71",
pages = "112--6",
journal = "Scandinavian Journal of Clinical & Laboratory Investigation",
issn = "0036-5513",
publisher = "Taylor & Francis",
number = "2",

}

RIS

TY - JOUR

T1 - Effects of the vasopressin agonist terlipressin on plasma cAMP and ENaC excretion in the urine in patients with cirrhosis and water retention

AU - Krag, Aleksander

AU - Pedersen, Erling B

AU - Møller, Søren

AU - Bendtsen, Flemming

AU - Pedersen, Erling

PY - 2011/4

Y1 - 2011/4

N2 - Terlipressin is a vasopressin analogue used for its potent V1a effects in cirrhotic patients. Recent data suggest that terlipressin has affinity to renal V2 receptors and modulates Aquaporin 2 (AQP2) expression and free water clearance. Stimulation of renal V2 receptors may also affect sodium transport via the Epithelial Sodium Channel (ENaC). Furthermore, endothelial V2 receptors may indirectly affect proximal sodium handling by increasing plasma cAMP.

AB - Terlipressin is a vasopressin analogue used for its potent V1a effects in cirrhotic patients. Recent data suggest that terlipressin has affinity to renal V2 receptors and modulates Aquaporin 2 (AQP2) expression and free water clearance. Stimulation of renal V2 receptors may also affect sodium transport via the Epithelial Sodium Channel (ENaC). Furthermore, endothelial V2 receptors may indirectly affect proximal sodium handling by increasing plasma cAMP.

U2 - 10.3109/00365513.2010.537369

DO - 10.3109/00365513.2010.537369

M3 - Journal article

C2 - 21080762

VL - 71

SP - 112

EP - 116

JO - Scandinavian Journal of Clinical & Laboratory Investigation

JF - Scandinavian Journal of Clinical & Laboratory Investigation

SN - 0036-5513

IS - 2

ER -

ID: 34106548